choline dihydrogen citrate

2-hydroxy-N,N,N-trimethylethanaminium salt with 2-Hydroxy-1,2,3-propanetricarboxylic acid (1:1)

CAS: 77-91-8 C11 H21 N O8 MW: 295.28897000

Identification

Namecholine dihydrogen citrate
IUPAC2-(carboxymethyl)-2,4-dihydroxy-4-oxobutanoate;2-hydroxyethyl(trimethyl)azanium
CAS Number77-91-8
EINECS201-068-6
FDA UNIIDQ8HHP07GL
Molecular FormulaC11 H21 N O8
Molecular Weight295.28897000
MDL NumberMFCD00038734

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 106.00 °C. @ 760.00 mm Hg
Boiling Point 309.60 °C. @ 760.00 mm Hg (est)
Vapor Pressure 0.000057 mmHg @ 25.00 °C. (est)
Flash Point 311.00 °F. TCC ( 155.20 °C. ) (est)
logP (o/w) -1.721 (est)
Soluble in water, 1e+006 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityintraperitoneal-mouse LD50 > 4800 mg/kg
Dermal Toxicitysubcutaneous-mouse LD50 > 4800 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorypharmaceuticals / chemical synthisis
Recommendation for choline dihydrogen citrate usage levels up tonot for fragrance use.
Recommendation for choline dihydrogen citrate flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

2-( carboxymethyl)-2,4-dihydroxy-4-oxobutanoate; 2-hydroxyethyl-trimethylazanium 2-( carboxymethyl)-2,4-dihydroxy-4-oxobutanoate;2-hydroxyethyl(trimethyl)azanium cholex choline citrate (1:1) (salt) choline dihydrogen citrate conditioned choline dihydrogen citrate NF 12 choline dihydrogen citrate NF 12 treated choline dihydrogencitrate salt choline, citrate (1:1) (salt) cholinedihydrogencitratesalt cholinvel chothyn cirrocolina citracholin citrocholine citrocol colicitrin delichol ethanaminium, 2-hydroxy-N,N,N-trimethyl-, salt with 2-hydroxy-1,2,3-propanetricarboxylic acid 2- hydroxy-N,N,N-trimethylethanaminium 3-carboxy-2-(carboxymethyl)-2-hydroxypropanoate 2- hydroxy-N,N,N-trimethylethanaminium salt with 2-Hydroxy-1,2,3-propanetricarboxylic acid (1:1) neurotropan PubMed: Temporal B0 field variation effects on MRSI of the human prostate at 7 T and feasibility of correction using an internal field probe. PubMed: Non-invasive estimation of prostate cancer aggressiveness using diffusion-weighted MRI and 3D proton MR spectroscopy at 3.0 T. PubMed: Facilitating early recovery of bowel motility after colorectal surgery: a systematic review. PubMed: Treatment of postoperative ileus with choline citrate--results of a prospective, randomised, placebo-controlled, double-blind multicentre trial. PubMed: Tumor volume and metabolism of prostate cancer determined by proton magnetic resonance spectroscopic imaging at 3T without endorectal coil reveal potential clinical implications in the context of radiation oncology. PubMed: The effectiveness of choline citrate infusions monitored by lymphocyte transformation test (LTT) in multiple sclerosis. A new approach to the diagnosis and treatment of the disease. PubMed: Adult prostate sarcoma: radiological-clinical correlation. PubMed: Regarding the focal treatment of prostate cancer: inference of the Gleason grade from magnetic resonance spectroscopic imaging. PubMed: Application of the inverse Monte Carlo treatment planning system IKO for an inhomogeneous dose prescription in the sense of dose painting. PubMed: Combined use of diffusion-weighted MRI and 1H MR spectroscopy to increase accuracy in prostate cancer detection. PubMed: A proton NMR study of the effect of a new intravasal injectable male contraceptive RISUG on seminal plasma metabolites. PubMed: The effects of choline supplementation on physical performance. PubMed: Quantification by magnetic resonance spectroscopy of metabolites in seminal plasma able to differentiate different forms of azoospermia. PubMed: Methionine, choline and sulfate interrelationships in the diet of weanling swine. PubMed: Bioavailability of iron from ferric choline citrate and a ferric copper cobalt choline citrate complex for young pigs. PubMed: Effect of small intestinal bypass on hepatic lipid accumulation in rats. PubMed: Chemosensory responses by the heterotrophic marine dinoflagellateCrypthecodinium cohnii. PubMed: Use of ferric choline citrate in the prevention of iron-deficiency anemia in baby pigs. PubMed: Hemoglobin synthesis with iron choline citrate in hypochromic anemia of pregnancy. PubMed: Effect of injected choline citrate in experimental atherosclerosis. PubMed: [Effect of citrate and choline citrate on anaerobic synthesis of acetylcholine]. PubMed: [The effect of choline citrate on the carbohydrate metabolism]. PubMed: [Results with choline citrate therapy of inoperable cervical carcinoma]. PubMed: NEW and nonofficial remedies: choline dihydrogen citrate. PubMed: [Choline citrate].