Identification

Nameevodia rutaecarpa fruit oil
IUPACevodia rutaecarpa fruit oil
CAS Number1137739-11-7
FDA UNIISearch

Regulatory

Physical Properties

Food Chemicals Codex Listed No
Soluble in alcohol
Insoluble in water

Organoleptic Properties

Odor Description
at 10.00 % in dipropylene glycol.
sharp greenness on top is reminiscent of hot chilies or pimento

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryfragrance agents
RIFM Fragrance Material Safety AssessmentSearch

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Potential Uses

None Found

Natural Occurrence

evodia rutaecarpa fruit

Synonyms

evodia EO evodia oil PubMed: Analysis of E. rutaecarpa Alkaloids Constituents In Vitro and In Vivo by UPLC-Q-TOF-MS Combined with Diagnostic Fragment. PubMed: Identification and Structural Characterization of Acylgluconic Acids, Flavonol Glycosides, Limonoids and Alkaloids from the Fruits of Evodia Rutaecarpa by High Performance Liquid Chromatography Coupled to Electrospray Ionization and Quadrupole Time-of-Flight Mass Spectrometry. PubMed: Rutaecarpine ameliorates hyperlipidemia and hyperglycemia in fat-fed, streptozotocin-treated rats via regulating the IRS-1/PI3K/Akt and AMPK/ACC2 signaling pathways. PubMed: Therapeutic and cosmetic applications of Evodiamine and its derivatives--A patent review. PubMed: Effect and mechanism of evodiamine against ethanol-induced gastric ulcer in mice by suppressing Rho/NF-кB pathway. PubMed: Evodiamine suppresses capsaicin-induced thermal hyperalgesia through activation and subsequent desensitization of the transient receptor potential V1 channels. PubMed: Evodiamine inhibits the proliferation of human osteosarcoma cells by blocking PI3K/Akt signaling. PubMed: Mechanism-based inhibition of CYPs and RMs-induced hepatoxicity by rutaecarpine. PubMed: A new caffeoylgluconic acid derivative from the nearly ripe fruits of Evodia rutaecarpa. PubMed: Antidepressant-like effect of evodiamine on chronic unpredictable mild stress rats. PubMed: Identification of evodiamine as the bioactive compound in evodia (Evodia rutaecarpa Benth.) fruit extract that activates human peroxisome proliferator-activated receptor gamma (PPARγ). PubMed: Long-term effects of evodiamine on expressions of lipogenesis and lipolysis genes in mouse adipose and liver tissues. PubMed: Gram-scale purification of dehydroevodiamine from Evodia rutaecarpa fruits, and a procedure for selective removal of quaternary indoloquinazoline alkaloids from Evodia extracts. PubMed: Evodiamine inhibits insulin-stimulated mTOR-S6K activation and IRS1 serine phosphorylation in adipocytes and improves glucose tolerance in obese/diabetic mice. PubMed: Subchronic oral toxicity of evodia fruit powder in rats. PubMed: A new indoloquinazoline alkaloidal glucoside from the nearly ripe fruits of Evodia rutaecarpa. PubMed: Quinolone alkaloids with antibacterial and cytotoxic activities from the fruits of Evodia rutaecarpa. PubMed: [Study on the infrared fingerprint of Evodia rutaecarpa based on the methods of sequential analysis of dual-indexes]. PubMed: [Flavonoid glycosides from dried and nearly ripe fruits of Evodia rutaecarpa]. PubMed: Mosquito larvicidal activity of alkaloids and limonoids derived from Evodia rutaecarpa unripe fruits against Aedes albopictus (Diptera: Culicidae). PubMed: New cytotoxic quinolone alkaloids from fruits of Evodia rutaecarpa. PubMed: Evodiamine, a dual catalytic inhibitor of type I and II topoisomerases, exhibits enhanced inhibition against camptothecin resistant cells. PubMed: Pharmacokinetics and urine metabolite identification of dehydroevodiamine in the rat. PubMed: Comparative analysis of essential oil components of Evodia rutaecarpa (Juss.) Benth. var. officinalis (Dode) Huang and Evodia rutaecarpa (Juss.) Benth. PubMed: [Studies on preparation and dissolution test in vitro of intragastric floating two-chamber osmotic pump tablets of total alkaloids of Coptis chinensis and Evodia rutaecarpa]. PubMed: Induction of apoptosis by evodiamine involves both activation of mitotic arrest and mitotic slippage. PubMed: Effects of rutaecarpine on the metabolism and urinary excretion of caffeine in rats. PubMed: Evodiamine improves congnitive abilities in SAMP8 and APP(swe)/PS1(ΔE9) transgenic mouse models of Alzheimer's disease. PubMed: Optimization of extraction of evodiamine and rutaecarpine from fruit of Evodia rutaecarpa using modified supercritical CO(2). PubMed: Up-regulation of CYP1A1 by rutaecarpine is dependent on aryl hydrocarbon receptor and calcium. PubMed: Determination of dehydroevodiamine in Evodia rutaecarpa (Juss.) Benth by high performance liquid chromatography and classification of the samples by using hierarchical clustering analysis. PubMed: Rapid and preparative separation of traditional Chinese medicine Evodia rutaecarpa employing elution-extrusion and back-extrusion counter-current chromatography: comparative study. PubMed: Intragastric administration of evodiamine suppresses NPY and AgRP gene expression in the hypothalamus and decreases food intake in rats. PubMed: [Toxicological assessment on safety of water and 70% ethanolic extracts of nearly ripe fruit of Evodia rutaecarpa]. PubMed: Induction of NAD(P)H: quinone reductase by rutaecarpine isolated from the fruits of Evodia rutaecarpa in the murine hepatic Hepa-1c1c7 cell line. PubMed: Two new acylgluconic acids from the nearly ripe fruits of Evodia rutaecarpa. PubMed: [Study on oil-soluble components obtained from the fruit of Evoldia rutaecarpa]. PubMed: The effects of rutaecarpine on the pharmacokinetics of acetaminophen in rats. PubMed: Molecular authentication and quality control using a high performance liquid chromatography technique of Fructus Evodiae. PubMed: Inhibitory effect of rhetsinine isolated from Evodia rutaecarpa on aldose reductase activity. PubMed: A new limonoid from the fruits of Evodia rutaecarpa (Juss.) Benth. PubMed: Contents of constituents in mature and immature fruits of evodia species. PubMed: 6-Methoxy-N-methyl-1,2,3,4-tetrahydro-beta-carboline from Evodiae Fructus. PubMed: In vitro and in vivo antiallergic effect of the fructus of Evodia rutaecarpa and its constituents. PubMed: Studies on the alkaloid constituents of Evodia rutaecarpa (Juss) Benth var. bodinaieri (Dode) Huang and their acute toxicity in mice. PubMed: Quantitative analyses of indoloquinazoline alkaloids in Fructus Evodiae by high-performance liquid chromatography with atmospheric pressure chemical ionization tandem mass spectrometry. PubMed: Chemical and biological comparisons on Evodia with two related species of different locations and conditions. PubMed: Anti-inflammatory principles from the fruits of Evodia rutaecarpa and their cellular action mechanisms. PubMed: Development and validation of HPLC methods for the analysis of phenethylamine and indoloquinazoline alkaloids in Evodia species. PubMed: Anti-inflammatory activity in skin by biomimetic of Evodia rutaecarpa extract from traditional Chinese medicine. PubMed: Herb-drug interaction of Evodia rutaecarpa extract on the pharmacokinetics of theophylline in rats. PubMed: Mechanism-based inactivation of human liver microsomal CYP3A4 by rutaecarpine and limonin from Evodia fruit extract. PubMed: Evodiamine abolishes constitutive and inducible NF-kappaB activation by inhibiting IkappaBalpha kinase activation, thereby suppressing NF-kappaB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasion. PubMed: Protective effects of evodiamine on myocardial ischemia-reperfusion injury in rats. PubMed: [Studies on the chemical constituents of Evodia rutaecarpa (Juss.) Benth]. PubMed: Inhibition of leukotriene biosynthesis by quinolone alkaloids from the fruits of Evodia rutaecarpa. PubMed: Induction of cytochrome P450s by rutaecarpine and metabolism of rutaecarpine by cytochrome P450s. PubMed: Quinolone alkaloids with inhibitory activity against nuclear factor of activated T cells from the fruits of Evodia rutaecarpa. PubMed: Atypical apoptosis in L929 cells induced by evodiamine isolated from Evodia rutaecarpa. PubMed: [Advances in pharmacological study of Evodia rutaecarpa and its effective constituents]. PubMed: The nociceptive and anti-nociceptive effects of evodiamine from fruits of Evodia rutaecarpa in mice. PubMed: 1-methyl-2-undecyl-4(1H)-quinolone as an irreversible and selective inhibitor of type B monoamine oxidase. PubMed: Protective effects of calcitonin gene-related peptide-mediated evodiamine on guinea-pig cardiac anaphylaxis. PubMed: [Studies on the chemical constituents of Evodia rutaecarpa (Juss.) Benth. var. officinalis (Dode) Huang]. PubMed: [Assay of essential oil from Evodia rutaecarpa var. officinalis by GC/MS]. PubMed: Quinolone alkaloids, diacylglycerol acyltransferase inhibitors from the fruits of Evodia rutaecarpa. PubMed: Effects of evodiamine on gastrointestinal motility in male rats. PubMed: Evodia rutaecarpa protects against circulation failure and organ dysfunction in endotoxaemic rats through modulating nitric oxide release. PubMed: Capsaicin-like anti-obese activities of evodiamine from fruits of Evodia rutaecarpa, a vanilloid receptor agonist. PubMed: The positive inotropic and chronotropic effects of evodiamine and rutaecarpine, indoloquinazoline alkaloids isolated from the fruits of Evodia rutaecarpa, on the guinea-pig isolated right atria: possible involvement of vanilloid receptors. PubMed: Anti-diarrheal effect of water extract of Evodiae fructus in mice. PubMed: Cyclic adenosine monophosphate inhibits quinolone alkaloid evocarpine-induced apoptosis via activation of protein kinase A in human leukaemic HL-60 cells. PubMed: Highly selective antibacterial activity of novel alkyl quinolone alkaloids from a Chinese herbal medicine, Gosyuyu (Wu-Chu-Yu), against Helicobacter pylori in vitro. PubMed: A new class of COX-2 inhibitor, rutaecarpine from Evodia rutaecarpa. PubMed: Anti-Helicobacter pylori activity of quinolone alkaloids from Evodiae fructus. PubMed: Effect of evodiamine on catecholamine secretion from bovine adrenal medulla. PubMed: Antinociceptive activities of 70% methanol extract of evodiae fructus (fruit of Evodia rutaecarpa var. bodinieri) and its alkaloidal components. PubMed: Effect of the crude extract of Evodiae Fructus on the intestinal transit in mice. PubMed: Antianoxic action of evodiamine, an alkaloid in Evodia rutaecarpa fruit. PubMed: Uterotonic effect of Evodia rutaecarpa alkaloids. PubMed: [Studies on fatty acids from fruit and seed oils. 4. Analysis of the fatty acid composition in fruits of Evodia rutaecarpa of Chinese origin]. PubMed: [Isolation of hydroxyevodiamine (rhetsinine) from the fruits of Evodia rutaecarpa Hook fil. et Thomson].