2,6-dimethyl pyrazine

2,6-dimethylpyrazine

CAS: 108-50-9 C6 H8 N2 MW: 108.14376000 chocolate meaty

Identification

Name2,6-dimethyl pyrazine
IUPAC2,6-dimethylpyrazine
CAS Number108-50-9
EINECS203-589-4
FDA UNIIN77Q72C9I3
Molecular FormulaC6 H8 N2
Molecular Weight108.14376000
MDL NumberMFCD00006148
Nikkaji NumberJ1.498B
Beilstein0107052
CoE Number2211
XlogP30.50 (est)

Regulatory

JECFA Food Flavoring767 2,6-dimethylpyrazine
DG SANTE Food Flavourings14.021 2,6-dimethylpyrazine
FEMA Number3273
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)108-50-9 ; 2,6-DIMETHYLPYRAZINE

Physical Properties

Appearance white to yellow crystals (est)
Assay 98.00 to 100.00
Additional Assay Information sum of 2,3- 2,5- and 2,6- isomers
Food Chemicals Codex Listed Yes
Melting Point 37.00 to 48.00 °C. @ 760.00 mm Hg
Boiling Point 154.00 to 155.00 °C. @ 760.00 mm Hg
Vapor Pressure 3.873000 mmHg @ 25.00 °C. (est)
Flash Point 127.00 °F. TCC ( 52.78 °C. )
logP (o/w) 0.540
Soluble in alcohol
Insoluble in water

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesperfuming agents

Organoleptic Properties

Odor Strength medium ,
Substantivity 37
Odor Description
at 10.00 % in dipropylene glycol.
Chocolate, Nutty, Roasted
ROAST BEEF, COCOA, COFFEE, NUTTY
Roast, coffee, peanut and meat
Odor sample from Advanced Biotech. Inc.
Taste Description
meaty nutty roasted cocoa brothy bready coffee musty
nutty coffee cocoa musty bready meaty
nutty coffee cocoa musty bready meaty
nutty coffee cocoa musty bready meaty

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Oral/Parenteral Toxicityoral-rat LD50 880 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavor and fragrance agents
RIFM Fragrance Material Safety AssessmentSearch
Recommendation for 2,6-dimethyl pyrazine usage levels up to0.0500 % in the fragrance concentrate.
Maximised Survey-derived Daily Intakes (MSDI-EU)1.30 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA)2.00 (μg/capita/day)
Structure ClassII
baked goods10.00000
beverages(nonalcoholic)10.00000
beverages(alcoholic)0.10000
breakfast cereal10.00000
cheese-
chewing gum-
condiments / relishes10.00000
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy10.00000
fruit ices-
gelatins / puddings10.00000
granulated sugar-
gravies10.00000
hard candy10.00000
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products10.00000
milk products10.00000
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy10.00000
soups10.00000
sugar substitutes-
sweet sauces-

Advanced Biotech. Inc.

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Augustus Oils Ltd

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FRUTAROM USA INC,

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Indukern, S.A. F&F Ingredients Division

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View All Website +34 93 506 91 00 info@indukern.es

Jiangyin Healthway International Trade Co., Ltd

Independent Ingredients Supplier

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M&U International LLC

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Myrazine LLC

EU Natural Ingredients from Fermentation

All the materials are sourced from fermentation.

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Riverside Aromatics Ltd.

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Robinson Brothers Limited

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Award-winning UK chemical manufacturer of chemical intermediates and high-impact aroma chemicals.

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R C Treatt and Co Ltd

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Potential Uses

FL beef roasted beef FL bread FL chocolate cocoa FR coffee fried FR maple FL nut FR tobacco FL vegetable FL yeast

Natural Occurrence

beef roasted beef PMC beer PMC bread white bread PMC coffee roasted coffee PMC fenugreek seed garlic bulb kohlrabi stem lavender oil spike spain @ 0.310% Data potato chip PMC tea whiskey

Synonyms

2,6- dimethyl paradiazine 2,6- dimethyl piazine 2,6- dimethyl pyrazine, kosher 2,6- dimethyl-1,4-diazine dimethyl-2,6 pyrazine 2,6- dimethylparadiazine 2,6- dimethylpiazine 2,6- dimethylpyrazine 2,6 dimethylpyrazine 3,5- dimethylpyrazine 2- methyl-6-methylpyrazine PubMed: Determination of the alkylpyrazine composition of coffee using stable isotope dilution-gas chromatography-mass spectrometry (SIDA-GC-MS). J-Stage: Chemical Profiles of Methylpyrazines Contained in Commercially Available Natto PubMed: Pyrazine analogues are active components of wolf urine that induce avoidance and freezing behaviours in mice. J-Stage: Quantitative Analysis of Alkylpyrazines in Regular- and Low-fat Commercial Peanut Butter Preparations PubMed: Mechanistic elucidation of linker and ancillary ligand substitution reactions in Pt(II) dinuclear complexes. PubMed: Bis(cyanato-κN)tetra-kis-(2,6-dimethyl-pyrazine-κN(4))nickel(II). PubMed: Desalination of fish sauce by electrodialysis: effect on selected aroma compounds and amino acid compositions. PubMed: Identification of 2-ethyl-4-methyl-3-thiazoline and 2-isopropyl-4-methyl-3-thiazoline for the first time in nature by the comprehensive analysis of sesame seed oil. PubMed: Alkylpyrazines and other volatiles in cocoa liquors at pH 5 to 8, by Selected Ion Flow Tube-Mass Spectrometry (SIFT-MS). PubMed: Temporal changes of flavour and texture in cooked bologna type sausages as affected by fat and salt content. PubMed: Bioconversion of 2,6-dimethylpyridine to 6-methylpicolinic acid by Exophiala dermatitidis (Kano) de Hoog DA5501 cells grown on n-dodecane. PubMed: Coffee aroma--statistical analysis of compositional data. PubMed: Syntheses, structures, and photoluminescence of a series of silver(I) sulfonates with pyrazine derivatives. PubMed: Suppression of blood lipid concentrations by volatile Maillard reaction products. PubMed: Bis(2,6-dimethyl-pyrazine-κN)diiodidozinc(II). PubMed: Competition between photochemistry and energy transfer in UV-excited diazabenzenes. 4. UV photodissociation of 2,3-, 2,5-, and 2,6-dimethylpyrazine. PubMed: Structural study of silver(I) sulfonate complexes with pyrazine derivatives. PubMed: Effect of ripening time and rearing system on amino acid-related flavour compounds of Iberian ham. PubMed: Degradation of 2,5-dimethylpyrazine by Rhodococcus erythropolis strain DP-45 isolated from a waste gas treatment plant of a fishmeal processing company. PubMed: Characterization of aroma compounds of chinese "Wuliangye" and "Jiannanchun" liquors by aroma extract dilution analysis. PubMed: Determination of the 2H/1H and 15N/14N ratios of Alkylpyrazines from coffee beans (Coffea arabica L. and Coffea canephoravar. robusta) by isotope ratio mass spectrometry. PubMed: Aroma compounds in sweet whey powder. PubMed: Pyrazine derivatives in cigarette smoke inhibit hamster oviductal functioning. PubMed: [Chemical profiles of methylpyrazines contained in commercially available natto]. PubMed: Identification of aroma compounds in Parmigiano-Reggiano cheese by gas chromatography/olfactometry. PubMed: Effects of carnosine on volatile generation from Maillard reaction of ribose and cysteine. PubMed: Effect of urea on volatile generation from Maillard reaction of cysteine and ribose. PubMed: Chemical and sensory properties of liquid beet sugar. PubMed: Pyrazine formation from serine and threonine. PubMed: Effects of roasting on pyrazine contents and oxidative stability of red pepper seed oil prior to its extraction. PubMed: Quantitative analysis of alkylpyrazines in regular- and low-fat commercial peanut butter preparations. PubMed: Genotoxicity of 1,3-dithiane and 1,4-dithiane in the CHO/SCE assay and the Salmonella/microsomal test. PubMed: Headspace constituents of opium. PubMed: Effects of dimethylpyrazine isomers on reproductive and accessory reproductive organs in male rats.