sodium laevo-lactate

propanoic acid, 2-hydroxy-, sodium salt, (2S)- (1:1)

CAS: 867-56-1 C3 H5 Na O3 MW: 112.06021928

Identification

Namesodium laevo-lactate
IUPACsodium (2S)-2-hydroxypropanoate
CAS Number867-56-1
EINECS212-762-3
FDA UNIIP2Y1C6M9PS
Molecular FormulaC3 H5 Na O3
Molecular Weight112.06021928
MDL NumberMFCD00066576
Nikkaji NumberJ1.170C
Beilstein4567087

Regulatory

FDA/DG SANTE Petitions, Reviews, NoticesEU SANCO

Physical Properties

Appearance colorless to pale yellow clear liquid (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 227.60 °C. @ 760.00 mm Hg (est)
Vapor Pressure 0.015000 mmHg @ 25.00 °C. (est)
Flash Point 230.00 °F. TCC ( 109.90 °C. ) (est)
logP (o/w) -0.698 (est)
Soluble in water, 1e+006 mg/L @ 25 °C (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesbuffering agents

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorycosmetic and flavor agents
Recommendation for sodium laevo-lactate usage levels up tonot for fragrance use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

(S)-2- hydroxypropionic acid sodium salt L- lactic acid sodium salt propanoic acid, 2-hydroxy-, monosodium salt, (2S)- propanoic acid, 2-hydroxy-, sodium salt, (2S)- (1:1) sarcolactic acid sodium salt sodium (2S)-2-hydroxypropanoate sodium (S)-lactate sodium L-lactate sodium L(+)-lactate PubMed: Mechanistic modeling of monocarboxylate transporter-mediated toxicokinetic/toxicodynamic interactions between γ-hydroxybutyrate and L-lactate. PubMed: Spontaneous supersaturation of calcium D-gluconate during isothermal dissolution of calcium L-lactate in aqueous sodium D-gluconate. PubMed: Aqueous solubility of calcium L-lactate, calcium D-gluconate, and calcium D-lactobionate: importance of complex formation for solubility increase by hydroxycarboxylate mixtures. PubMed: Neuroprotective effects of lactate in brain ischemia: dependence on anesthetic drugs. PubMed: Sodium L-lactate differently affects brain-derived neurothrophic factor, inducible nitric oxide synthase, and heat shock protein 70 kDa production in human astrocytes and SH-SY5Y cultures. PubMed: Exogenous L-lactate clearance in adult horses. PubMed: Prevention of acute/severe hypoglycemia-induced neuron death by lactate administration. PubMed: A method for lactate and pyruvate determination in filter-paper dried blood spots. PubMed: Effectiveness of combined preservation methods to extend the shelf life of Morcilla de Burgos. PubMed: Histidine inhibits the degradation of cells suspended in Ringer's lactate. PubMed: Field-scale demonstration of induced biogeochemical reductive dechlorination at Dover Air Force Base, Dover, Delaware. PubMed: Optimization of L-lactic acid feeding for the production of poly-D-3-hydroxybutyric acid by Alcaligenes eutrophus in fed-batch culture. PubMed: Evidence for swelling-induced adenosine and adenine nucleotide release in rat cerebral cortex exposed to monocarboxylate-containing or hypotonic artificial cerebrospinal fluids. PubMed: Glycolysis prevents anoxia-induced synaptic transmission damage in rat hippocampal slices. PubMed: Effect of continuous venovenous hemofiltration with dialysis on lactate clearance in critically ill patients. PubMed: Neurocardiac toxicity of racemic D,L-lactate fluids. PubMed: Effects of sodium L-lactate and sodium racemic lactate on intraoperative acid-base status. PubMed: Plasma growth hormone and prolactin responses to graded levels of acute exercise and to a lactate infusion. PubMed: Stoichiometry of the renal sodium-L-lactate cotransporter. PubMed: Clinical evaluation of sodium bicarbonate, sodium L-lactate, and sodium acetate for the treatment of acidosis in diarrheic calves. PubMed: Lactate reverses insulin-induced hypoglycemic stupor in suckling-weanling mice: biochemical correlates in blood, liver, and brain. PubMed: Comparison of the kinetics and utilisation of D(-)-and L(+)-sodium lactate in normal man. PubMed: Utilization of L(+) lactate in patients with liver disease. PubMed: A model of L(+)-lactate metabolism in normal man. PubMed: Disturbances of lactate metabolism in patients with liver damage due to paracetamol overdose. PubMed: Facilitated diffusion of lactic acid in the guinea-pig placenta. PubMed: Preferential uptake of lactate by the normal myocardium in dogs. PubMed: Is lactate involved in phenformin-induced insulin secretion? PubMed: Evidence for a role of exogenous or endogenous hyperlactatemia in insulin secretion in the dog. PubMed: Liver function and lactate metabolism in the ill surgical patient. PubMed: Nutritional requirements of anaerobic coryneforms. PubMed: Use of endogenous triglycerides to support gluconeogenesis in the perfused isolated rat liver. PubMed: Growth hormone secretion in acid-base alterations at rest and during exercise. PubMed: Influence of lactate infusion on glucose and FFA metabolism in man. PubMed: Glucagon and insulin control of gluconeogenesis in the perfused isolated rat liver. Effects on cellular metabolite distribution. PubMed: The effect of exercise on lactate metabolism. PubMed: Pharmacologic differences between sodium D-lactate and sodium L-lactate in sheep. PubMed: Metabolic effects of infused sodium L (+) lactate in man before and after triiodothyronine treatment. PubMed: Relationship between excess respiratory metabolism and utilization of intravenously infused sodium racemic lactate and sodium L(-) lactate.