seneciphylline-N-oxide
senecionan-11,16-dione, 13,19-didehydro-12-hydroxy-, 4-oxide
Identification
| Name | seneciphylline-N-oxide |
| CAS Number | 38710-26-8 |
| FDA UNII | Search |
| Molecular Formula | C18 H23 N O6 |
| Molecular Weight | 349.38351000 |
| Nikkaji Number | J1.038.288B |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 1e+006 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for seneciphylline-N-oxide usage levels up to | not for fragrance use. |
| Recommendation for seneciphylline-N-oxide flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
senecionan-11,16-dione, 13,19-didehydro-12-hydroxy-, 4-oxide
seneciphylline N-oxide
PubMed:
Pyrrolizidine alkaloid variation in Senecio vulgaris populations from native and invasive ranges.
PubMed:
UPLC TOF MS for sensitive quantification of naturally occurring pyrrolizidine alkaloids in Petasites hybridus extract (Ze 339).
PubMed:
Identification of five hepatotoxic pyrrolizidine alkaloids in a commonly used traditional Chinese medicinal herb, Herba Senecionis scandentis (Qianliguang).
PubMed:
Loss of gustatory responses to pyrrolizidine alkaloids after their extensive ingestion in the polyphagous caterpillar Estigmene acrea.
PubMed:
Experience influences gustatory responsiveness to pyrrolizidine alkaloids in the polyphagous caterpillar, Estigmene acrea.
PubMed:
A highly sensitive taste receptor cell for pyrrolizidine alkaloids in the lateral galeal sensillum of a polyphagous caterpillar, Estigmene acraea.
PubMed:
Generation and characterization of monoclonal antibodies against the pyrrolizidine alkaloid retrorsine.