Identification

Namemethyl ethyl ketone
IUPACbutan-2-one
CAS Number78-93-3
EINECS201-159-0
FDA UNII6PT9KLV9IO
Molecular FormulaC4 H8 O
Molecular Weight72.10696000
MDL NumberMFCD00011648
Nikkaji NumberJ1.960G
Beilstein0741880
CoE Number753
XlogP30.30 (est)

Regulatory

JECFA Food Flavoring278 2-butanone
JECFA Food AdditiveEthyl Methyl Ketone
DG SANTE Food Flavourings07.053 butan-2-one
FEMA Number2170
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)78-93-3 ; 2-BUTANONE
FDA RegulationFDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION

Physical Properties

Appearance colorless clear liquid (est)
Assay 99.50 to 100.00
Food Chemicals Codex Listed Yes
Specific Gravity 0.80100 to 0.80300 @ 25.00 °C.
Pounds per Gallon - (est). 6.665 to 6.682
Refractive Index 1.37700 to 1.38000 @ 20.00 °C.
Melting Point -85.00 to -87.00 °C. @ 760.00 mm Hg
Boiling Point 78.60 to 80.00 °C. @ 760.00 mm Hg
Acid Value 2.00 max. KOH/g
Vapor Pressure 90.600000 mmHg @ 25.00 °C.
Vapor Density 2.49 ( Air = 1 )
Flash Point 26.00 °F. TCC ( -3.33 °C. )
logP (o/w) 0.290
Soluble in alcohol

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesperfuming agents

Organoleptic Properties

Odor Description
at 1.00 % in dipropylene glycol.
Etherial, diffusive and slightly fruity with a camphoreous nuance
Taste Description at 5.00 ppm.

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Oral/Parenteral Toxicityoral-rat LD50 [sex: M] 5490 mg/kg
Dermal Toxicityskin-rabbit LD50 6480 mg/kg
Inhalation Toxicityinhalation-muskrat LC50 32 gm/M3/4hour

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryextraction solvents, flavoring agents
RIFM Fragrance Material Safety AssessmentSearch
Recommendation for methyl ethyl ketone usage levels up to0.5000 % in the fragrance concentrate.
Maximised Survey-derived Daily Intakes (MSDI-EU)96.00 (μg/capita/day)
baked goods-
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum-
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy-
fruit ices-
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

Advanced Biotech. Inc.

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Alfrebro LLC/ Archer Daniels Midland Company

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Potential Uses

FL banana FL bread white bread FL carrot FL cheese cheddar cheese FL cheese swiss cheese FL coffee FL cream FL dairy FL fish FL grape solvents FL tea black tea FL tomato FL yogurt

Natural Occurrence

apple fruit apple fruit juice bread white bread PMC butter PMC cabbage leaf carrot cheese cheddar cheese PMC cheese swiss cheese PMC coffee PMC currant black currant fruit fish PMC guava fruit pear plant pepper bell pepper fruit peppermint oil plum fruit potato chip PMC tea black tea tea leaf tomato fruit truffle yogurt

Synonyms

acetylethane butan-2-one 2-oxo butane 2- butanone 2- butanone (methyl ethyl ketone) natural ethyl methyl cetone ethyl methyl ketone ethylmethyl ketone ethylmethylketone ketone C-4 ketone, ethyl methyl MEK methyl acetone methyl ethyl cetone methyl ethyl ketone, natural methyl propanal methyl-ethyl-ketone methylacetone methylethyl ketone methylethylketone Info: HEPTAN-2-ONE PubMed: Milk volatile organic compounds and fatty acid profile in cows fed timothy as hay, pasture, or silage. Info: Volatile Flavor Components in Bogyojosaeng and Suhong Cultivars of Strawberry (Fragaria ananassa Duch.) PubMed: Headspace volatile components of Canadian grown low-tannin faba bean (Vicia faba L.) genotypes. PubMed: Chemical characterization of commercial liquid smoke products. PubMed: Transcriptome profiling of heat-resistant strain Bacillus licheniformis CGMCC3962 producing Maotai flavor. PubMed: Scientific assessment of the use of sugars as cigarette tobacco ingredients: a review of published and other publicly available studies. PubMed: Volatile flavor compounds in yogurt: a review. PubMed: Ewe's diet (pasture vs grain-based feed) affects volatile profile of cooked meat from light lamb. PubMed: Chemical and biochemical study of industrially produced San Simón da Costa smoked semi-hard cow's milk cheeses: Effects of storage under vacuum and different modified atmospheres. PubMed: High-yield fermentative preparation of tetramethylpyrazine by Bacillus sp. using an endogenous precursor approach. PubMed: Solid-phase microextraction for the determination of volatile compounds in the spoilage of raw ground beef. PubMed: Prediction of sensory properties of Brazilian Arabica roasted coffees by headspace solid phase microextraction-gas chromatography and partial least squares. PubMed: Relationships between sensory descriptors, consumer acceptability and volatile flavor compounds of American dry-cured ham. PubMed: Effect of enhancement and ageing on flavor and volatile compounds in various beef muscles. PubMed: Instrumental and sensory characterization of heat-induced odorants in aseptically packaged soy milk. PubMed: Characterization of aroma-active compounds in raw and cooked pine-mushrooms (Tricholoma matsutake Sing.). PubMed: Aroma extract dilution analysis of cv. Meeker (Rubus idaeus L.) red raspberries from Oregon and Washington. PubMed: Proteolysis, volatile compounds, and sensory evaluation in Hispánico cheese manufactured with the addition of a thermophilic adjunct culture, nisin, and calcium alginate-nisin microparticles. PubMed: Modification of fatty acids changes the flavor volatiles in tomato leaves. PubMed: Significance of volatile compounds produced by spoilage bacteria in vacuum-packed cold-smoked salmon (Salmo salar) analyzed by GC-MS and multivariate regression. PubMed: Generation of odorous acyloins by yeast pyruvate decarboxylases and their occurrence in sherry and soy sauce. PubMed: Volatile flavor components of rice cakes. PubMed: Characterization of volatile compounds from the reaction of 3-hydroxy-2-butanone and ammonium sulfide model system. PubMed: Flavor and texture characteristics of low fat ground beef patties formulated with whey protein concentrate. PubMed: [The quantitative composition of natural and technologically changed aromas of plants. II. Aroma compounds in oranges and their changes during juice processing (author's transl)].