butyl amine
butylamine
Identification
| Name | butyl amine |
| IUPAC | butan-1-amine |
| CAS Number | 109-73-9 |
| EINECS | 203-699-2 |
| FDA UNII | N2QV60B4WR |
| Molecular Formula | C4 H11 N |
| Molecular Weight | 73.13867000 |
| MDL Number | MFCD00011690 |
| Nikkaji Number | J2.436H |
| Beilstein | 0605269 |
| CoE Number | 524 |
| XlogP3 | 1.00 (est) |
Regulatory
| JECFA Food Flavoring | 1582 butylamine |
| DG SANTE Food Flavourings | 11.003 butylamine |
| FEMA Number | 3130 |
| FDA | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF) | 109-73-9 ; BUTYLAMINE |
Physical Properties
| Appearance | colorless to yellow clear liquid (est) |
| Assay | 99.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Specific Gravity | 0.73200 to 0.74000 @ 25.00 °C. |
| Pounds per Gallon - (est). | 6.091 to 6.158 |
| Refractive Index | 1.39800 to 1.40400 @ 20.00 °C. |
| Melting Point | -49.00 °C. @ 760.00 mm Hg |
| Boiling Point | 77.00 to 78.00 °C. @ 760.00 mm Hg |
| Vapor Pressure | 92.900000 mmHg @ 25.00 °C. |
| Vapor Density | 2.5 ( Air = 1 ) |
| Flash Point | 30.00 °F. TCC ( -1.11 °C. ) |
| logP (o/w) | 0.930 |
| Soluble in | alcohol |
Organoleptic Properties
| Odor Description | at 0.10 % in propylene glycol. |
Safety Information
| Preferred SDS | View |
| European information | Most important hazard(s): |
| Oral/Parenteral Toxicity | oral-rat LD50 366 mg/kg |
| Dermal Toxicity | skin-rabbit LD50 850 ul/kg |
| Inhalation Toxicity | inhalation-mouse LC50 800 mg/m3/2H |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | flavoring agents |
| Recommendation for butyl amine usage levels up to | not for fragrance use. |
| Maximised Survey-derived Daily Intakes (MSDI-EU) | 89.00 (μg/capita/day) |
| Maximised Survey-derived Daily Intakes (MSDI-USA) | 0.01 (μg/capita/day) |
| Threshold of Concern | 1800 (μg/person/day) |
| Structure Class | I |
| baked goods | - |
| beverages(nonalcoholic) | - |
| beverages(alcoholic) | - |
| breakfast cereal | - |
| cheese | - |
| chewing gum | - |
| condiments / relishes | - |
| confectionery froastings | - |
| egg products | - |
| fats / oils | - |
| fish products | - |
| frozen dairy | - |
| fruit ices | - |
| gelatins / puddings | - |
| granulated sugar | - |
| gravies | - |
| hard candy | - |
| imitation dairy | - |
| instant coffee / tea | - |
| jams / jellies | - |
| meat products | - |
| milk products | - |
| nut products | - |
| other grains | - |
| poultry | - |
| processed fruits | - |
| processed vegetables | - |
| reconstituted vegetables | - |
| seasonings / flavors | - |
| snack foods | - |
| soft candy | - |
| soups | - |
| sugar substitutes | - |
| sweet sauces | - |
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Potential Uses
Natural Occurrence
Synonyms
1-
aminobutane
butan-1-amine
butanamine
1-
butanamine
mono-
butyl amine
N-
butyl amine
butyl-amine
butylamine
1-
butylamine
nor
valamine
Info:
aliphatic and aromatic amines and amides
PubMed:
Quantification of isocyanates and amines in polyurethane foams and coated products by liquid chromatography-tandem mass spectrometry.
PubMed:
Gas chromatography-mass spectrometry assessment of amines in Port wine and grape juice after fast chloroformate extraction/derivatization.
PubMed:
Determination of volatile nitrosamines in various meat products using comprehensive gas chromatography-nitrogen chemiluminescence detection.
PubMed:
Development and application of a method for analysis of phthalates in ham sausages by solid-phase extraction and gas chromatography-mass spectrometry.
PubMed:
A new ultra-pressure liquid chromatography method for the determination of biogenic amines in cheese.
PubMed:
Determination of aliphatic amines by cation-exchange chromatography with suppressed conductivity detection after solid phase extraction.
PubMed:
Synthesis of N-4-butylamine acridone and its use as fluorescent probe for ctDNA.
PubMed:
Olfactory responses in a gustatory organ of the malaria vector mosquito Anopheles gambiae.
PubMed:
Dermal, inhalation, and internal exposure to 1,6-HDI and its oligomers in car body repair shop workers and industrial spray painters.
PubMed:
Protection of originality of Tokaji Aszú: amines and organic acids in botrytized wines by high-performance liquid chromatography.
PubMed:
Synthesis of haptens and development of an immunoassay for the olive fruit fly pheromone.
PubMed:
Developmental toxicity of oral n-butylamine hydrochloride and inhaled n-butylamine in rats.
PubMed:
Maillard reaction of D-glucose: identification of a colored product with conjugated pyrrole and furanone rings.
PubMed:
Structure of green pigment formed by the reaction of caffeic acid esters (or chlorogenic acid) with a primary amino compound.
PubMed:
Reduction of tetrazolium salt XTT by aminoreductone formed during the Maillard reaction of lactose.
PubMed:
Effect of common food preservatives on mycelial growth and spore germination of Fusarium oxysporum.
PubMed:
Rapid semi-quantitative estimation of N-nitrosodibutylamine and N-nitrosodibenzylamine in smoked hams by solid-phase microextraction followed by gas chromatography-thermal energy analysis.
PubMed:
Quantitative determination of amines in wine by liquid chromatography.
PubMed:
Investigations on organ-specific metabolism and genotoxic effects of the urinary bladder carcinogen N-nitrosobutyl-3-carboxypropylamine (BCPN) and its analogs N-nitrosodibutylamine (NDBA) and N-nitrosobutyl-4-hydroxybutylamine (4-OH-NDBA).
PubMed:
Trapping of reactive intermediates from the nitrosation of primary amines by a new type of scavenger reagent.
PubMed:
Evaluation of organosolv processes for the fractionation and modification of corn stover for bioconversion.
PubMed:
Effect of butylated hydroxyanisole on in vitro and in vivo nitrosation of dibutylamine.
PubMed:
Possible underestimation of nitrosatable amine levels in artificial saliva extracts of children's rubber pacifiers and baby-bottle teats.
PubMed:
Correlations between skin sensitization potential and chemical reactivity for p-nitrobenzyl compounds.