zinc orotate
zinc, bis(1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylato-N3,O4)-, (T-4)-
Identification
| Name | zinc orotate |
| IUPAC | zinc 2,4-dioxo-1H-pyrimidine-6-carboxylate |
| CAS Number | 68399-76-8 |
| EINECS | 269-988-0 |
| FDA UNII | Z722242H10 |
| Molecular Formula | C10 H6 N4 O8 Zn |
| Molecular Weight | 375.55942000 |
| MDL Number | MFCD00167357 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Flash Point | 32.00 °F. TCC ( 0.00 °C. ) (est) |
| logP (o/w) | -0.928 (est) |
| Soluble in | water, 2.114e+005 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | nutrient supplements, EFSA concludes: use is of safety concern. |
| Recommendation for zinc orotate usage levels up to | not for fragrance use. |
| Recommendation for zinc orotate flavor usage levels up to | not for flavor use. |
Penta International Corporation
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Potential Uses
Natural Occurrence
Synonyms
orotic acid zinc salt dihydrate
bis(1,2,3,6-
tetrahydro-2,6-dioxopyrimidine-4-carboxylato-N3,O4)zinc
zinc 1,2,3,6-tetrahydro-2,6-dioxopyrimidine-4-carboxylate (1:2)
zinc 2,4-dioxo-1H-pyrimidine-6-carboxylate
zinc, bis(1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylato-N3,O4)-, (T-4)-
PubMed:
Comparative in vitro toxicity of seven zinc-salts towards neuronal PC12 cells.
PubMed:
Ineffectiveness of zinc gluconate nasal spray and zinc orotate lozenges in common-cold treatment: a double-blind, placebo-controlled clinical trial.
PubMed:
The progression of aging in klotho mutant mice can be modified by dietary phosphorus and zinc.
PubMed:
Further studies on selective radioprotection by organic zinc salts and synergism of zinc aspartate with WR 2721.
PubMed:
Synergism of organic zinc salts and sulfhydryl compounds (thiols) in the protection of mice against acute ethanol toxicity, and protective effects of various metal salts.
PubMed:
Some aspects of a non-linear effect of zinc ions on the histamine release from rat peritoneal mast cells.
PubMed:
The bioavailability and pharmacokinetics of three zinc salts: zinc pantothenate, zinc sulfate and zinc orotate.