zinc oxide

zinc monoxide

CAS: 1314-13-2 O Zn MW: 81.37920000

Identification

Namezinc oxide
IUPACoxozinc
CAS Number1314-13-2
EINECS215-222-5
FDA UNIISOI2LOH54Z
Molecular FormulaO Zn
Molecular Weight81.37920000
MDL NumberMFCD00011300

Regulatory

FDA/DG SANTE Petitions, Reviews, Notices182.8991
DG SANTE Food Contact Materialszinc oxide
FDA Mainterm (SATF)1314-13-2 ; ZINC OXIDE
FDA RegulationFDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS

Physical Properties

Appearance white powder (est)
Assay 800.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 6431 mg/L @ 25 °C (est)

Cosmetic Information

CosIng['cosmetic data2', 'cosmetic data']
Cosmetic Usesbulking agents

Organoleptic Properties

Odor Strength none
Odor Description at 100.00 %.

Safety Information

European informationMost important hazard(s):
Oral/Parenteral Toxicityoral-rat LD > 8737 mg/kg
Dermal ToxicityNot determined
Inhalation Toxicityinhalation-mouse LC50 2500 mg/m3

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorycertain adjuvants and production aids
Recommendation for zinc oxide usage levels up tonot for fragrance use.
Recommendation for zinc oxide flavor usage levels up tonot for flavor use.

American International Chemical, Inc.

Consistent sources

North American supplier for globally sourced ingredients.

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BOC Sciences

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Charkit Chemical Corporation

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ECSA Chemicals

Human Chemistry

ECSA Chemicals has been active since 1913 in the trading and international commerce of raw materials. With an organisation divided into industrial segments managed by specialists, it has become one of...

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Glentham Life Sciences Ltd

The Chemical, Biochemical & Research Essentials Supplier

Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK.

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Penta International Corporation

Chemistry innovation

At Penta, our products and services help businesses do business better.

View All Website (973) 740-2300 lisaa@pentamfg.com

Symrise AG

Always Insiring More

Symrise aroma molecules & cosmetic ingredients for unique and innovative fragrances, flavors and cosmetics.

View All Website +49 5531 90 0 scentandcare@symrise.com

Potential Uses

cosmetic colorants

Natural Occurrence

not found in nature

Synonyms

c.i. 77947 C.I. pigment white 4 ci 77947 CI pigment white 4 dome paste bandage kadox 72 nogenol pigment white 4 protox 168 supertah unichem ZO vandem VAC vandem VOC vandem VPC z-cote oxo zinc zinc gelatin zinc monoxide zinc oxide (ZnO) zinc oxide microfine 65 dispersion in C12-15 alkyl benzoate zinc oxide NDM zinc oxide NDM zinc oxide and dimethicone zinc oxide neutral zinc oxide PI (Symrise) zinc oxide powder zinc oxide tech grade zinc oxide USP FCC low lead zinc oxide USP FCC powder zinc oxide USP sunscreen grade zinc white zinclear ZNO zinc oxide USP-1 ZNO zinc oxide USP-2 zoco 102 USP-standard PubMed: Characterization and stability analysis of zinc oxide nanoencapsulated conjugated linoleic acid. PubMed: Cytotoxic Evaluation of Nanostructured Zinc Oxide (ZnO) Thin Films and Leachates. PubMed: Accumulation and toxicity of CuO and ZnO nanoparticles through waterborne and dietary exposure of goldfish (Carassius auratus). PubMed: Cerium dioxide and zinc oxide nanoparticles alter the nutritional value of soil cultivated soybean plants. PubMed: Incorporation of essential oils and nanoparticles in pullulan films to control foodborne pathogens on meat and poultry products. PubMed: Zinc oxide nanoparticles induce apoptosis by enhancement of autophagy via PI3K/Akt/mTOR inhibition. PubMed: Toll-like receptor 6 mediated inflammatory and functional responses of Zinc Oxide nanoparticles primed macrophages. PubMed: Evaluation of the efficacy and safety of a marine-derived Bacillus strain for use as an in-feed probiotic for newly weaned pigs. PubMed: Effect of seaweed-derived laminarin and fucoidan and zinc oxide on gut morphology, nutrient transporters, nutrient digestibility, growth performance and selected microbial populations in weaned pigs. PubMed: Lack of genotoxic potential of ZnO nanoparticles in in vitro and in vivo tests. PubMed: Antibacterial activity and mechanism of Ag-ZnO nanocomposite on S. aureus and GFP-expressing antibiotic resistant E. coli. PubMed: Additive effect of zinc oxide nanoparticles and isoorientin on apoptosis in human hepatoma cell line. PubMed: Mechanism of uptake of ZnO nanoparticles and inflammatory responses in macrophages require PI3K mediated MAPKs signaling. PubMed: Metalloproteins and phytochelatin synthase may confer protection against zinc oxide nanoparticle induced toxicity in Caenorhabditis elegans. PubMed: Zinc oxide nanoparticles delay soybean development: a standard soil microcosm study. PubMed: Progress in the characterization and safety evaluation of engineered inorganic nanomaterials in food. PubMed: Dermal absorption and short-term biological impact in hairless mice from sunscreens containing zinc oxide nano- or larger particles. PubMed: Zinc absorption by young adults from supplemental zinc citrate is comparable with that from zinc gluconate and higher than from zinc oxide. PubMed: Photoprotection: part II. Sunscreen: development, efficacy, and controversies. PubMed: Zinc oxide nanoparticles provide an adjuvant effect to ovalbumin via a Th2 response in Balb/c mice. PubMed: ZnO nanofertilizer and He Ne laser irradiation for promoting growth and yield of sweet basil plant. PubMed: Fate of ZnO nanoparticles in soils and cowpea (Vigna unguiculata). PubMed: Surface coatings of ZnO nanoparticles mitigate differentially a host of transcriptional, protein and signalling responses in primary human olfactory cells. PubMed: Effect of the interaction of seaweed extracts containing laminarin and fucoidan with zinc oxide on the growth performance, digestibility and faecal characteristics of growing piglets. PubMed: Antibacterial and antifungal activity of photoactivated ZnO nanoparticles in suspension. PubMed: Minimal intestinal epithelial cell toxicity in response to short- and long-term food-relevant inorganic nanoparticle exposure. PubMed: Potential treatments to reduce phorbol esters levels in jatropha seed cake for improving the value added product. PubMed: Nanosized zinc oxide induces toxicity in human lung cells. PubMed: Modulation of the pharmacokinetics of zinc oxide nanoparticles and their fates in vivo. PubMed: Effect of zinc oxide nanoparticles on the function of MC3T3-E1 osteoblastic cells. PubMed: Cytotoxicity of cultured macrophages exposed to antimicrobial zinc oxide (ZnO) coatings on nanoporous aluminum oxide membranes. PubMed: Inhibitory effect of high-dosage zinc oxide dietary supplementation on Campylobacter coli excretion in weaned piglets. PubMed: Preparation and characterization of bionanocomposite films filled with nanorod-rich zinc oxide. PubMed: Physical-mechanical and antimicrobial properties of nanocomposite films with pediocin and ZnO nanoparticles. PubMed: Chronic arsenicosis in cattle: possible mitigation with Zn and Se. PubMed: UVA radiation induced ultrafast electron transfer from a food carcinogen benzo[a]pyrene to organic molecules, biological macromolecules, and inorganic nano structures. PubMed: [Research progress on biological toxicity of zinc oxide nanoparticle and its mechanism]. PubMed: Bioavailability of zinc oxide added to corn tortilla is similar to that of zinc sulfate and is not affected by simultaneous addition of iron. PubMed: Rat pancreatitis produced by 13-week administration of zinc oxide nanoparticles: biopersistence of nanoparticles and possible solutions. PubMed: Fast classification of meat spoilage markers using nanostructured ZnO thin films and unsupervised feature learning. PubMed: Enzyme-mimetic effects of gold@platinum nanorods on the antioxidant activity of ascorbic acid. PubMed: In situ synchrotron X-ray fluorescence mapping and speciation of CeO₂ and ZnO nanoparticles in soil cultivated soybean (Glycine max). PubMed: Molecular cloning, characterization of CAT, and eco-toxicological effects of dietary zinc oxide on antioxidant enzymes in Eisenia fetida. PubMed: In vivo nanotoxicity assays in plant models. PubMed: Soybean susceptibility to manufactured nanomaterials with evidence for food quality and soil fertility interruption. PubMed: Assessment of phytotoxicity of ZnO NPs on a medicinal plant, Fagopyrum esculentum. PubMed: Pharmacokinetics, tissue distribution, and excretion of zinc oxide nanoparticles. PubMed: Development and evaluation of ZnO-Fe2O3 based nanocomposite sensors for butanol detection. PubMed: Nanoscale ZnO induces cytotoxicity and DNA damage in human cell lines and rat primary neuronal cells. PubMed: Examination of nanoparticle inactivation of Campylobacter jejuni biofilms using infrared and Raman spectroscopies. PubMed: Effects of dietary spray-dried egg on growth performance and health of weaned pigs. PubMed: Morphology and antifungal effect of nano-ZnO and nano-Pd-doped nano-ZnO against Aspergillus and Candida. PubMed: Dissolution kinetics of macronutrient fertilizers coated with manufactured zinc oxide nanoparticles. PubMed: Influence of simulated gastrointestinal conditions on particle-induced cytotoxicity and interleukin-8 regulation in differentiated and undifferentiated Caco-2 cells. PubMed: ZnO nanorod coating for solid phase microextraction and its applications for the analysis of aldehydes in instant noodle samples. PubMed: Induction of oxidative stress, DNA damage and apoptosis in mouse liver after sub-acute oral exposure to zinc oxide nanoparticles. PubMed: The influence of operational parameters and feed preparation in a convective batch ribbon powder mixer. PubMed: ZnO nanorod array polydimethylsiloxane composite solid phase micro-extraction fiber coating: fabrication and extraction capability. PubMed: Tracing the pathogen Staphylococcus aureus on laboratory ants using physical preconcentration coupled ZnO nanoparticle assisted MALDI-TOF MS. PubMed: Preparation, characterization and antibacterial applications of ZnO-nanoparticles coated polyethylene films for food packaging. PubMed: Gold coated zinc oxide nanonecklaces as a SERS substrate. PubMed: Effect of Helicobacter pylori infection on iron absorption in asymptomatic adults consuming wheat flour fortified with iron and zinc. PubMed: Distinct biological effects of different nanoparticles commonly used in cosmetics and medicine coatings. PubMed: Designing and surface modification of zinc oxide nanoparticles for biomedical applications. PubMed: Acceptability of complementary foods and breads prepared from zinc-fortified cereal flours among young children and adults in Senegal. PubMed: Effect of zinc and iron fortification of the feed on liver and thyroid function in rats. PubMed: Comparative chronic toxicity of nanoparticulate and ionic zinc to the earthworm Eisenia veneta in a soil matrix. PubMed: Immobilization of Aspergillus oryzae β galactosidase on zinc oxide nanoparticles via simple adsorption mechanism. PubMed: A novel approach reveals that zinc oxide nanoparticles are bioavailable and toxic after dietary exposures. PubMed: ZnO-ZnS QDs interfacial heterostructure for drug and food delivery application: enhancement of the binding affinities of flavonoid aglycones to bovine serum albumin. PubMed: Antibacterial and physical properties of poly(vinyl chloride)-based film coated with ZnO nanoparticles. PubMed: Antibacterial activity and mechanism of action of zinc oxide nanoparticles against Campylobacter jejuni. PubMed: Effect of mineral fortification on plasma biochemical profile in rats. PubMed: Formation of polychlorinated dibenzo-p-dioxins/dibenzofurans (PCDD/Fs) from a refinery process for zinc oxide used in feed additives: a source of dioxin contamination in Chilean pork. PubMed: Inactivation of Salmonella in liquid egg albumen by antimicrobial bottle coatings infused with allyl isothiocyanate, nisin and zinc oxide nanoparticles. PubMed: Titanium dioxide and zinc oxide nanoparticles in sunscreens: focus on their safety and effectiveness. PubMed: Investigation of ZnO nanoparticles' ecotoxicological effects towards different soil organisms. PubMed: Particles which may occur in food or food packaging can exert cytotoxicity and (oxidative) DNA damage in target cells of the human intestine. PubMed: A preemptive strike on the FDA approval of the Sargenti paste. PubMed: Metabonomic study on women of reproductive age treated with nutritional intervention: screening potential biomarkers related to neural tube defects occurrence. PubMed: Characterization and stability analysis of zinc oxide nanoencapsulated conjugated linoleic acid. PubMed: Does the newly weaned piglet select a zinc oxide supplemented feed, when given the choice? PubMed: Magnetic-field-assisted rapid ultrasensitive immunoassays using Fe3O4/ZnO/Au nanorices as Raman probes. PubMed: Antifungal activity of zinc oxide nanoparticles against Botrytis cinerea and Penicillium expansum. PubMed: A highly sensitive H2O2 sensor based on zinc oxide nanorod arrays film sensing interface. PubMed: Effect of ultrafine zinc oxide (ZnO) nanoparticles on induction of oral tolerance in mice. PubMed: Nanoparticles: a closer look at their dermal effects. PubMed: Toxicity of zinc oxide (ZnO) nanoparticles on human bronchial epithelial cells (BEAS-2B) is accentuated by oxidative stress. PubMed: Comparative cytotoxicity of Al2O3, CeO2, TiO2 and ZnO nanoparticles to human lung cells. PubMed: Finger millet (Eleucine coracana) flour as a vehicle for fortification with zinc. PubMed: Assay-dependent phytotoxicity of nanoparticles to plants. PubMed: Development and optimization of iron- and zinc-containing nanostructured powders for nutritional applications. PubMed: ZnO nanorod array solid phase micro-extraction fiber coating: fabrication and extraction capability. PubMed: Antibacterial activities of zinc oxide nanoparticles against Escherichia coli O157:H7. PubMed: Antimicrobial efficacy of zinc oxide quantum dots against Listeria monocytogenes, Salmonella Enteritidis, and Escherichia coli O157:H7. PubMed: Herpes labialis. PubMed: Toxicity of nanoparticulate and bulk ZnO, Al2O3 and TiO2 to the nematode Caenorhabditis elegans. PubMed: Stability analysis of zinc oxide-nanoencapsulated conjugated linoleic acid and gamma-linolenic acid. PubMed: Dietary supplementation with zinc oxide stimulates ghrelin secretion from the stomach of young pigs. PubMed: Transfer of dietary zinc and fat to milk--evaluation of milk fat quality, milk fat precursors, and mastitis indicators. PubMed: Zinc bioavailability from zinc-fortified foods. PubMed: Mexoryl: a review of an ultraviolet a filter. PubMed: Dynamics of innate immune response in Gallus domesticus using two methods of induced molting. PubMed: Fortifying milk with ferrous gluconate and zinc oxide in a public nutrition program reduced the prevalence of anemia in toddlers. PubMed: Herpes labialis. PubMed: Suspected zinc-induced copper deficiency in growing kittens exposed to galvanised iron. PubMed: Effect of prior sporidesmin intoxication on the pancreopathy associated with zinc oxide toxicity. PubMed: Zinc absorption from zinc oxide, zinc sulfate, zinc oxide + EDTA, or sodium-zinc EDTA does not differ when added as fortificants to maize tortillas. PubMed: Na2EDTA enhances the absorption of iron and zinc from fortified rice flour in Sri Lankan children. PubMed: Effects of copper and zinc source on performance and humoral immune response of newly received, lightweight beef heifers. PubMed: Large doses of zinc oxide increases the activity of hydrolases in rats. PubMed: Quantitative evaluation of antifungal activity of metallic oxide powders (MgO, CaO and ZnO) by an indirect conductimetric assay. PubMed: Proposed nutrient composition for fortified complementary foods. PubMed: Zinc and copper: proposed fortification levels and recommended zinc compounds. PubMed: Absorption of zinc from wheat products fortified with iron and either zinc sulfate or zinc oxide. PubMed: Exchangeable zinc pool size in infants is related to key variables of zinc homeostasis. PubMed: Toxic metals and metalloids in dietetic products. PubMed: Cofortification of iron-fortified flour with zinc sulfate, but not zinc oxide, decreases iron absorption in Indonesian children. PubMed: The effect of five-year zinc supplementation on serum zinc, serum cholesterol and hematocrit in persons randomly assigned to treatment group in the age-related eye disease study: AREDS Report No. 7. PubMed: Investigation of excretion and absorption of different zinc salts in puppies. PubMed: The effect of zinc oxide supplementation on the stability of the intestinal flora with special reference to composition of coliforms in weaned pigs. PubMed: Bioavailability of zinc in several sources of zinc oxide, zinc sulfate, and zinc metal. PubMed: [Addition of vitamins and minerals to corn and wheat flour in Mexico]. PubMed: Microfine zinc oxide (Z-cote) as a photostable UVA/UVB sunblock agent. PubMed: Iron and zinc interactions in humans. PubMed: Dietary zinc oxide in weaned pigs--effects on performance, tissue concentrations, morphology, neutrophil functions and faecal microflora. PubMed: Determination of total phosphorus in foods by colorimetry: summary of NMKL collaborative study. PubMed: Zinc source influences zinc retention in hair and hair growth in the dog. PubMed: Absorption and retention of zinc when administered as an amino-acid chelate in the dog. PubMed: Determination of total phosphorus in foods by colorimetric measurement of phosphorus as molybdenum blue after dry-ashing: NMKL interlaboratory study. PubMed: Bioavailability of zinc from inorganic and organic sources for pigs fed corn-soybean meal diets. PubMed: Sargenti defended. PubMed: Growth and plasma zinc responses of young pigs fed pharmacologic levels of zinc. PubMed: FDA explains status of N2 material. PubMed: Methodology for assessing zinc bioavailability: efficacy estimates for zinc-methionine, zinc sulfate, and zinc oxide. PubMed: Interspecies variations in response to topical application of selected zinc compounds. PubMed: [Extra zinc oxide in swine fodder... Why not!]. PubMed: Zinc methionine for ruminants: relative bioavailability of zinc in lambs and effects of growth and performance of growing heifers. PubMed: Experimental systems which modify and simulate rapeseed-induced liver haemorrhages in in-lay hens. PubMed: Withdrawal of zinc oxide-containing diets from mature, female domestic fowl: effects on selected tissue mineral contents. PubMed: Withdrawal of zinc oxide-containing diets from mature, female domestic fowl: effects on laying performance and the weights of selected tissues. PubMed: Comparison of the effects of feeding diets supplemented with zinc oxide or zinc acetate on the performance and tissue mineral content of mature female fowls. PubMed: [Hygienic evaluation of the zinc ion content in extracts from rubbers in contact with food products]. PubMed: Effects of short- and long-term feeding of zinc oxide-supplemented diets on the mature, female domestic fowl with special reference to tissue mineral content. PubMed: Zinc toxicity in the fowl: ultrastructural pathology and relationship to selenium, lead and copper. PubMed: Respiratory disease in adult cattle. PubMed: Comparison of dietary hydrated copper sulphate, dietary zinc oxide and a direct method for inducing a moult in laying hens. PubMed: N2: clarifying the controversy. PubMed: The effects of high dietary zinc on food intake in the domestic fowl. PubMed: Antibacterial properties of periodontal dressings. PubMed: Sensitizing properties of food additives and other commercial products.