pimpinellin
2H-furo[2,3-h]-1-benzopyran-2-one, 5,6-dimethoxy-
Identification
| Name | pimpinellin |
| IUPAC | 5,6-dimethoxyfuro[2,3-h]chromen-2-one |
| CAS Number | 131-12-4 |
| FDA UNII | D419UK1B4L |
| Molecular Formula | C13 H10 O5 |
| Molecular Weight | 246.21870000 |
| Nikkaji Number | J5.558A |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 117.00 to 119.00 °C. @ 760.00 mm Hg |
| Boiling Point | 441.00 to 442.00 °C. @ 760.00 mm Hg (est) |
| Flash Point | 429.00 °F. TCC ( 220.50 °C. ) (est) |
| logP (o/w) | 1.477 (est) |
| Soluble in | alcohol |
| Insoluble in | water |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for pimpinellin usage levels up to | not for fragrance use. |
| Recommendation for pimpinellin flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
5,6-
dimethoxy-2H-furo(2,3-h)-1-benzopyran-2-one
5,6-
dimethoxy-2H-furo[2,3-h]-1-benzopyran-2-one
5,6-
dimethoxy-2H-furo[2,3-h]chromen-2-one
5,6-
dimethoxyfurano-4,5,7,8-coumarin
5,6-
dimethoxyfuro[2,3-h]chromen-2-one
2H-
furo(2,3-h)-1-benzopyran-2-one, 5,6-dimethoxy-
2H-
furo[2,3-h]-1-benzopyran-2-one, 5,6-dimethoxy-
4-
hydroxy-6,7-dimethoxy-5-benzofuranacrylic acid d-lactone
PubMed:
Simultaneous determination of 12 coumarins in bamboo leaves by HPLC.
PubMed:
Total syntheses of the coumarin-containing natural products pimpinellin and fraxetin using Au(I)-catalyzed intramolecular hydroarylation (IMHA) chemistry.
PubMed:
The Canadian medicinal plant Heracleum maximum contains antimycobacterial diynes and furanocoumarins.
PubMed:
Discovery and antitumor activities of constituents from Cyrtomium fortumei (J.) Smith rhizomes.
PubMed:
Determination of cnidilin and its two metabolites in rat plasma by high-performance liquid chromatography-electrospray ionization tandem mass spectrometry.
PubMed:
Determination of cnidilin and its two metabolites in rat bile and stool after oral administration by HPLC/electrospray ionization tandem mass spectrometry.
PubMed:
Separation and purification of furanocoumarins from Toddalia asiatica (L.) Lam. using microwave-assisted extraction coupled with high-speed counter-current chromatography.
PubMed:
Simultaneous determination of pimpinellin, isopimpinellin and phellopterin in rat plasma by a validated UPLC-MS/MS and its application to a pharmacokinetic study after administration of Toddalia asiatica extract.
PubMed:
Changes in the phenolic and lipophilic composition, in the enzyme inhibition and antiproliferative activity of Ficus carica L. cultivar Dottato fruits during maturation.
PubMed:
Simultaneous quantification of 17 constituents from Yuanhu Zhitong tablet using rapid resolution liquid chromatography coupled with a triple quadrupole electrospray tandem mass spectrometry.
PubMed:
Quantitative analysis of nine coumarins in rat urine and bile after oral administration of Radix Glehniae extract by high-performance liquid chromatography-electrospray ionization tandem mass spectrometry.
PubMed:
Simultaneous and sensitive determination of xanthotoxin, psoralen, isoimpinellin and bergapten in rat plasma by liquid chromatography-electrospray ionization mass spectrometry.
PubMed:
Phytophotodermatitis in Rijeka region, Croatia.
PubMed:
Supercritical fluid extraction for identification and determination of volatile metabolites from Angelica dahurica by GC-MS.
PubMed:
A pimpinellin monomer and dimer isolated from the roots of Esenbeckia grandiflora.
PubMed:
Computer-assisted, high-performance liquid chromatography with mass spectrometric detection for the analysis of coumarins in Peucedanum palustre and Angelica archangelica.
PubMed:
The furanocoumarins in the roots of Heracleum sibiricum L.
PubMed:
Inducible nitric oxide synthase inhibitors of Chinese herbs. Part 2: naturally occurring furanocoumarins.
PubMed:
Rapid determination of furanocoumarins in creams and pomades using SPE and GC.
PubMed:
Isolation And Structure Elucidation Of 5,7-disubstituted Simple Coumarins In The Fruits Of Heracleum Mantegazzianum.
PubMed:
Identification of eight coumarins occurring with psoralen, xanthotoxin, and bergapten on leaf surfaces.
PubMed:
Heracleum mantegazzianum growth phases and furocoumarin content.
PubMed:
Identification of psoralen, 8-methoxypsoralen, isopimpinellin, and 5,7-dimethoxycoumarin in Pelea anisata H. Mann.
PubMed:
Phototoxicity from furocoumarins (psoralens) of Heracleum laciniatum in a patient with vitiligo. Action spectrum studies on bergapten, pimpinellin, angelicin and sphondin.
PubMed:
Furocoumarins of Heracleum laciniatum: isolation, phototoxicity, absorption and action spectra studies.
PubMed:
Accidental induction of photocontact allergy to Heracleum laciniatum.