tebufenpyrad

1H-pyrazole-5-carboxamide, 4-chloro-N-((4-(1,1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-

CAS: 119168-77-3 C18 H24 Cl N3 O MW: 333.86148000

Identification

Nametebufenpyrad
IUPACN-[(4-tert-butylphenyl)methyl]-4-chloro-5-ethyl-2-methylpyrazole-3-carboxamide
CAS Number119168-77-3
FDA UNIIIRU3P7ZB3F
Molecular FormulaC18 H24 Cl N3 O
Molecular Weight333.86148000
MDL NumberMFCD01632408
Nikkaji NumberJ364.797H
Beilstein8636471

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 61.50 °C. @ 760.00 mm Hg
Boiling Point 468.40 °C. @ 760.00 mm Hg (est)
Flash Point 459.00 °F. TCC ( 237.10 °C. ) (est)
logP (o/w) 4.610
Soluble in water, 2.6 mg/L @ 25 °C (exp)

No sensory data available

Safety Information

Oral/Parenteral Toxicityoral-mouse LD50 210 mg/kg
Dermal Toxicityskin-rat LD50 > 2000 mg/kg
Inhalation Toxicityinhalation-rat LC50 2660 mg/m3

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryherbicides / pesticides
Recommendation for tebufenpyrad usage levels up tonot for fragrance use.
Recommendation for tebufenpyrad flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

N-(4-t- butylbenzyl)-4-chloro-3-ethyl-1-methylpyrazole-5-carboxamide N-[(4-tert- butylphenyl)methyl]-4-chloro-5-ethyl-2-methylpyrazole-3-carboxamide 4- chloro-N-((4-(1,1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide MK 239 MK239 pyranica 1H- pyrazole-5-carboxamide, 4-chloro-N-((4-(1,1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl- PubMed: The effect of mitochondrial complex I inhibitor on longevity of short-lived and long-lived seed beetles and its mitonuclear hybrids. PubMed: Determination of 28 pesticides applied on two tomato cultivars with a different surface/weight ratio of the berries, using a multiresidue GC-MS/MS method. PubMed: [Professional risk assessment for modern pesticides during their application in the horticulture]. PubMed: Ecotoxicity of binary mixtures of Microcystis aeruginosa and insecticides to Daphnia pulex. PubMed: Design, synthesis, and insecticidal evaluation of new pyrazole derivatives containing imine, oxime ether, oxime ester, and dihydroisoxazoline groups based on the inhibitor binding pocket of respiratory complex I. PubMed: [Determination of ten pesticides of pyrazoles and pyrroles in tea by accelerated solvent extraction coupled with gas chromatography-tandem mass spectrometry]. PubMed: Evidence of the in vitro genotoxicity of methyl-pyrazole pesticides in human cells. PubMed: A QuEChERS-based extraction method for the residual analysis of pyraclofos and tebufenpyrad in perilla leaves using gas chromatography: application to dissipation pattern. PubMed: Resistance to acaricides in Italian strains of Tetranychus urticae: toxicological and enzymatic assays. PubMed: Design, synthesis, and insecticidal activity of novel pyrazole derivatives containing α-hydroxymethyl-N-benzyl carboxamide, α-chloromethyl-N-benzyl carboxamide, and 4,5-dihydrooxazole moieties. PubMed: Ultraviolet radiation increases sensitivity to pesticides: synergistic effects on population growth rate of Daphnia magna at low concentrations. PubMed: [Acute tebufenpyrad and tolfenpyrad poisoning in humans]. PubMed: Rate of loss of insecticides during soil solarization and soil biosolarization. PubMed: Multi-residue analysis of 30 currently used pesticides in fine airborne particulate matter (PM 2.5) by microwave-assisted extraction and liquid chromatography-tandem mass spectrometry. PubMed: Synthesis of fully substituted pyrazoles via regio- and chemoselective metalations. PubMed: The discovery of HNPC-A3066: a novel strobilurin acaricide. PubMed: Synthesis of new fluorinated Tebufenpyrad analogs with acaricidal activity through regioselective pyrazole formation. PubMed: Resistance mechanisms to mitochondrial electron transport inhibitors in a field-collected strain of Tetranychus urticae Koch (Acari: Tetranychidae). PubMed: Improved regioselectivity in pyrazole formation through the use of fluorinated alcohols as solvents: synthesis and biological activity of fluorinated tebufenpyrad analogs. PubMed: Efficacy of five selected acaricides against Tetranychus urticae (Acari: Tetranychidae) and their side effects on relevant natural enemies occurring in citrus orchards. PubMed: Potential of 11 pesticides to initiate downstream drift of stream macroinvertebrates. PubMed: Toxicity of bifenazate and its principal active metabolite, diazene, to Tetranychus urticae and Panonychus citri and their relative toxicity to the predaceous mites, Phytoseiulus persimilis and Neoseiulus californicus. PubMed: Capabilities of different liquid chromatography tandem mass spectrometry systems in determining pesticide residues in food. Application to estimate their daily intake. PubMed: Multiple resistance and biochemical mechanisms of pyridaben resistance in Tetranychus urticae (Acari: Tetranychidae). PubMed: Sublethal effects of tebufenpyrad on the eggs and immatures of two-spotted spider mite, Tetranychus urticae. PubMed: Routine application using single quadrupole liquid chromatography-mass spectrometry to pesticides analysis in citrus fruits. PubMed: Disposable biosensor test for organophosphate and carbamate insecticides in milk. PubMed: Comparison of liquid chromatography using triple quadrupole and quadrupole ion trap mass analyzers to determine pesticide residues in oranges. PubMed: Comparative acaricide susceptibility and detoxifying enzyme activities in field-collected resistant and susceptible strains of Tetranychus urticae. PubMed: Fenpyroximate resistance in Tetranychus urticae (Acari: Tetranychidae): cross-resistance and biochemical resistance mechanisms. PubMed: Liquid chromatography-electrospray quadrupole ion-trap mass spectrometry of nine pesticides in fruits. PubMed: Application of liquid chromatography with electrospray tandem mass spectrometry to the determination of a new generation of pesticides in processed fruits and vegetables. PubMed: Evaluation of three concentrations of tebufenpyrad for the control of Varroa destructor (Acari: Varroidae). PubMed: The stability of tebufenpyrad resistance in two-spotted spider mite (Acari: Tetranychidae) under laboratory conditions. PubMed: New developments in insecticide resistance in the glasshouse whitefly (Trialeurodes vaporariorum) and the two-spotted spider mite (Tetranychus urticae) in the UK. PubMed: Cross-resistance, inheritance, and biochemistry of mitochondrial electron transport inhibitor-acaricide resistance in Tetranychus urticae (Acari: Tetranychidae). PubMed: Incidence and inheritance of resistance to METI-acaricides in European strains of the two-spotted spider mite (Tetranychus urticae) (Acari: Tetranychidae). PubMed: A laboratory-based method to measure relative pesticide and spray oil efficacy against broad mite, Polyphagotarsonemus latus (Banks)(Acari: Tarsonemidae).