potassium bromate
bromic acid, potassium salt (1:1)
Identification
| Name | potassium bromate |
| CAS Number | 7758-01-2 |
| EINECS | 231-829-8 |
| FDA UNII | 04MB35W6ZA |
| Molecular Formula | Br K O3 |
| Molecular Weight | 166.99990000 |
| MDL Number | MFCD00011359 |
| Nikkaji Number | J43.934G |
Regulatory
| FDA Mainterm (SATF) | 7758-01-2 ; POTASSIUM BROMATE |
| FDA Regulation | FDA PART 136 -- BAKERY PRODUCTS |
Physical Properties
| Food Chemicals Codex Listed | No |
| Soluble in | water, 1e+006 mg/L @ 25 °C (est) |
Cosmetic Information
| CosIng | cosmetic data |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | oral-rat LD50 157 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements', 'LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION\nGASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"\nBEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)']
Safety in Use
| Category | malting of barley |
| Recommendation for potassium bromate usage levels up to | not for fragrance use. |
| Recommendation for potassium bromate flavor usage levels up to | not for flavor use. |
American International Chemical, Inc.
Consistent sources
North American supplier for globally sourced ingredients.
Glentham Life Sciences Ltd
The Chemical, Biochemical & Research Essentials Supplier
Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK.
Penta International Corporation
Chemistry innovation
At Penta, our products and services help businesses do business better.
Potential Uses
Natural Occurrence
Synonyms
bromate-21
bromate-50
bromate, potassium
bromic acid potassium salt (1:1)
bromic acid, potassium salt
bromic acid, potassium salt (1:1)
potassium bromate powder FCC
PubMed:
Protective effect of taurine against potassium bromate-induced hemoglobin oxidation, oxidative stress, and impairment of antioxidant defense system in blood.
PubMed:
Evaluation of repeated dose micronucleus assays of the liver and gastrointestinal tract using potassium bromate: A report of the collaborative study by CSGMT/JEMS.MMS.
PubMed:
The catalytic kinetic method for the determination of trace formaldehyde (FA) base on a bromate-eosin Y system.
PubMed:
A sensitive colorimetric method for the determination of nitrite in water supplies, meat and dairy products using ionic liquid-modified methyl red as a colour reagent.
PubMed:
A new catalytic oxidation method for sensitive quantification of bromate in flours and bottled water using AgNPs.
PubMed:
Taurine ameliorates potassium bromate-induced kidney damage in rats.
PubMed:
DNA damage and DNA-protein cross-linking induced in rat intestine by the water disinfection by-product potassium bromate.
PubMed:
Oral administration of a nephrotoxic dose of potassium bromate, a food additive, alters renal redox and metabolic status and inhibits brush border membrane enzymes in rats.
PubMed:
Oxidative stress induced by potassium bromate exposure results in altered tight junction protein expression in renal proximal tubule cells.
PubMed:
Oral administration of potassium bromate, a major water disinfection by-product, induces oxidative stress and impairs the antioxidant power of rat blood.
PubMed:
Supplementation of Nigella sativa fixed and essential oil mediates potassium bromate induced oxidative stress and multiple organ toxicity.
PubMed:
Determination of acrylamide in starch-based foods by HPLC with pre-column ultraviolet derivatization.
PubMed:
Potassium bromate causes cell lysis and induces oxidative stress in human erythrocytes.
PubMed:
[Quantification of acrylamide in foods by gas chromatography-mass spectrometry coupled with pro-column derivatization].
PubMed:
Possible involvement of oxidative stress in potassium bromate-induced genotoxicity in human HepG2 cells.
PubMed:
Impact of potassium bromate and potassium iodate in a pound cake system.
PubMed:
The effect of potassium bromate on some haematological parameters of Wistar rats.
PubMed:
Flow injection kinetic spectrophotometric method for the determination of trace amounts of nitrite.
PubMed:
Potassium bromate content of selected bread samples in Ilorin, Central Nigeria and its effect on some enzymes of rat liver and kidney.
PubMed:
Early alterations in protein and gene expression in rat kidney following bromate exposure.
PubMed:
[Relationship between toxic effects of potassium bromate and endocrine glands].
PubMed:
Kinetic-spectrophotometric determination of trace amounts of vanadium.
PubMed:
A pilot study of evaluation of the antioxidative activity of resveratrol and its analogue in a 6-month feeding test in young adult mice.
PubMed:
Protective effects of bilberry (Vaccinium myrtillus L.) extract on KBrO3-induced kidney damage in mice.
PubMed:
Impact of redox agents on the extractability of gluten proteins during bread making.
PubMed:
Kinetic spectrophotometric method for rapid determination of trace formaldehyde in foods.
PubMed:
Determination of acrylamide in Chinese traditional carbohydrate-rich foods using gas chromatography with micro-electron capture detector and isotope dilution liquid chromatography combined with electrospray ionization tandem mass spectrometry.
PubMed:
Rapid determination of acrylamide contaminant in conventional fried foods by gas chromatography with electron capture detector.
PubMed:
Multiple outbreaks of gastrointestinal illness among school children associated with consumption of flour tortillas--Massachusetts, 2003-2004.
PubMed:
Kidney toxicogenomics of chronic potassium bromate exposure in f344 male rats.
PubMed:
Quantitation of dityrosine in wheat flour and dough by liquid chromatography-tandem mass spectrometry.
PubMed:
Simultaneous spectrophotometric determination of nitrite and nitrate by flow injection analysis.
PubMed:
Lack of genotoxicity of potassium iodate in the alkaline comet assay and in the cytokinesis-block micronucleus test. Comparison to potassium bromate.
PubMed:
Characterization of sulfur speciation in low molecular weight subunits of glutenin after reoxidation with potassium iodate and potassium bromate at different pH values using x-ray absorption near-edge structure (XANES) spectroscopy.
PubMed:
Determination of acrylamide in foods by GC/MS using 13C-labeled acrylamide as an internal standard.
PubMed:
Toxic bromate residues in Nigerian bread.
PubMed:
Effect of raw wheat germ addition on the physical texture and objective color of a designer food (pan bread).
PubMed:
Requirement of glutathione and cysteine in guanine-specific oxidation of DNA by carcinogenic potassium bromate.
PubMed:
The detrimental effects of potassium bromate and thioglycolate on auditory brainstem response of guinea pigs.
PubMed:
Potassium bromate.
PubMed:
Measurement of bromate in bread by liquid chromatography with post-column flow reactor detection.
PubMed:
Hydroquinone: genotoxicity and prevention of genotoxicity following ingestion.
PubMed:
Time- and dose-dependent development of potassium bromate-induced tumors in male Fischer 344 rats.
PubMed:
DNA oxidation by potassium bromate; a direct mechanism or linked to lipid peroxidation?
PubMed:
Enhancement of ethylenethiourea recoveries in food analyses by addition of cysteine hydrochloride.
PubMed:
Evaluation of certain food additives and contaminants.
PubMed:
The determination of the flour improver potassium bromate in bread by gas chromatographic and ICP-MS methods.
PubMed:
Practical applications of element-specific detection by inductively coupled plasma atomic emission spectroscopy and inductively coupled plasma mass spectrometry to ion chromatography of foods.
PubMed:
[Substitution of ascorbic acid for potassium bromide in the making of French bread].
PubMed:
A possible role for cell proliferation in potassium bromate (KBrO3) carcinogenesis.
PubMed:
Effects of antioxidants on induction of micronuclei in rat peripheral blood reticulocytes by potassium bromate.
PubMed:
Lack of renal tumour-initiating activity of a single dose of potassium bromate, a genotoxic renal carcinogen in male F344/NCr rats.
PubMed:
Generation of active oxygen species in vitro by the interaction of potassium bromate with rat kidney cell.
PubMed:
Relation of 8-hydroxydeoxyguanosine formation in rat kidney to lipid peroxidation, glutathione level and relative organ weight after a single administration of potassium bromate.
PubMed:
Toxicity and carcinogenicity of potassium bromate--a new renal carcinogen.
PubMed:
Regulation of food-related carcinogens in Japan.
PubMed:
Mutagens and carcinogens in the diet. Regulatory perspective: Japan.
PubMed:
Micronucleus tests in mice on 39 food additives and eight miscellaneous chemicals.
PubMed:
Dose-response studies on the carcinogenicity of potassium bromate in F344 rats after long-term oral administration.
PubMed:
Potassium bromate.
PubMed:
Dose-related enhancing effect of potassium bromate on renal tumorigenesis in rats initiated with N-ethyl-N-hydroxyethyl-nitrosamine.
PubMed:
Risk evaluation of tumor-inducing substances in foods.
PubMed:
Primary mutagenicity screening of food additives currently used in Japan.
PubMed:
Carcinogenicity of potassium bromate administered orally to F344 rats.
PubMed:
Enhancement by potassium bromate of renal tumorigenesis initiated by N-ethyl-N-hydroxyethylnitrosamine in F-344 rats.
PubMed:
Induction of renal cell tumors in F-344 rats by oral administration of potassium bromate, a food additive.
PubMed:
[Carcinogenicity of potassium bromate in F-344 rats].
PubMed:
New considerations on hydrogen peroxide and related substances as food additives in view of carcinogenicity.
PubMed:
Improved 4-aminoantipyrine colorimetry for detection of residual hydrogen peroxide in noodles, fish paste, dried fish, and herring roe.
PubMed:
Long-term toxicity and carcinogenicity studies of the bread improver potassium bromate 2. Studies in mice.
PubMed:
Long-term toxicity and carcinogenicity studies of the bread improver potassium bromate 1. Studies in rats.
PubMed:
The fate of potassium bromate when used as a breadmaking improver.
PubMed:
Cysteinimetry. Determination of the potassium bromate content of buffalo milk.
PubMed:
An outbreak of food-poisoning due to a flour improver, potassium bromate.
PubMed:
Chemical food poisoning by potassium bromate. Report of an outbreak.