bitertanol
1-(4-biphenylyloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)-2-butanol
Identification
| Name | bitertanol |
| IUPAC | 3,3-dimethyl-1-(4-phenylphenoxy)-1-(1,2,4-triazol-1-yl)butan-2-ol |
| CAS Number | 55179-31-2 |
| EINECS | 259-513-5 |
| FDA UNII | GR7Z3Z59G9 |
| Molecular Formula | C20 H23 N3 O2 |
| Molecular Weight | 337.42271000 |
| MDL Number | MFCD00055508 |
| Nikkaji Number | J11.455C |
| Beilstein | 0620948 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 5 mg/L @ 20 °C (exp) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | oral-dog LD50 > 5 mg/kg |
| Dermal Toxicity | subcutaneous-mouse LDLo 5 gm/kg |
| Inhalation Toxicity | inhalation-rat LC50 > 717 mg/m3/1H |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | herbicides / pesticides |
| Recommendation for bitertanol usage levels up to | not for fragrance use. |
| Recommendation for bitertanol flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
b-[(1,1'-
biphenyl)-4-yloxy]-a-(1,1-dimethylethyl)-1H-1,2,4-triazol-1-ethanol
1-(4-
biphenylyloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)-2-butanol
3,3-
dimethyl-1-(4-phenylphenoxy)-1-(1,2,4-triazol-1-yl)butan-2-ol
1H-1,2,4-
triazole-1-ethanol, b-([1,1'-biphenyl]-4-yloxy)-a-(1,1-dimethylethyl)-
PubMed:
Effects of currently used pesticides and their mixtures on the function of thyroid hormone and aryl hydrocarbon receptor in cell culture.
PubMed:
Direct enantioseparation of nitrogen-heterocyclic pesticides on cellulose-based chiral column by high-performance liquid chromatography.
PubMed:
Testing for cognitive function in animals in a regulatory context.
PubMed:
In vitro-in vivo correlations for endocrine activity of a mixture of currently used pesticides.
PubMed:
Currently used pesticides and their mixtures affect the function of sex hormone receptors and aromatase enzyme activity.
PubMed:
Levels of pesticides and their metabolites in Wistar rat amniotic fluids and maternal urine upon gestational exposure.
PubMed:
Kinetic aspects and identification of by-products during the ozonation of bitertanol in agricultural wastewaters.
PubMed:
Determination of fungicide residues in baby food by liquid chromatography-ion trap tandem mass spectrometry.
PubMed:
A high-throughput approach for the determination of pesticide residues in cucumber samples using solid-phase microextraction on 96-well plate.
PubMed:
HPLC-MS/MS enantioseparation of triazole fungicides using polysaccharide-based stationary phases.
PubMed:
Influence of pesticides on yeasts colonizing leaves.
PubMed:
Development of a gas chromatography-mass spectrometry method for the determination of pesticides in gaseous and particulate phases in the atmosphere.
PubMed:
CYP1A inhibition in fish gill filaments: a novel assay applied on pharmaceuticals and other chemicals.
PubMed:
Development of a rapid determination of pesticides in coated seeds using a high-performance liquid chromatography-UV detection system.
PubMed:
Desorption electrospray ionization mass spectrometry for trace analysis of agrochemicals in food.
PubMed:
Determination of pesticides in water samples from the Wieprz-krzna Canal in the LeczyÅsko-WÅodawskie Lake District of southeastern Poland by thin-layer chromatography with diode array scanning and high-performance column liquid chromatography with diode array detection.
PubMed:
Analysis of currently used pesticides in fine airborne particulate matter (PM 2.5) by pressurized liquid extraction and liquid chromatography-tandem mass spectrometry.
PubMed:
Fungicide seed treatment efficacy against Microdochium nivale and M. majus in vitro and in vivo.
PubMed:
Quantitative Fusarium spp. and Microdochium spp. PCR assays to evaluate seed treatments for the control of Fusarium seedling blight of wheat.
PubMed:
Analyses of pesticide residues in fruit-based baby food by liquid chromatography/electrospray ionization time-of-flight mass spectrometry.
PubMed:
Induction and inhibition of cytochrome P450-dependent monooxygenases of rats by fungicide bitertanol.
PubMed:
Capillary electrophoresis for analyzing pesticides in fruits and vegetables using solid-phase extraction and stir-bar sorptive extraction.
PubMed:
Evaluation of solid-phase extraction and stir-bar sorptive extraction for the determination of fungicide residues at low-microg kg(-1) levels in grapes by liquid chromatography-mass spectrometry.
PubMed:
Determination of fungicide residues in fruits by coupled-column liquid chromatography.
PubMed:
Determination of tridemorph and other fungicide residues in fruit samples by liquid chromatography-electrospray tandem mass spectrometry.
PubMed:
Evaluation of a method based on liquid chromatography/electrospray tandem mass spectrometry for analyzing eight triazolic and pyrimidine fungicides in extracts of processed fruits and vegetables.
PubMed:
[Inhibitory effect of zinc on beta-hexosaminidase release from RBL-2H3 cells by synthetic chemicals].
PubMed:
Determination of seventeen polar/thermolabile pesticides in apples and apricots by liquid chromatography/mass spectrometry.
PubMed:
Comparison of microextraction procedures to determine pesticides in oranges by liquid chromatography-mass spectrometry.
PubMed:
Pesticide residues in agricultural products monitored in Hyogo Prefecture, Japan, FYs 1995-1999.
PubMed:
[Effects of organonitrogen, carbamate pesticides and others on beta-hexosaminidase release from rat basophilic leukemia cells (RBL-2H3)].
PubMed:
Assessment of the stability of pesticides during cryogenic sample processing. 1. Apples.
PubMed:
Possible bitertanol and fuberidazole poisoning in young pheasants.
PubMed:
High-performance chiral separation of fourteen triazole fungicides by sulfated beta-cyclodextrin-mediated capillary electrophoresis.
PubMed:
Multiresidue determination of 19 fungicides in processed fruits and vegetables by capillary gas chromatography after gel permeation chromatography.
PubMed:
Determination of bitertanol residues in strawberries by liquid chromatography with fluorescence detection and confirmation by gas chromatography/mass spectrometry.
PubMed:
A novel ATP-binding cassette transporter involved in multidrug resistance in the phytopathogenic fungus Penicillium digitatum.
PubMed:
Simple and rapid method for simultaneous gas chromatographic determination of bitertanol, metalaxyl, oxadixyl, propiconazole, and triadimefon residues in cucumbers.
PubMed:
Bitertanol, a triazole fungicide, increases operant responding but not motor activity.