polyethylene glycol

alpha-hydro-omega-hydroxypoly(oxy-1,2-ethanediyl)

CAS: 25322-68-3 (C2 H4 O)mult-H2 O

Identification

Namepolyethylene glycol
CAS Number25322-68-3
FDA UNII16P9295IIL
Molecular Formula(C2 H4 O)mult-H2 O
MDL NumberMFCD00081839

Regulatory

FDA/DG SANTE Petitions, Reviews, NoticesFCN 107
JECFA Food AdditivePolyethylene Glycols
GSFA CodexPolyethylene Glycol (1521
DG SANTE Food Additivespolyethylene glycol
DG SANTE Food Contact Materialspolyethylene glycol
FDA Mainterm (SATF)25322-68-3 ; POLYETHYLENE GLYCOL (M W 200-9,500)
FDA RegulationFDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION

Physical Properties

Appearance colorless to white clear viscous liquid to waxy solid (est)
Food Chemicals Codex Listed No
Boiling Point 211.00 to 212.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure 0.042000 mmHg @ 25.00 °C. (est)
Flash Point 227.00 °F. TCC ( 108.20 °C. ) (est)
logP (o/w) -1.362 (est)
Soluble in water, 1e+006 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityoral-rat LD50 51310 mg/kg
Dermal Toxicityskin-rabbit LD50 > 20000 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements', 'KIDNEY, URETER, AND BLADDER: HEMATURIA\nVASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION\nCARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION)']

Safety in Use

Categorymultipurpose additives
Recommendation for polyethylene glycol usage levels up tonot for fragrance use.
Recommendation for polyethylene glycol flavor usage levels up tonot for flavor use.

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Potential Uses

binding agents emulsion stabilisers humectants solvents viscosity controlling agents

Natural Occurrence

not found in nature

Synonyms

alpha- hydro-omega-hydroxypoly(oxy-1,2-ethanediyl) polyethylene glycol 1000 NF polyethylene glycol 200 polyethylene glycol 300 polyethylene glycol 400 USP/NF/FCC polyethylene glycol 600 polyethylene glycol 8000 flakes NF polyethyleneglycol Info: EVALUATION OF CERTAIN FOOD ADDITIVES AND CONTAMINANTS US Patents: 3,953,378 - Mineral carrier for volatile substances and process for preparing same PubMed: [Effect of Triton X-100 on genetic segregation and associated monocotyledonous and dicotyledonous traits in sugarbeet (Beta vulgaris L.)]. J-Stage: Effects of Polyethylene Glycol on Bovine Intestine Alkaline Phosphatase Activity and Stability PubMed: Pharmaceutical optimization of lipid-based dosage forms for the improvement of taste-masking, chemical stability and solubilizing capacity of phenobarbital. PubMed: Room temperature ionic liquids: new GC stationary phases with a novel selectivity for flavor and fragrance analyses. PubMed: [Comparative study of the use of sennoside A and B vs polyethylene glycol and electrolytes in anterograde preparation of the colon]. PubMed: beta-D(+) glucose-glucose oxidase-catalase for use as an antioxidant system. PubMed: Palatability of colonic lavage solution is improved by the addition of artificially sweetened flavored drink mixes.