isoamyl acetate

isopentyl acetate

CAS: 123-92-2 C7 H14 O2 MW: 130.18698000 fruity fruity

Identification

Nameisoamyl acetate
IUPAC3-methylbutyl acetate
CAS Number123-92-2
EINECS204-662-3
FDA UNIIZ135787824
Molecular FormulaC7 H14 O2
Molecular Weight130.18698000
MDL NumberMFCD00008946
Nikkaji NumberJ2.012E
Beilstein1744750
CoE Number214
XlogP32.00 (est)

Regulatory

JECFA Food Flavoring43 isoamyl acetate
JECFA Food AdditiveIsoamyl Acetate
DG SANTE Food Flavourings09.024 isopentyl acetate
FEMA Number2055
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)123-92-2 ; ISOAMYL ACETATE
FDA RegulationFDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION

Physical Properties

Appearance colorless clear liquid (est)
Assay 99.00 to 100.00
Food Chemicals Codex Listed Yes
Specific Gravity 0.86000 to 0.87800 @ 25.00 °C.
Pounds per Gallon - (est). 7.156 to 7.306
Refractive Index 1.40000 to 1.40400 @ 20.00 °C.
Melting Point -78.00 °C. @ 760.00 mm Hg
Boiling Point 142.00 to 143.00 °C. @ 756.00 mm Hg, 30.00 °C. @ 2.00 mm Hg
Acid Value 1.00 max. KOH/g
Vapor Pressure 5.600000 mmHg @ 25.00 °C.
Vapor Density 4.4 ( Air = 1 )
Flash Point 77.00 °F. TCC ( 25.00 °C. )
logP (o/w) 2.260
Shelf Life 24.00 month(s) or longer if stored properly.
Storage store in cool, dry place in tightly sealed containers, protected from heat and light.
Soluble in alcohol
Insoluble in water
Similar Items note

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesfragrance

Organoleptic Properties

Odor Strength high ,
Substantivity < 4 hour(s) at 100.00 %
Odor Description
at 10.00 % in dipropylene glycol.
Sweet, banana, fruity with a ripe estry nuance
sweet banana fruity ripe estery
Odor sample from Fritzsche Dodge & Olcott, Inc.
Natural Odor Description at 10.00 % in dipropylene glycol.
Natural odor sample from Berje Inc.
Taste Description
at 30.00 ppm in propylene glycol.
sweet, fruity, estery, banana- and pear-like

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Human Experience8 % solution: no irritation or sensitization
Oral/Parenteral Toxicityoral-rat LD50 16600 mg/kg
Dermal Toxicityskin-rabbit LD50 > 5000 mg/kg
Inhalation Toxicityinhalation-cat LCLo 35000 mg/m3

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements', 'BEHAVIORAL: GENERAL ANESTHETIC\nPERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE']

Safety in Use

Categorycarrier solvents, flavoring agents
RIFM Fragrance Material Safety AssessmentSearch
Recommendation for isoamyl acetate usage levels up to25.0000 % in the fragrance concentrate.
baked goods-
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum-
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy-
fruit ices-
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

Advanced Biotech. Inc.

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Alfrebro LLC/ Archer Daniels Midland Company

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Axxence Aromatic GmbH

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Berje Inc.

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ECSA Chemicals

Human Chemistry

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Elan Inc.

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Excellentia International

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Fleurchem, Inc.

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FRUTAROM USA INC,

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M&U International LLC

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Moellhausen S.P.A.

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Penta International Corporation

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PerfumersWorld Ltd.

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Prodasynth

PRODUCTEUR PAR ESSENCE

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Robertet, Inc.

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Sigma-Aldrich

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SRS Aromatics Ltd

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Symrise AG

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The John D. Walsh Company, Inc

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Zanos Ltd.

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Potential Uses

FR almond FR apple FR apple red apple FR apricot FR banana FR blackberry FR blueberry FL brandy FR bubble gum FR butterscotch FR carnation FR cherry FL chocolate cocoa FR coconut FR coffee FR crabapple blossom FR cranberry FR currant FR date FR floral FR fruit juicy fruit FR gooseberry FR grape FL grenadine FR hibiscus FR honey FR hop FR huckleberry FR hyacinth FR lemon FR lily of the valley FR lime FR melon FR mint FR mulberry FR orange FR oriental FR passion fruit FR peach FR pear FR pina colada FR pineapple FL pistachio FR plum FR quince FR raspberry FR rose FR strawberry FR tangerine FL/FR valerian FR vanilla FR violet

Natural Occurrence

apple fruit apple juice PMC banana fruit beer PMC butter PMC chamomile oil @ 0.93% Data PMC cocoa bean elder black elder flower oil fig fruit guava fruit papaya fruit plum fruit plumcot fruit PMC strawberry wild strawberry fruit tea leaf wine PMC

Synonyms

acetic acid 3-methyl butyl ester acetic acid 3-methylbutyl ester acetic acid isoamyl ester acetic acid isopentyl ester acetic acid, 3-methylbutyl ester acetic acid, isopentyl ester iso- amyl acetate nat.iso amyl acetate iso amyl acetate (natural) iso amyl acetate 35% double peak iso amyl acetate 65% double peak iso amyl acetate 98% (single isomer) iso amyl acetate FCC iso amyl acetate FCC (natural) iso amyl acetate natural iso amyl acetate naturel iso amyl acetate pure iso amyl acetate single peak iso amyl acetate, natural iso amyl ethanoate iso- amyl-acetate butanol, 3-methyl-, acetate 1- butanol, 3-methyl-, acetate 3- methyl butyl acetate beta- methyl butyl acetate 2- methyl butyl ethanoate 3- methyl butyl ethanoate 3- methyl-1-butanol acetate 3- methyl-1-butanol, acetate 3- methyl-1-butyl acetate 3- methyl-but-1-yl acetate 3- methylbutyl acetate 3- methylbutyl ester of acetic acid 3- methylbutyl ethanoate (3- methylbutyl) ethanoate iso pentyl acetate iso pentyl alcohol acetate iso pentyl alcohol, acetate iso pentyl ethanoate Info: Volatile Flavor Components in Bogyojosaeng and Suhong Cultivars of Strawberry (Fragaria ananassa Duch.) PubMed: Targeting key aromatic substances on the typical aroma of sherry vinegar. J-Stage: Characterization and Isolation of Mutants Producing Increased Amounts of Isoamyl Acetate Derived from Hygromycin B-Resistant Sake Yeast PubMed: Microbial ecology studies of spontaneous fermentation: starter culture selection for prickly pear wine production. PubMed: Beer volatile analysis: optimization of HS/SPME coupled to GC/MS/FID. PubMed: Classification of wines from five Spanish origin denominations by aromatic compound analysis. PubMed: Physiological characterization of brewer's yeast in high-gravity beer fermentations with glucose or maltose syrups as adjuncts. PubMed: Isolation of sake yeast mutants producing a high level of ethyl caproate and/or isoamyl acetate. PubMed: Odor-active headspace components in fermented red rice in the presence of a monascus species. PubMed: Controlled continuous flow delivery system for investigating taste-aroma interactions. PubMed: Effect of wild strains of Lactococcus lactis on the volatile profile and the sensory characteristics of ewes' raw milk cheese. PubMed: Headspace solid-phase microextraction method for the study of the volatility of selected flavor compounds. PubMed: Genetic and physiological analysis of branched-chain alcohols and isoamyl acetate production in Saccharomyces cerevisiae. PubMed: Flavor release in the presence of melanoidins prepared from L-(+)-ascorbic acid and amino acids. PubMed: Interactions between wine polyphenols and aroma substances. An insight at the molecular level. PubMed: A study on volatile organic compounds (VOCs) produced by tropical ascomycetous yeasts. PubMed: Antimicrobial properties and mechanism of volatile isoamyl acetate, a main flavour component of Japanese sake (Ginjo-shu). PubMed: Effects of fermentation temperature and aeration on production of natural isoamyl acetate by Williopsis saturnus var. saturnus. PubMed: Characterization and isolation of mutants producing increased amounts of isoamyl acetate derived from hygromycin B-resistant sake yeast. PubMed: Discrimination of varietal wines according to their volatiles. PubMed: Lipase of Aspergillus niger NCIM 1207: A Potential Biocatalyst for Synthesis of Isoamyl Acetate. PubMed: The Context of Chemical Communication Driving a Mutualism. PubMed: Metabolic engineering of the anaerobic central metabolic pathway in Escherichia coli for the simultaneous anaerobic production of isoamyl acetate and succinic acid. PubMed: Kinetics of lipase catalyzed isoamyl acetate synthesis at high hydrostatic pressure in hexane. PubMed: Identification of odor-active 3-mercapto-3-methylbutyl acetate in volatile fraction of roasted coffee brew isolated by steam distillation under reduced pressure. PubMed: Release and uptake of volatile organic compounds by human hepatocellular carcinoma cells (HepG2) in vitro. PubMed: Crystal structure of isoamyl acetate-hydrolyzing esterase from Saccharomyces cerevisiae reveals a novel active site architecture and the basis of substrate specificity. PubMed: Lipase-catalyzed synthesis of isoamyl acetate in an ionic liquid/n-heptane two-phase system at the microreactor scale. PubMed: Glycerol triacetate as solvent and acyl donor in the production of isoamyl acetate with Candida antarctica lipase B. PubMed: Analysis of volatile organic compounds liberated and metabolised by human umbilical vein endothelial cells (HUVEC) in vitro. PubMed: Quantitative analysis of volatile organic compounds released and consumed by rat L6 skeletal muscle cells in vitro. PubMed: Microbiota and metabolites of aged bottled gueuze beers converge to the same composition. PubMed: Applicability of CoA/acetyl-CoA manipulation system to enhance isoamyl acetate production in Escherichia coli. PubMed: Characterization of the key aroma compounds in two bavarian wheat beers by means of the sensomics approach. PubMed: Using promoter replacement and selection for loss of heterozygosity to generate an industrially applicable sake yeast strain that homozygously overproduces isoamyl acetate. PubMed: Engineered biosynthesis of medium-chain esters in Escherichia coli. PubMed: Nutritional status modulates behavioural and olfactory bulb Fos responses to isoamyl acetate or food odour in rats: roles of orexins and leptin. PubMed: Aerobic production of isoamyl acetate by overexpression of the yeast alcohol acetyl-transferases AFT1 and AFT2 in Escherichia coli and using low-cost fermentation ingredients. PubMed: Balance of activities of alcohol acetyltransferase and esterase in Saccharomyces cerevisiae is important for production of isoamyl acetate. PubMed: Seasonal increase in olfactory receptor neurons of the Japanese toad, Bufo japonicus, is paralleled by an increase in olfactory sensitivity to isoamyl acetate. PubMed: Genetic and physiological analysis of branched-chain alcohols and isoamyl acetate production in Saccharomyces cerevisiae. PubMed: Acetate ester production by Chinese yellow rice wine yeast overexpressing the alcohol acetyltransferase-encoding gene ATF2. PubMed: Improved production of isoamyl acetate by a sake yeast mutant resistant to an isoprenoid analog and its dependence on alcohol acetyltransferase activity, but not on isoamyl alcohol production. PubMed: Heterologous expression of the Saccharomyces cerevisiae alcohol acetyltransferase genes in Clostridium acetobutylicum and Escherichia coli for the production of isoamyl acetate. PubMed: Enzymatic synthesis of isoamyl acetate using immobilized lipase from Rhizomucor miehei. PubMed: Odorant metabolism catalyzed by olfactory mucosal enzymes influences peripheral olfactory responses in rats. PubMed: Functional imaging of olfaction by CBV fMRI in monkeys: insight into the role of olfactory bulb in habituation. PubMed: Proteins involved in wine aroma compounds metabolism by a Saccharomyces cerevisiae flor-velum yeast strain grown in two conditions. PubMed: Analysis of beers from an 1840s' shipwreck. PubMed: A kinetic study of isoamyl acetate synthesis by immobilized lipase-catalyzed acetylation in n-hexane. PubMed: Redistribution of metabolic fluxes in the central aerobic metabolic pathway of E. coli mutant strains with deletion of the ackA-pta and poxB pathways for the synthesis of isoamyl acetate. PubMed: Release of isoamyl acetate from starch pastes of various structures: thermodynamic and kinetic parameters. PubMed: Enhanced isoamyl acetate production upon manipulation of the acetyl-CoA node in Escherichia coli. PubMed: Production of isoamyl acetate in ackA-pta and/or ldh mutants of Escherichia coli with overexpression of yeast ATF2. PubMed: Improvement of isoamyl acetate productivity in sake yeast by isolating mutants resistant to econazole. PubMed: Applicability of Lactobacillus plantarum IMDO 788 as a starter culture to control vegetable fermentations. PubMed: Volatile constituents of commercial imported and domestic black-ripe table olives (Olea europaea). PubMed: Enhanced production of isoamyl alcohol and isoamyl acetate by ubiquitination-deficient Saccharomyces cerevisiae mutants. PubMed: Electroencephalographic registration of low concentrations of isoamyl acetate. PubMed: [Olfactory event-related potentials to isoamyl acetate in congenital anosmia]. PubMed: A kinetic study of immobilized lipase catalysing the synthesis of isoamyl acetate by transesterification in n-hexane. PubMed: Involvement of a specific chemosensory protein from Bactrocera dorsalis in perceiving host plant volatiles. PubMed: Avoidance and contextual learning induced by a kairomone, a pheromone and a common odorant in female CD1 mice. PubMed: Ion mobility spectrometry for detection of skin volatiles. PubMed: Isolation of sake yeast mutants producing a high level of ethyl caproate and/or isoamyl acetate. PubMed: Purification and characterization of isoamyl acetate-hydrolyzing esterase encoded by the IAH1 gene of Saccharomyces cerevisiae from a recombinant Escherichia coli. PubMed: Characterization of aroma compounds of Chinese famous liquors by gas chromatography-mass spectrometry and flash GC electronic-nose. PubMed: Comparative physiology and fermentation performance of Saaz and Frohberg lager yeast strains and the parental species Saccharomyces eubayanus. PubMed: Comprehensive study of the evolution of gas-liquid partitioning of aroma compounds during wine alcoholic fermentation. PubMed: Adaptive evolution of the lager brewing yeast Saccharomyces pastorianus for improved growth under hyperosmotic conditions and its influence on fermentation performance. PubMed: Classification of wines from five Spanish origin denominations by aromatic compound analysis. PubMed: Severe extrapyramidal syndrome after exposition to isoamyl acetate vapour. PubMed: Optimization of isoamyl acetate production by using immobilized lipase from Mucor miehei by response surface methodology. PubMed: Identification of isoamyl acetate as an active component in the sting pheromone of the honey bee. PubMed: In vitro determination of volatile compound development during starter culture-controlled fermentation of Cucurbitaceae cotyledons. PubMed: Aroma-active ester profile of ale beer produced under different fermentation and nutritional conditions. PubMed: Exposure models for the prior distribution in bayesian decision analysis for occupational hygiene decision making. PubMed: Identification and field evaluation of pear fruit volatiles attractive to the oriental fruit moth, Cydia molesta. PubMed: Isoamylacetate production by entrapped and covalently bound Candida rugosa and porcine pancreatic lipases. PubMed: Physical Properties, Volatiles Compositions and Sensory Descriptions of the Aromatized Hazelnut Oil-Wax Organogels. PubMed: Increase of fruity aroma during mixed T. delbrueckii/S. cerevisiae wine fermentation is linked to specific esters enhancement. PubMed: Characterization of an Endophytic Gloeosporium sp. and Its Novel Bioactivity with "Synergistans". PubMed: Volatile Compounds from Grape Skin, Juice and Wine from Five Interspecific Hybrid Grape Cultivars Grown in Québec (Canada) for Wine Production. PubMed: Bioflavour production from tomato and pepper pomaces by Kluyveromyces marxianus and Debaryomyces hansenii. PubMed: Assessment of volatile and non-volatile compounds in durian wines fermented with four commercial non-Saccharomyces yeasts. PubMed: Olfactory biosensor for insect semiochemicals analysis by impedance sensing of odorant-binding proteins on interdigitated electrodes. PubMed: Early leaf removal impact on volatile composition of Tempranillo wines. PubMed: A physiological increase of insulin in the olfactory bulb decreases detection of a learned aversive odor and abolishes food odor-induced sniffing behavior in rats. PubMed: Combined effects of nutrients and temperature on the production of fermentative aromas by Saccharomyces cerevisiae during wine fermentation. PubMed: Contribution to the aroma of white wines by controlled Torulaspora delbrueckii cultures in association with Saccharomyces cerevisiae. PubMed: Microbiology of sugar-rich environments: diversity, ecology and system constraints. PubMed: Production of aroma compounds from whey using Wickerhamomyces pijperi. PubMed: Influence of carbon and nitrogen source on production of volatile fragrance and flavour metabolites by the yeast Kluyveromyces marxianus. PubMed: Method development by GC-ECD and HS-SPME-GC-MS for beer volatile analysis. PubMed: Dynamics and quantitative analysis of the synthesis of fermentative aromas by an evolved wine strain of Saccharomyces cerevisiae. PubMed: Identification of host fruit volatiles from three mayhaw species (Crataegus series Aestivales) attractive to mayhaw-origin Rhagoletis pomonella flies in the southern United States. PubMed: The fungal aroma gene ATF1 promotes dispersal of yeast cells through insect vectors. PubMed: Isolation, selection and evaluation of yeasts for use in fermentation of coffee beans by the wet process. PubMed: Long-term storage of aerobic granules in liquid media: viable but non-culturable status. PubMed: Separation of positional isomers by the use of coupled shape-selective stationary phase columns. PubMed: Prevalence and impact of single-strain starter cultures of lactic acid bacteria on metabolite formation in sourdough. PubMed: Interactions between Torulaspora delbrueckii and Saccharomyces cerevisiae in wine fermentation: influence of inoculation and nitrogen content. PubMed: Microbial species diversity, community dynamics, and metabolite kinetics of water kefir fermentation. PubMed: Pomegranate juice adulteration by addition of grape or peach juices. PubMed: Characterization of odor-active compounds in guava wine. PubMed: Social modulation of stress reactivity and learning in young worker honey bees. PubMed: Short-chain flavor ester synthesis in organic media by an E. coli whole-cell biocatalyst expressing a newly characterized heterologous lipase. PubMed: Olfactory detection thresholds and pleasantness of a food-related and a non-food odour in hunger and satiety. PubMed: A bitter sweet asynchrony. The relation between eating attitudes, dietary restraint on smell and taste function. PubMed: Influence of phenolic compounds on the sensorial perception and volatility of red wine esters in model solution: an insight at the molecular level. PubMed: Beer volatile analysis: optimization of HS/SPME coupled to GC/MS/FID. PubMed: Purification and properties of Amycolatopsis mediterranei DSM 43304 lipase and its potential in flavour ester synthesis. PubMed: High-cell-density fermentation of Saccharomyces cerevisiae for the optimisation of mead production. PubMed: Foraging behavior of the dead leaf butterfly, Kallima inachus. PubMed: Isolation and characterization of CaMF3, an anther-specific gene in Capsicum annuum L. PubMed: Rapid odor perception in rat olfactory bulb by microelectrode array. PubMed: Feasibility of brewing makgeolli using Pichia anomala Y197-13, a non-Saccharomyces cerevisiae. PubMed: Primary culture of embryonic rat olfactory receptor neurons. PubMed: Identification and field evaluation of fermentation volatiles from wine and vinegar that mediate attraction of spotted wing Drosophila, Drosophila suzukii. PubMed: Construction of self-cloning bottom-fermenting yeast with low vicinal diketone production by the homo-integration of ILV5. PubMed: Differential transfer of dietary flavour compounds into human breast milk. PubMed: Effect of pH on the thermal stability of potent roasty odorants, 3-mercapto-3-methylbutyl esters, in coffee drink. PubMed: Odorant specificity of three oscillations and the DC signal in the turtle olfactory bulb. PubMed: Short-chain and medium-chain aliphatic-ester synthesis in Saccharomyces cerevisiae. PubMed: [Olfactory functional magnetic resonance imaging with modified OEP-98C olfactometer and event-related design]. PubMed: A comparison of laboratory and pilot-scale fermentations in winemaking conditions. PubMed: Saccharomyces cerevisiae oxidative response evaluation by cyclic voltammetry and gas chromatography-mass spectrometry. PubMed: Production of flavor esters catalyzed by CALB-displaying Pichia pastoris whole-cells in a batch reactor. PubMed: Imaging evolutionarily conserved neural networks: preferential activation of the olfactory system by food-related odor. PubMed: Comparative metabolic profiling to investigate the contribution of O. oeni MLF starter cultures to red wine composition. PubMed: Sweet taste intensity is enhanced by temporal fluctuation of aroma and taste, and depends on phase shift. PubMed: Interactions of odorants with olfactory receptors and receptor neurons match the perceptual dynamics observed for woody and fruity odorant mixtures. PubMed: Detection of neural activity in the brains of Japanese honeybee workers during the formation of a "hot defensive bee ball". PubMed: Chemotactic effect of odorants and tastants on the ciliate Tetrahymena pyriformis. PubMed: Effect of oxygen on volatile and sensory characteristics of Cabernet Sauvignon during secondary shelf life. PubMed: Increased expression of peroxiredoxin 1 and identification of a novel lipid-metabolizing enzyme in the early phase of liver ischemia reperfusion injury. PubMed: Olfactory performance of patients with anorexia nervosa and healthy subjects in hunger and satiety. PubMed: Influence of the structure of cornstarch dispersions on kinetics of aroma release. PubMed: Retention of aroma compounds in starch matrices: competitions between aroma compounds toward amylose and amylopectin. PubMed: Odorant-induced hyperpolarization and suppression of cAMP-activated current in newt olfactory receptor neurons. PubMed: Microbial ecology studies of spontaneous fermentation: starter culture selection for prickly pear wine production. PubMed: Impact of cover crops in vineyard on the aroma compounds of Vitis vinifera L. cv Cabernet Sauvignon wine. PubMed: Generation of volatile compounds in litchi wine during winemaking and short-term bottle storage. PubMed: Synthesis of 2H-1,2-benzothiazine 1,1-dioxides via heteroannulation reactions of 2-iodobenzenesulfonamide with ketone enolates under S(RN)1 conditions. PubMed: The effect of increased yeast alcohol acetyltransferase and esterase activity on the flavour profiles of wine and distillates. PubMed: Influence of lipid fraction, emulsifier fraction, and mean particle diameter of oil-in-water emulsions on the release of 20 aroma compounds. PubMed: Interactions between artificial saliva and 20 aroma compounds in water and oil model systems. PubMed: BioBuilding using banana-scented bacteria to teach synthetic biology. PubMed: Phosphoinositide 3-kinase-dependent antagonism in mammalian olfactory receptor neurons. PubMed: Volatile compounds of young wines from cabernet sauvignon, cabernet gernischet and chardonnay varieties grown in the loess plateau region of china. PubMed: Flavor release in the presence of melanoidins prepared from L-(+)-ascorbic acid and amino acids. PubMed: Odor exposure causes central adaptation and morphological changes in selected olfactory glomeruli in Drosophila. PubMed: Olfactory experience decreases responsiveness of the olfactory bulb in the adult rat. PubMed: Increased olfactory sensitivity in first episode psychosis and the effect of neuroleptic treatment on olfactory sensitivity in schizophrenia. PubMed: Selective and reversible blockage of a fatty acid odour response in the olfactory bulb of the frog (Rana temporaria). PubMed: Responses to odorants by the domestic chick. PubMed: Trigeminal perception is necessary to localize odors. PubMed: Metabolomics reveals alterations in both primary and secondary metabolites by wine bacteria. PubMed: Simultaneous sampling of volatile and non-volatile analytes in beer for fast fingerprinting by extractive electrospray ionization mass spectrometry. 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