Identification

Nameethyl isobutyrate
IUPACethyl 2-methylpropanoate
CAS Number97-62-1
EINECS202-595-4
FDA UNII9A9661LN4H
Molecular FormulaC6 H12 O2
Molecular Weight116.16004000
MDL NumberMFCD00009165
Nikkaji NumberJ3.222K
Beilstein0773846
CoE Number288

Regulatory

JECFA Food Flavoring186 ethyl isobutyrate
DG SANTE Food Flavourings09.413 ethyl isobutyrate
FEMA Number2428
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)97-62-1 ; ETHYL ISOBUTYRATE
FDA RegulationFDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION

Physical Properties

Appearance colorless clear liquid (est)
Assay 98.00 to 100.00
Food Chemicals Codex Listed Yes
Specific Gravity 0.86200 to 0.86800 @ 25.00 °C.
Pounds per Gallon - (est). 7.173 to 7.223
Refractive Index 1.38500 to 1.39100 @ 20.00 °C.
Melting Point -88.00 to -87.00 °C. @ 760.00 mm Hg
Boiling Point 112.00 to 113.00 °C. @ 760.00 mm Hg, 40.00 to 41.00 °C. @ 50.00 mm Hg
Acid Value 1.00 max. KOH/g
Vapor Pressure 25.400000 mmHg @ 25.00 °C.
Vapor Density 4.01 ( Air = 1 )
Flash Point 57.00 °F. TCC ( 13.89 °C. )
logP (o/w) 1.648 (est)
Shelf Life 12.00 month(s) or longer if stored properly.
Storage store in cool, dry place in tightly sealed containers, protected from heat and light.
Soluble in alcohol
Insoluble in water

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesperfuming agents

Organoleptic Properties

Odor Strength high ,
Substantivity 4 hour(s) at 100.00 %
Odor Description
at 10.00 % in dipropylene glycol.
Sweet, etherial and fruity with pungent, alcoholic, fusel and rummy nuances
Citrus, Buttery, Cherry, Strawberry
sweet, fruity, ethereal, with a rum like nuance
Fruity, sweet: Alcoholic: rum
Taste Description
at 12.50 ppm.
fruity, sweet
Fruity, pungent: rum

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Human Experience8 % solution: no irritation or sensitization.
Oral/Parenteral Toxicityoral-rat LD50 > 5000 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavor and fragrance agents
RIFM Fragrance Material Safety AssessmentSearch
Recommendation for ethyl isobutyrate usage levels up to8.0000 % in the fragrance concentrate.
Maximised Survey-derived Daily Intakes (MSDI-EU)640.00 (μg/capita/day)
baked goods-
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum-
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy-
fruit ices-
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

Advanced Biotech. Inc.

Inspired by Nature

A diverse range of products, all meeting our stringent commitment to quality.

View All Website 973-339-6242 info@adv-bio.com

Alfrebro LLC/ Archer Daniels Midland Company

Let's get reacquainted

Building great taste with aroma chemicals, extracts, and distillates

View All Website 513-539-7373 sforbis@alfrebro.com

Augustus Oils Ltd

The Premier Supplier

Augustus Oils Ltd, in harmony with nature - to present it at its best...

View All Website +44 (0)1420 590555 essentials@augustus-oils.ltd.uk

Axxence Aromatic GmbH

We bring nature to your flavour

Dedicated to provide the best possible quality and supply service of natural aroma ingredients.

View All Website +49.2822.68561.0 service@axxence.com

Beijing Lys Chemicals Co, LTD.

From Grams to Tons

Fine chemical high-tech company which contains R&D, production, and sales.

View All Website 86-10-68418738 jiayanyong@lyschem.com

Berje Inc.

Where the world comes to its senses

Where the world comes to its senses - Berjé is a global distributor of Essential Oils and Aromatic Chemicals.

View All Website 973-748-8980 tlauzurica@berjeinc.com

Charkit Chemical Corporation

The Specialty Chemical Specialists

Explore this website to discover the products and services that Charkit provides for your industry and please contact us directly to find out how we can be of service to you.

View All Website 203-299-3220 sales@charkit.com

Elan Inc.

Legacy of Innovation

Highest quality natural and synthetic products.

View All Website +86 021 57448053 (Elan Shanghai) dpimentel@elan-chemical.com

Excellentia International

Ingredients by Nature

Exceptional quality and excellence in meeting our customers requirements.

View All Website 732.749.9840 info@excellentiaint.com

Fleurchem, Inc.

Have A Flavorful Day

A leading global manufacturer and supplier of ingredients for Flavors, Fragrances, AromaTherapy, Foods, Beverages, Personal Care Products, and other uses.

View All Website 845-341-2100 info@fleurchem.com

Global Essence Inc.

Preferred Partner

Accommodate each customers unique needs.

View All Website 001 732 677 1100 info@globalessenceuk.com

H. Interdonati, Inc.

Innovative products

Because your flavors and fragrances are only as good as their source "Since 1952"

View All Website 800 367-6617 flavorplus@hinterdonati.com

FRUTAROM USA INC,

Flavor & Specialty Ingredients

Your preferred partner for flavour and fragrance success.

View All Website +44 (0) 1429 863 222 Sales.IFFIngredients@iff.com

Indukern, S.A. F&F Ingredients Division

Commitment to quality

Idukern F&F Ingredients is your partner for the fragrance and flavor ingredients.

View All Website +34 93 506 91 00 info@indukern.es

Jiangyin Healthway International Trade Co., Ltd

Independent Ingredients Supplier

We provide custom synthesis and contract manufacturing from milligrams to metric tonnes.

View All Website 86-510-86023169 info@healthwaychem.com

Lluch Essence S.L.

A family company dedicated to sales and distribution

Flexibility, availability, price and quality.

View All Website 34 93 379 38 49 web@lluche.com

M&U International LLC

Steady supply & demand

Meeting customers increasing demands at home as well as abroad.

View All Website 908-359-9000 sales@mu-intel.com

Moellhausen S.P.A.

THE CHEMISTRY OF EMOTIONS

Innovation and commitment in the name of excellence.

View All Website +39 039.685.6262

Penta International Corporation

Chemistry innovation

At Penta, our products and services help businesses do business better.

View All Website (973) 740-2300 lisaa@pentamfg.com

Robertet, Inc.

HOME OF NATURE, SEED TO SCENT

HOME OF NATURE – natural ingredients from the source.

View All Website +1.201.337.7100 info@robertetUSA.com

Sigma-Aldrich

Complete Supply Chain

The perfect blend of products and services that bring your creativity to life.

View All Website 800-244-1173 ff@sial.com

SRS Aromatics Ltd

For over 25 years

Bringing flavour and fragrance into your world.

View All Website +44 (0) 1284 704076 info@srsaromatics.co.uk

Sunaux International

Buy With Confidence

We have industry leading processes and procedures to ensure nothing but the most reliable product.

View All Website 0512-57995626 johnjft@sunaux.com

Taytonn ASCC Pte Ltd

Supplying Asia Pacific

We fully understand the demands of the F&F industry and we endeavour to supply quality products, with ready availability and a personalised service.

View All Website + 65 - 6861 8113 info@taytonnascc.com

TCI AMERICA

Moving Your Chemistry Forward

We continuously strive to advance our technology.

View All Website 1-800-423-8616 Sales-US@TCIchemicals.com;

R C Treatt and Co Ltd

Innovative ingredient solutions

World-leading innovative ingredient solutions provider for the flavour, fragrance and FMCG industries.

View All Website +1 863 668 9500 enquiries@treatt.com

Ernesto Ventós S.A.

Leaders in essence

We employ our five senses to do our job well.

View All Website +1 856 226 7501 info@ventos.com

Vigon International

Passion for Simplicity

Manufacturer and supplier of high quality flavor and fragrance ingredients.

View All Website 570-476-6300 sales@vigon.com

WholeChem, LLC

Connecting Innovators To the Building Blocks Of the Universe

Custom manufacturer and distributor of specialty ingredients. We make global local.

View All Website +1 (262) 995.8668 info@wholechem.com

Potential Uses

FR apple FR apricot FR banana FL beer FR berry FR blackberry FR cherry FL egg nog FR grape FR honey FR kiwi FR mango FR pear FR pineapple FR raspberry FR saffron FR strawberry FL/FR valerian FR wine

Natural Occurrence

apple fruit apple juice PMC apricot fruit bay laurel leaf beer PMC chamomile oil @ trace% Data fig fruit grape concord grape PMC honey PMC kiwi fruit lychee canned lychee mango fruit molasses PMC olive pineapple fruit quince fruit rum PMC spearmint oil strawberry juice wine port wine

Synonyms

iso butyric acid ethyl ester iso butyric acid ethylester iso butyric acid, ethyl ester ethyl 2-methyl propanoate ethyl 2-methyl propionate ethyl 2-methylpropanoate ethyl 2-methylpropionate ethyl 2,2-dimethyl acetate ethyl 2,2-dimethylacetate ethyl iso butyrate ethyl isobutanoate nat. ethyl isobutyrate ethyl isobutyrate 99%, (naturals) ethyl isobutyrate FCC ethyl isobutyrate FCC natural ethyl isobutyrate natural ethyl isobutyrate, natural ethyl methylpropanoate ethyl-iso-butyrate FCC ethylisobutyrate 2- methyl propanoic acid ethyl ester 2- methyl propionic acid ethyl ester 2- methylpropanoic acid ethyl ester propanoic acid, 2-methyl ethyl ester propanoic acid, 2-methyl-, ethyl ester propionic acid, 2-methyl-, ethyl ester Info: Volatile Flavor Components in Bogyojosaeng and Suhong Cultivars of Strawberry (Fragaria ananassa Duch.) PubMed: In situ Metabolic Characteristic Analysis Reveals the Key Yeast in the Spontaneous and Solid-state Fermentation Process of Chinese Light-style Liquor. J-Stage: Comparative Volatile Profiles in Soy Sauce According to Inoculated Microorganisms PubMed: Comparative volatile profiles in soy sauce according to inoculated microorganisms. J-Stage: Recyclable Polymeric p-Acid Catalyst Effective on Mannich-Type Reaction in Water PubMed: Potential aromatic compounds as markers to differentiate between Tuber melanosporum and Tuber indicum truffles. J-Stage: Odor-Active Constituents in Fresh Pineapple (Ananas comosus [L.] Merr.) by Quantitative and Sensory Evaluation PubMed: Influence of phenolic compounds on the sensorial perception and volatility of red wine esters in model solution: an insight at the molecular level. PubMed: Poly[tri(ethylene glycol) ethyl ether methacrylate]-coated surfaces for controlled fibroblasts culturing. PubMed: Airborne molds and bacteria, microbial volatile organic compounds (MVOC), plasticizers and formaldehyde in dwellings in three North European cities in relation to sick building syndrome (SBS). PubMed: Characterization of the major odor-active compounds in Thai durian ( Durio zibethinus L. 'Monthong') by aroma extract dilution analysis and headspace gas chromatography-olfactometry. PubMed: Identification of aroma-active compounds in Jiashi muskmelon juice by GC-O-MS and OAV calculation. PubMed: Automated ARGET ATRP Accelerates Catalyst Optimization for the Synthesis of Thiol-Functionalized Polymers. PubMed: Comparative metabolic profiling to investigate the contribution of O. oeni MLF starter cultures to red wine composition. PubMed: Main odorants in Jura flor-sherry wines. Relative contributions of sotolon, abhexon, and theaspirane-derived compounds. PubMed: Experience influences elemental and configural perception of certain binary odour mixtures in newborn rabbits. PubMed: A novel attractant for Anastrepha ludens (Diptera: Tephritidae) from a Concord grape product. PubMed: Proportion of odorants impacts the configural versus elemental perception of a binary blending mixture in newborn rabbits. PubMed: Comparison of fermented soybean paste (Doenjang) prepared by different methods based on profiling of volatile compounds. PubMed: Characterization of odor-active compounds in guava wine. PubMed: Responses of Rhynchophorus ferrugineus adults to selected synthetic palm esters: electroantennographic studies and trap catches in an urban environment. PubMed: Characterisation of the most odour-active compounds of bone tainted dry-cured Iberian ham. PubMed: Identification of odor impact compounds of Tagetes minuta L. essential oil: comparison of two GC-olfactometry methods. PubMed: Nitrogen addition influences formation of aroma compounds, volatile acidity and ethanol in nitrogen deficient media fermented by Saccharomyces cerevisiae wine strains. PubMed: Examples of perceptive interactions involved in specific "red-" and "black-berry" aromas in red wines. PubMed: Characterization of volatile compounds contributing to naturally occurring fruity fermented flavor in peanuts. PubMed: Defining the typical aroma of sherry vinegar: sensory and chemical approach. PubMed: Characterization of the key aroma compounds in an american bourbon whisky by quantitative measurements, aroma recombination, and omission studies. PubMed: Synthesis, alpha 1-adrenoceptor antagonist activity, and SAR study of novel arylpiperazine derivatives of phenytoin. PubMed: Characterization of the key aroma compounds in soy sauce using approaches of molecular sensory science. PubMed: Comparison of the odor-active compounds in unhopped beer and beers hopped with different hop varieties. PubMed: Quantification of selected aroma-active compounds in Pinot noir wines from different grape maturities. PubMed: Recyclable polymeric pi-acid catalyst effective on Mannich-type reaction in water. PubMed: Identification based on quantitative measurements and aroma recombination of the character impact odorants in a Bavarian Pilsner-type beer. PubMed: Odor-active constituents in fresh pineapple (Ananas comosus [L.] Merr.) by quantitative and sensory evaluation. PubMed: Aroma extract dilution analysis of cv. Meeker (Rubus idaeus L.) red raspberries from Oregon and Washington. PubMed: Identification of fruity/fermented odorants in high-temperature-cured roasted peanuts. PubMed: A study on volatile organic compounds (VOCs) produced by tropical ascomycetous yeasts. PubMed: Aroma extract dilution analysis of Cv. Marion (Rubus spp. hyb) and Cv. Evergreen (R. laciniatus L.) blackberries. PubMed: Chemical and sensorial aroma characterization of freshly distilled Calvados. 2. Identification of volatile compounds and key odorants. PubMed: Gas-phase reactivity of the O=P(OCH3)2+ phosphonium ion with aliphatic esters in a quadrupole ion trap. Spontaneous elimination of ketenes. PubMed: Evaluation of aroma differences between hand-squeezed juices from Valencia late and Navel oranges by quantitation of key odorants and flavor reconstitution experiments. PubMed: Evaluation of key aroma compounds in hand-squeezed grapefruit juice (Citrus paradisi Macfayden) by quantitation and flavor reconstitution experiments. PubMed: Volatile flavor components in red fermented soybean (Glycine max) curds. PubMed: Comparison of the most odor-active compounds in fresh and dried hop cones (Humulus lupulus L. variety spalter select) based on GC-olfactometry and odor dilution techniques. PubMed: Similarities in the aroma chemistry of Gewürztraminer variety wines and lychee (Litchi chinesis sonn.) fruit. PubMed: Total Synthesis of Bafilomycin A(1). PubMed: Ethyl propionate: Synergistic kairomone for african palm weevil,Rhynchophorus phoenicis L. (Coleoptera: Curculionidae). PubMed: Inhibition of lipogenesis in rat brown adipose tissue by clofibrate. PubMed: [Impact of odor hedonics on sensory odor intensity--physiological intensity and sensory intensity]. PubMed: Enhanced peroxisomal beta-oxidation of fatty acids and glutathione metabolism in rats exposed to phenoxyacetic acids. PubMed: Hypolipidemia and peroxisome proliferation induced by phenoxyacetic acid herbicides in rats. PubMed: Xanthone analogues of clofibrate / Synthesis and biological evaluation as antagonists of lipolysis in vitro. PubMed: The mouse as a model for evaluation of hypotriglyceridemic drugs effects of nicotinic acid, clofibrate and ethyl 2-(4-dibenzofuranyloxy)-2-methylpropionate on plasma lipoproteins. PubMed: The spontaneously hyperlipidemic old rat as a model for evaluation of hypolipoproteinemic drugs. Effects of nicotinic acid, clofibrate and ethyl 2-(4-dibenzofuranyloxy)-2-methylpropionate on plasma lipoproteins. PubMed: Larval osmeterial secretions of the swallowtails (Papilio). PubMed: [On the uricosuric activity of etofylline clofibrate (author's transl)]. PubMed: [Therapeutic experiences in the treatment of hyperlipoproteinaemia with etofylline clofibrate (author's transl)]. PubMed: [Effect of etofylline clofibrate on the composition of lipoproteins in hyperlipidaemia type IIb and IV (author's transl)]. PubMed: [On the effect of etofylline clofibrate on serum lipids and lipoproteins in patients with hyperlipoproteinemia of various degrees (author's transl)]. PubMed: [Clinical effects and tolerance of etofylline clofibrate]. PubMed: [Metabolism and pharmacokinetics of etofylline clofibrate, new antilipemic]. PubMed: Effect of etofylline clofibrate on experimental thrombosis and platelet function. PubMed: [Evaluation of the antilipaemic potential of etofylline clofibrate, its metabolites and clofibrate in dietary-induced hyperlipidaemia in the rat (author's transl)]. PubMed: Evaluation of the hypolipaemic activity of etofylline clofibrate, a new ester of etofylline and clofibric acid, and comparison with effects of known hypolipaemic agents. PubMed: Hypolipaemic activity of 1-(theophyllin-7-yl)-ethyl-2-[2-(p-chlorophenoxy)-2-methylpropionate] (etofylline clofibrate) and its analogues in normolipaemic rats. PubMed: [Pharmacology and toxicology of etofylline clofibrate]. PubMed: Biopharmaceutic evaluation of etofylline clofibrate and its drug formulation. PubMed: Clofibrate-induced increase in coenzyme A concentration in rat tissues. PubMed: Potential hypolipidemic agents. XVII. Synthesis and plasma lipid-lowering properties of compounds related to ethyl 2-(4-dibenzofuranyloxy)-2-methylpropionate and ethyl 2-(4-chlorophenoxy)-2-methylpropionate. PubMed: 1-(Theophyllin-7-yl)-ethyl-2-[2-(p-chlorophenoxy)-2-methylpropionate] (ML 1024), a new hypolipemic agent. PubMed: Potential hypolipidemic agents. XIV. Synthesis and plasma lipid-lowering properties of substituted biphenyls, diphenyl ethers and benzofurans related to ethyl 2-(4-dibenzofuranyloxy)-2-methylpropionate. PubMed: Hypolipemic activity of clofibrate-related compounds. PubMed: Increase in hepatic catalase and glycerol phosphate dehydrogenase activities on administration of clofibrate and clofenapate to the rat. PubMed: Ethyl-2-(p-chlorophenoxy)-2-methylpropionate (clofibrate) in experimental fat embolism in rats.