mefenamic acid

anthranilic acid, N-2,3-xylyl-

CAS: 61-68-7 C15 H15 N O2 MW: 241.28995000

Identification

Namemefenamic acid
IUPAC2-(2,3-dimethylanilino)benzoic acid
CAS Number61-68-7
EINECS200-513-1
FDA UNII367589PJ2C
Molecular FormulaC15 H15 N O2
Molecular Weight241.28995000
MDL NumberMFCD00051721
Nikkaji NumberJ2.344B
Beilstein2216243
XlogP35.10 (est)

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 230.00 °C. @ 760.00 mm Hg
Boiling Point 398.80 °C. @ 760.00 mm Hg (est)
Flash Point 383.00 °F. TCC ( 195.00 °C. ) (est)
logP (o/w) 5.120
Soluble in water, 20 mg/L @ 30 °C (exp)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityintravenous-cat LD50 100 mg/kg
Dermal Toxicitysubcutaneous-mouse LDLo > 2000 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements', 'BEHAVIORAL: ATAXIA\nBEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)\nLUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION']

Safety in Use

Categorypharmaceuticals / chemical synthisis
Recommendation for mefenamic acid usage levels up tonot for fragrance use.
Recommendation for mefenamic acid flavor usage levels up tonot for flavor use.

BOC Sciences

Best of Chemicals Supplier

Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...

View All Website 1-631-485-4226 account@bocsci.com

Glentham Life Sciences Ltd

The Chemical, Biochemical & Research Essentials Supplier

Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK.

View All Website +44 (0) 1225 667798 info@glentham.com

TCI AMERICA

Moving Your Chemistry Forward

We continuously strive to advance our technology.

View All Website 1-800-423-8616 Sales-US@TCIchemicals.com;

Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

acidum mefenamicum anthranilic acid, N-(2,3-xylyl)- anthranilic acid, N-2,3-xylyl- bafameritin-M bafhameritin-M benzoic acid, 2-((2,3-dimethylphenyl)amino)- benzoic acid, 2-(2,3-dimethylphenyl)amino- bonabol CI-473 CL 473 CN 35355 CN-35355 coslan 2-(2,3- dimethylanilino)benzoic acid 2-((2,3- dimethylphenyl)amino)benzoic acid N-(2,3- dimethylphenyl)anthranilic acid 2- diphenylaminecarboxylic acid, 2',3'-dimethyl- fenamin lysalgo mefacit mefedolo mefenamate mephenamic acid mephenaminic acid methenamic acid mycasaal namphen parkemed ponalar ponstan ponstan forte ponstel rolan tanston vialidon N-(2,3- xylyl)-2-aminobenzoic acid N-2,3- xylylanthranilic acid PubMed: Synthesis, structure and biological activity of nickel(II) complexes with mefenamato and nitrogen-donor ligands. PubMed: Multi-residue analytical methodology-based liquid chromatography-time-of-flight-mass spectrometry for the analysis of pharmaceutical residues in surface water and effluents from sewage treatment plants and hospitals. PubMed: The determination of pharmaceutical residues in cooked and uncooked marine bivalves using pressurised liquid extraction, solid-phase extraction and liquid chromatography–tandem mass spectrometry. PubMed: Validation of a liquid chromatography method for the simultaneous determination of several nonsteroidal anti-inflammatory drugs in human plasma for therapeutic drug monitoring. PubMed: The determination of pharmaceutical residues in cooked and uncooked marine bivalves using pressurised liquid extraction, solid-phase extraction and liquid chromatography-tandem mass spectrometry. PubMed: Development and validation of a confirmatory method for the determination of 12 non steroidal anti-inflammatory drugs in milk using liquid chromatography-tandem mass spectrometry. PubMed: Simultaneous determination of 20 pharmacologically active substances in cow's milk, goat's milk, and human breast milk by gas chromatography-mass spectrometry. PubMed: A wild blueberry-enriched diet (Vaccinium angustifolium) improves vascular tone in the adult spontaneously hypertensive rat. PubMed: Confirmatory analysis of non-steroidal anti-inflammatory drugs in bovine milk by high-performance liquid chromatography with fluorescence detection. PubMed: Dietary enrichment with wild blueberries (Vaccinium angustifolium) affects the vascular reactivity in the aorta of young spontaneously hypertensive rats. PubMed: Confirmatory identification of sixteen non-steroidal anti-inflammatory drug residues in raw milk by liquid chromatography coupled with ion trap mass spectrometry. PubMed: Inhibition of sulfotransferases by xenobiotics. PubMed: Determination of glabridin in human plasma by solid-phase extraction and LC-MS/MS. PubMed: The "high solubility" definition of the current FDA Guidance on Biopharmaceutical Classification System may be too strict for acidic drugs. PubMed: [Variance of bioavailability of pharmaceutical preparations and analysis of factors affecting it]. PubMed: In vivo selectivity of nonsteroidal antiinflammatory drugs and gastrointestinal ulcers in rats. PubMed: [In vivo selectivity of nonsteroidal anti-inflammatory drugs on COX-1-COX-2 and gastrointestinal ulcers, in rats]. PubMed: Experimental renal papillary necrosis in the Syrian hamster. PubMed: Thromboxane synthesis inhibitors and postprandial jejunal capillary exchange capacity. PubMed: Effects of food on absorption of mefenamic acid from two commercial capsules differing in bioavailability under the fasting state. PubMed: Bioavailability of mefenamic acid: influence of food and water intake. PubMed: The effects of mefenamic acid on postprandial intestinal carbohydrate metabolism. PubMed: Prostaglandin synthesis inhibition and postprandial intestinal hyperemia.