laevo-limonene

L-limonene

CAS: 5989-54-8 C10 H16 MW: 136.23752000 terpenic terpenic

Identification

Namelaevo-limonene
IUPAC(4S)-1-methyl-4-prop-1-en-2-ylcyclohexene
CAS Number5989-54-8
EINECS227-815-6
FDA UNII47MAJ1Y2NE
Molecular FormulaC10 H16
Molecular Weight136.23752000
MDL NumberMFCD00001558
Nikkaji NumberJ85.992C
Beilstein2323991
CoE Number491

Regulatory

DG SANTE Food Flavourings01.046 L-limonene
FDA Mainterm (SATF)5989-54-8 ; L-LIMONENE
FDA RegulationFDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE

Physical Properties

Appearance colorless clear liquid (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed Yes
Specific Gravity 0.84400 to 0.84800 @ 15.00 °C.
Pounds per Gallon - (est). 7.037 to 7.071
Refractive Index 1.47100 to 1.47500 @ 20.00 °C.
Optical Rotation -118.0 to -108.0
Boiling Point 176.00 to 177.00 °C. @ 760.00 mm Hg
Vapor Pressure 1.541000 mmHg @ 25.00 °C. (est)
Vapor Density 4.7 ( Air = 1 )
Flash Point 127.00 °F. TCC ( 52.78 °C. )
logP (o/w) 4.380
Soluble in alcohol
Insoluble in water

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesperfuming agents

Organoleptic Properties

Odor Strength medium
Substantivity 4 hour(s) at 100.00 %
Odor Description
at 100.00 %.
POWERFUL, TERPENIC
Odor sample from CA Aromatics Company Inc.
Taste Description terpenic cilantro green juniper berry

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Oral/Parenteral Toxicityoral-rat LD50 5000 mg/kg
Dermal Toxicityskin-rabbit LD50 > 5000 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavor and fragrance agents
RIFM Fragrance Material Safety AssessmentSearch
IFRA Critical EffectDermal sensitization
IFRA Other Specification< 20 mmoles / liter peroxides
fragrance material specificationd-, l-and dl-Limonene and natural products containing substantial amounts of it, should only be used when the level of peroxides is kept to the lowest practical level, for instance by adding antioxidants at the time of production. Such products should have a peroxide value of less than 20 millimoles peroxides per liter, determined according to the FMA method, which can be downloaded from the IFRA website (see Analytical Methods).
Recommendation for laevo-limonene usage levels up to8.0000 % in the fragrance concentrate.
Maximised Survey-derived Daily Intakes (MSDI-EU)2100.00 (μg/capita/day)
Threshold of Concern1800 (μg/person/day)
Structure ClassI
Dairy products, excluding products of category 02.0 (01.0)3.00000
Fats and oils, and fat emulsions (type water-in-oil) (02.0)2.00000
Edible ices, including sherbet and sorbet (03.0)5.00000
Processed fruit (04.1)1.00000
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2)-
Confectionery (05.0)5.00000
Chewing gum (05.3)-
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0)2.00000
Bakery wares (07.0)5.00000
Meat and meat products, including poultry and game (08.0)1.00000
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0)1.00000
Eggs and egg products (10.0)1.00000
Sweeteners, including honey (11.0)1.00000
Salts, spices, soups, sauces, salads, protein products, etc. (12.0)2.00000
Foodstuffs intended for particular nutritional uses (13.0)3.00000
Non-alcoholic ("soft") beverages, excl. dairy products (14.1)2.00000
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2)4.00000
Ready-to-eat savouries (15.0)2.00000
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0)2.00000

Augustus Oils Ltd

The Premier Supplier

Augustus Oils Ltd, in harmony with nature - to present it at its best...

View All Website +44 (0)1420 590555 essentials@augustus-oils.ltd.uk

Berje Inc.

Where the world comes to its senses

Where the world comes to its senses - Berjé is a global distributor of Essential Oils and Aromatic Chemicals.

View All Website 973-748-8980 tlauzurica@berjeinc.com

BOC Sciences

Best of Chemicals Supplier

Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...

View All Website 1-631-485-4226 account@bocsci.com

ECSA Chemicals

Human Chemistry

ECSA Chemicals has been active since 1913 in the trading and international commerce of raw materials. With an organisation divided into industrial segments managed by specialists, it has become one of...

View All Website +41 91 695 88 00 marketing@ecsa.ch

Excellentia International

Ingredients by Nature

Exceptional quality and excellence in meeting our customers requirements.

View All Website 732.749.9840 info@excellentiaint.com

Fleurchem, Inc.

Have A Flavorful Day

A leading global manufacturer and supplier of ingredients for Flavors, Fragrances, AromaTherapy, Foods, Beverages, Personal Care Products, and other uses.

View All Website 845-341-2100 info@fleurchem.com

Foreverest Resources Ltd.

Leading pine based chemicals supplier

Supplying turpentine based and natural/extracted flavor & fragrance ingredients.

View All Website +86 (0)592 5105533 info@foreverest.cn

Global Essence Inc.

Preferred Partner

Accommodate each customers unique needs.

View All Website 001 732 677 1100 info@globalessenceuk.com

Indukern, S.A. F&F Ingredients Division

Commitment to quality

Idukern F&F Ingredients is your partner for the fragrance and flavor ingredients.

View All Website +34 93 506 91 00 info@indukern.es

Lluch Essence S.L.

A family company dedicated to sales and distribution

Flexibility, availability, price and quality.

View All Website 34 93 379 38 49 web@lluche.com

Moellhausen S.P.A.

THE CHEMISTRY OF EMOTIONS

Innovation and commitment in the name of excellence.

View All Website +39 039.685.6262

Penta International Corporation

Chemistry innovation

At Penta, our products and services help businesses do business better.

View All Website (973) 740-2300 lisaa@pentamfg.com

Sigma-Aldrich

Complete Supply Chain

The perfect blend of products and services that bring your creativity to life.

View All Website 800-244-1173 ff@sial.com

SRS Aromatics Ltd

For over 25 years

Bringing flavour and fragrance into your world.

View All Website +44 (0) 1284 704076 info@srsaromatics.co.uk

TCI AMERICA

Moving Your Chemistry Forward

We continuously strive to advance our technology.

View All Website 1-800-423-8616 Sales-US@TCIchemicals.com;

The John D. Walsh Company, Inc

Suppliers Since 1942

Supplying the fragrance and flavor industry with high quality products.

View All Website 973-962-1400 info@johndwalsh.com

R C Treatt and Co Ltd

Innovative ingredient solutions

World-leading innovative ingredient solutions provider for the flavour, fragrance and FMCG industries.

View All Website +1 863 668 9500 enquiries@treatt.com

Ernesto Ventós S.A.

Leaders in essence

We employ our five senses to do our job well.

View All Website +1 856 226 7501 info@ventos.com

Potential Uses

FR acacia FR apple green apple FR bergamot FL/FR cajeput FR citrus FR cologne FR evergreen FR fir balsam FR fir needle oil replacer FR green grass FR herbal FR lavender FR mandarin FR mint FR neroli FR orange blossom FR peppermint FR pine FR pineapple FR rain FR spearmint FL/FR turpentine FR wormseed oil replacer

Natural Occurrence

anise star anise anise star anise fruit cajuput caraway seed oil cardamom seed oil copal congo copal resin PMC cornmint leaf cotton plant dill oil dill seed oil fennel seed horsemint pepper black pepper fruit pepper black pepper seed peppermint leaf pine needle oil PMC sage spearmint spearmint leaf spearmint oil spearmint plant tea tree oil australia @ trace% Data water mint leaf wormseed american

Synonyms

cyclohexene, 1-methyl-4-(1-methylethenyl)-, (4S)- cyclohexene, 1-methyl-4-(1-methylethenyl)-, (S)- (-)- limonene (-)-(4S)- limonene (-)-(S)- limonene (4S)- limonene (4S)-(-)- limonene (S)- limonene (S)-(-)- limonene beta- limonene L- limonene L- limonene - 65 L- limonene - 80 laevo- limonene (natural) laevo- limonene 75° limonene L-65 limonene L-70 L- limonene natural laevo- limonene natural L- limonene, natural (S)-(-)-p- mentha-1,8-diene (S)-(-)-para- mentha-1,8-diene (S)-p- mentha-1,8-diene p- mentha-1,8-diene, (S)-(-)- (4S)-1- methyl-4-(1-methyl ethenyl) cyclohexene (S)-1- methyl-4-(1-methyl ethenyl) cyclohexene (S)-1- methyl-4-(1-methyl vinyl) cyclohexene (4S)-1- methyl-4-(1-methylethenyl)cyclohexene (S)-1- methyl-4-(1-methylethenyl)cyclohexene (S)-1- methyl-4-(1-methylvinyl)cyclohexene (4S)-1- methyl-4-(prop-1-en-2-yl)cyclohex-1-ene (4S)-1- methyl-4-(prop-1-en-2-yl)cyclohexene (4S)-1- methyl-4-isopropenylcyclohex-1-ene (4S)-1- methyl-4-prop-1-en-2-ylcyclohexene (S)-4-iso propenyl-1-methyl cyclohexene (4S)-4-iso propenyl-1-methylcyclohexene (S)-(-)-4-iso propenyl-1-methylcyclohexene Info: Limonene PubMed: Capturing of the monoterpene olefin limonene produced in Saccharomyces cerevisiae. PubMed: Chemical composition and anti-inflammation activity of essential oils from Citrus unshiu flower. PubMed: Differential mechanism of Escherichia coli Inactivation by (+)-limonene as a function of cell physiological state and drug's concentration. PubMed: In vitro evaluation of dill seed essential oil antifungal activities to control Zymoseptoria tritici. PubMed: Antioxidant and anticarcinogenic effects of methanolic extract and volatile oil of fennel seeds (Foeniculum vulgare). PubMed: Acaricidal and quantitative structure activity relationship of monoterpenes against the two-spotted spider mite, Tetranychus urticae. PubMed: Larvicidal effects of the major essential oil of Pittosporum tobira against Aedes aegypti (L.). PubMed: Odor detection and odor discrimination in subadult and adult rats for two enantiomeric odorants supported by c-fos data. PubMed: [Analysis of volatile components in Qingshanlvshui tea using solid-phase microextraction/accelerated solvent extraction-gas chromatography-mass spectrometry]. PubMed: Organosulfate formation in biogenic secondary organic aerosol. PubMed: Occupational contact dermatitis to a limonene-based solvent in a histopathology technician. PubMed: Effects of enantiomer and isomer permeation enhancers on transdermal delivery of ligustrazine hydrochloride. PubMed: [Effects of D-limonene and L-limonene on transdermal absorption of ligustrazine hydrochloride]. PubMed: The synthesis of L-carvone and limonene derivatives with increased antiproliferative effect and activation of ERK pathway in prostate cancer cells. PubMed: Influence of the addition of rosemary essential oil on the volatiles pattern of porcine frankfurters. PubMed: Biocatalytic production of perillyl alcohol from limonene by using a novel Mycobacterium sp. cytochrome P450 alkane hydroxylase expressed in Pseudomonas putida. PubMed: Fragrance allergy in patients with hand eczema - a clinical study. PubMed: Monoterpene effect on feeding choice by deer. PubMed: Molecular cloning, functional expression and characterization of d-limonene synthase from Agastache rugosa. PubMed: In vitro studies on penetration of terpenes from matrix-type transdermal systems through human skin. PubMed: Molecular cloning, functional expression and characterization of d-limonene synthase from Schizonepeta tenuifolia. PubMed: Induction of protein droplet (alpha 2 mu-globulin) nephropathy in male rats after short-term dosage with 1,8-cineole and l-limonene.