Identification

Namementhyl acetate racemic
IUPAC(5-methyl-2-propan-2-ylcyclohexyl) acetate
CAS Number16409-45-3
EINECS240-459-6
FDA UNIISearch
Molecular FormulaC12 H22 O2
Molecular Weight198.30574000
MDL NumberMFCD00062975
Nikkaji NumberJ156.147B
CoE Number206

Regulatory

JECFA Food Flavoring431 menthyl acetate
FEMA Number2668
FDANo longer provide for the use of these seven synthetic flavoring substances

Physical Properties

Appearance colorless clear liquid (est)
Assay 97.00 to 100.00
Food Chemicals Codex Listed Yes
Specific Gravity 0.92200 to 0.93100 @ 25.00 °C.
Pounds per Gallon - (est). 7.672 to 7.747
Refractive Index 1.44800 to 1.45000 @ 20.00 °C.
Boiling Point 227.00 to 229.00 °C. @ 760.00 mm Hg
Acid Value 1.00 max. KOH/g
Vapor Pressure 0.071000 mmHg @ 25.00 °C. (est)
Flash Point 198.00 °F. TCC ( 92.22 °C. )
logP (o/w) 4.000
Soluble in alcohol
Insoluble in water

Organoleptic Properties

Odor Strength medium
Substantivity 12 hour(s) at 100.00 %
Odor Description at 100.00 %.
Odor sample from CA Aromatics Company Inc.

Safety Information

Preferred SDSView
Human Experience8 % solution: no irritation or sensitization.
Oral/Parenteral Toxicitygavage-rat LD50 [sex: M,F] > 7000 mg/kg
Dermal Toxicityskin-rabbit LD50 > 5000 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavor and fragrance agents
RIFM Fragrance Material Safety AssessmentSearch
Recommendation for menthyl acetate racemic usage levels up to8.0000 % in the fragrance concentrate.
Maximised Survey-derived Daily Intakes (MSDI-EU)270.00 (μg/capita/day)
baked goods-
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum-
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy-
fruit ices-
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

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Potential Uses

FL/FR caraway seed FR citrus FR cologne FR floral FR fruit FR herbal FR lavender FR mint FR oriental FR peppermint FR rose FR spice

Natural Occurrence

buchu oil cornmint leaf cornmint oil eucalyptus oil ginger rhizome oil lemon balm oil mango fruit orange fruit juice peppermint oil spearmint leaf spearmint oil

Synonyms

acetic acid p-menth-3-yl ester acetic acid para-menth-3-yl ester acetic acid, p-menth-3-yl ester cyclohexanol, 5-methyl-2-(1-methylethyl)-, acetate p- menthan-3-yl acetate para- menthan-3-yl acetate (±)- menthol acetate menthol, acetate menthyl acetate (±)- menthyl acetate DL- menthyl acetate menthyl acetate natural menthylacetate 5- methyl-2-(1-methyl ethyl) cyclohexanol ethanoate 5- methyl-2-(1-methylethyl)cyclohexanol acetate 5- methyl-2-(1-methylethyl)cyclohexanolethanoate DL-5- methyl-2-(1-methylethyl)cyclohexyl acetate 5- methyl-2-(propan-2-yl)cyclohexyl acetate (5- methyl-2-propan-2-ylcyclohexyl) acetate 2-iso propyl-5-methyl cyclohexyl acetate 2-iso propyl-5-methylcyclohexyl acetate PubMed: Peppermint (Mentha piperita) and albendazole against anisakiasis in an animal model. PubMed: Seasonal variability of the main components in essential oil of Mentha × piperita L. PubMed: Biocontrol potential of essential oil monoterpenes against housefly, Musca domestica (Diptera: Muscidae). PubMed: Biochemical studies on a versatile esterase that is most catalytically active with polyaromatic esters. PubMed: Structure-activity relationships of monoterpenes and acetyl derivatives against Aedes aegypti (Diptera: Culicidae) larvae. PubMed: Chemical Composition, Antifungal and Antibiofilm Activities of the Essential Oil of Mentha piperita L. PubMed: Volatile oil constituents of different parts of Artemisia chamaemelifolia and the composition and antibacterial activity of the aerial parts of A. turcomanica from Iran. PubMed: Antioxidant and antibacterial effects of Lavandula and Mentha essential oils in minced beef inoculated with E. coli O157:H7 and S. aureus during storage at abuse refrigeration temperature. PubMed: Composition of seed essential oils of Rhododendron tomentosum. PubMed: Development of quality assessment method for optically active food flavor chemicals. PubMed: Peppermint oil decreases the production of virulence-associated exoproteins by Staphylococcus aureus. PubMed: An efficient bioprocess for enzymatic production of L-menthol with high ratio of substrate to catalyst using whole cells of recombinant E. coli. PubMed: Chemical composition, olfactory evaluation and antioxidant effects of essential oil from Mentha x piperita. PubMed: Toxicity to vapor exposure and topical application of essential oils and monoterpenes on Musca domestica (Diptera: Muscidae). PubMed: Fumigant insecticidal activity and repellent effect of five essential oils and seven monoterpenes on first-instar nymphs of Rhodnius prolixus. PubMed: Biotransformation of menthol and geraniol by hairy root cultures of Anethum graveolens: effect on growth and volatile components. PubMed: Chemical composition of essential oils of Thymus and Mentha species and their antifungal activities. PubMed: Comparative analysis of some active principles of herb plants by GC/MS. PubMed: Enhancement in skin permeation of 5-aminolevulinic acid using l-menthol and its derivatives. PubMed: Insecticidal activity of menthol derivatives against mosquitoes. PubMed: Lithium amide assisted asymmetric Mannich-type reactions of menthyl acetate with PMP-aldimines. PubMed: Lytic activity of l-menthol derivatives against the snow blight disease fungus, Micronectriella nivalis. PubMed: Esterases from Bacillus subtilis and B. stearothermophilus share high sequence homology but differ substantially in their properties. PubMed: Evaluation of peppermint oil and ascorbyl palmitate as inhibitors of cytochrome P4503A4 activity in vitro and in vivo. PubMed: Effect of Mentha x piperita essential oil and monoterpenes on cucumber root membrane potential. PubMed: Ambulation-promoting effect of peppermint oil and identification of its active constituents. PubMed: Monoterpene composition of essential oil from peppermint (Mentha x piperita L.) with regard to leaf position using solid-phase microextraction and gas chromatography/mass spectrometry analysis. PubMed: Constituents of Essential Oils from Mentha X rotundifolia Growing Wild in Greece. PubMed: Chemical and Morphometrical Comparison Between two Peppermint Notomorphs. PubMed: Metabolism of Monoterpenes : Early Steps in the Metabolism of d-Neomenthyl-beta-d-Glucoside in Peppermint (Mentha piperita) Rhizomes. PubMed: Metabolism of Monoterpenes: Conversion of l-Menthone to l-Menthol and d-Neomenthol by Stereospecific Dehydrogenases from Peppermint (Mentha piperita) Leaves. PubMed: Demonstration of the Intercellular Compartmentation of l-Menthone Metabolism in Peppermint (Mentha piperita) Leaves. PubMed: Metabolism of Monoterpenes : EVIDENCE FOR COMPARTMENTATION OF l-MENTHONE METABOLISM IN PEPPERMINT (MENTHA PIPERITA) LEAVES. PubMed: Metabolism of Monoterpenes: Acetylation of (-)-Menthol by a Soluble Enzyme Preparation from Peppermint (Mentha piperita) Leaves. PubMed: Genetic basis for high limonene-cineole content of exceptional Mentha citrata hybrids. PubMed: The liquid-liquid counter current separation of a menthol-menthyl acetate mixture. PubMed: A note on the preparation of 1-menthyl acetate.