Identification

Nameethyl palmitate
IUPACethyl hexadecanoate
CAS Number628-97-7
EINECS211-064-6
FDA UNIIIRD3M534ZM
Molecular FormulaC18 H36 O2
Molecular Weight284.48332000
MDL NumberMFCD00008996
Nikkaji NumberJ46.819C
Beilstein1782663
CoE Number634

Regulatory

JECFA Food Flavoring39 ethyl hexadecanoate
DG SANTE Food Flavourings09.193 ethyl hexadecanoate
FEMA Number2451
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)628-97-7 ; ETHYL PALMITATE

Physical Properties

Appearance white solid (est)
Assay 99.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 0.85700 @ 25.00 °C.
Refractive Index 1.44000 @ 20.00 °C.
Melting Point 24.00 to 26.00 °C. @ 760.00 mm Hg
Boiling Point 192.00 to 193.00 °C. @ 10.00 mm Hg, 303.00 °C. @ 760.00 mm Hg
Vapor Pressure 0.000070 mmHg @ 25.00 °C. (est)
Vapor Density >1 ( Air = 1 )
Flash Point 230.00 °F. TCC ( 110.00 °C. )
logP (o/w) 7.918 (est)
Shelf Life 24.00 month(s) or longer if stored properly.
Storage store in cool, dry place in tightly sealed containers, protected from heat and light.
Soluble in alcohol
Insoluble in water
Similar Items note

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesperfuming agents

Organoleptic Properties

Odor Strength low
Substantivity 108
Odor Description
at 100.00 %.
Waxy, fruity, creamy and milky with a balsamic nuance
soft, waxy
Mild, Waxy
Odor sample from Bedoukian Research, Inc.
Taste Description
waxy creamy dairy fermented buttery oily balsamic vanilla
at 30.00 ppm.
Fatty, waxy

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavor and fragrance agents
RIFM Fragrance Material Safety AssessmentSearch
Recommendation for ethyl palmitate usage levels up to15.0000 % in the fragrance concentrate.
baked goods20.00000
beverages(nonalcoholic)0.02000
beverages(alcoholic)0.30000
breakfast cereal-
cheese-
chewing gum0.10000
condiments / relishes-
confectionery froastings0.05000
egg products-
fats / oils-
fish products-
frozen dairy20.00000
fruit ices-
gelatins / puddings-
granulated sugar-
gravies-
hard candy40.00000
imitation dairy-
instant coffee / tea0.10000
jams / jellies-
meat products-
milk products-
nut products3.00000
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

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Alfrebro LLC/ Archer Daniels Midland Company

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Fleurchem, Inc.

Have A Flavorful Day

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Jiangyin Healthway International Trade Co., Ltd

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M&U International LLC

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Natural Advantage

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Connecting Innovators To the Building Blocks Of the Universe

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Potential Uses

FR butter FR cream emollients FL fish FL milk FR saffron FR vanilla waxy

Natural Occurrence

ambrette seed oil @ 0.10% Data apricot fruit brandy grape brandy PMC bread rye bread PMC chamomile sweet false chamomile plant coconut coriander fruit coriander oil coriander seed oil genet absolute @ 1.90% Data geranium rose-scented oil (pelargonium spp.) cuba @ 0.80% Data glycosmis pentaphylla (cor.) bark oil india @ 0.30% Data glycosmis pentaphylla (cor.) leaf oil india @ 6.50% Data guava fruit jambu flower oil brazil @ 0.10% Data lemon balm marjoram oil marjoram plant mastic fruit oil @ 8.35% Data mastic leaf oil @ 10.36% Data mutton PMC petitgrain mandarin oil @ 3.36% Data rice rum PMC sage red sage valerian root oil @ trace-0.6% Data vanilla whiskey bourbon whiskey wine witch hazel leaf oil @ 0.16% Data

Synonyms

ethyl cetylate ethyl hexadecanoate ethyl palmitate natural ethyl palmitate, natural ethylhexadecanoate hexadecanoic acid ethyl ester hexadecanoic acid, ethyl ester palmitic acid ethyl ester palmitic acid, ethyl ester PubMed: Quantification of fatty acid ethyl esters (FAEE) and ethyl glucuronide (EtG) in meconium for detection of alcohol abuse during pregnancy: Correlation study between both biomarkers. PubMed: Testing for ethanol markers in hair: Discrepancies after simultaneous quantification of ethyl glucuronide and fatty acid ethyl esters. PubMed: [Study on the chemical constituents of Viscum ovalifolium]. PubMed: Fatty acid ethyl esters in hair: correlation with self-reported ethanol intake in 160 subjects and influence of estroprogestin therapy. PubMed: A SPME-GC/MS Procedure for the Determination of Fatty Acid Ethyl Esters in Hair for Confirmation of Abstinence Test Results. PubMed: [Study on the constituents of essential oil of Shunaoxin dropping pills by GC-MS]. PubMed: Meconium fatty acid ethyl esters as biomarkers of late gestational ethanol exposure and indicator of ethanol-induced multi-organ injury in fetal sheep. PubMed: Fatty acid ethyl esters induce intestinal epithelial barrier dysfunction via a reactive oxygen species-dependent mechanism in a three-dimensional cell culture model. PubMed: Effects of ethanol and long-chain ethyl ester concentrations on volatile partitioning in a whisky model system. PubMed: Volatile constituents of roasted tigernut oil (Cyperus esculentus L.). PubMed: Anti-inflammatory activity of methyl palmitate and ethyl palmitate in different experimental rat models. PubMed: Effects of ethanol metabolites on exocytosis of pancreatic acinar cells in rats. PubMed: [Screening and identifying of hepatoprotective compounds in paeoniae radix rubra]. PubMed: A new method for quantifying prenatal exposure to ethanol by microwave-assisted extraction (MAE) of meconium followed by gas chromatography-mass spectrometry (GC-MS). PubMed: Saturated fatty acid and TLR signaling link β cell dysfunction and islet inflammation. PubMed: [Phylogenetic diversity characteristics of soil bacteria producing nematode-attracting volatiles and identification of their active compounds]. PubMed: Chemical composition, antimicrobial, and cytotoxicity studies on S. erianthum and S. macranthum essential oils. PubMed: Enzymatic synthesis of fatty acid ethyl esters by utilizing camellia oil soapstocks and diethyl carbonate. PubMed: De novo biosynthesis of biodiesel by Escherichia coli in optimized fed-batch cultivation. PubMed: Detection of fatty acid ethyl esters in skin surface lipids as biomarkers of ethanol consumption in alcoholics, social drinkers, light drinkers, and teetotalers using a methodology based on microwave-assisted extraction followed by solid-phase microextraction and gas chromatography-mass spectrometry. PubMed: Determination of fatty acid ethyl esters in hair by GC-MS and application in a population of cocaine users. PubMed: An improved method for rapidly quantifying fatty acid ethyl esters in meconium suitable for prenatal alcohol screening. PubMed: Quantitation of fatty acid ethyl esters in human meconium by an improved liquid chromatography/tandem mass spectrometry. PubMed: Determination of eight fatty acid ethyl esters in meconium samples by headspace solid-phase microextraction and gas chromatography-mass spectrometry. PubMed: Domain growth, pattern formation, and morphology transitions in Langmuir monolayers. A new growth instability. PubMed: Quantification of fatty acid ethyl esters (FAEE) and ethyl glucuronide (EtG) in meconium from newborns for detection of alcohol abuse in a maternal health evaluation study. PubMed: Chemical composition of French mimosa absolute oil. PubMed: Fatty acid ethyl ester concentrations in hair and self-reported alcohol consumption in 644 cases from different origin. PubMed: In vitro study of antibacterial activity on multi-resistant bacteria and chemical composition of the chloroform extract of endemic Centaurea drabifolia subsp. cappadocica. PubMed: Enrichment of amaranth oil with ethyl palmitate at the sn-2 position by chemical and enzymatic synthesis. PubMed: Liquid chromatography-tandem mass spectrometry for fatty acid ethyl esters in meconium: assessment of prenatal exposure to alcohol in two European cohorts. PubMed: [Immobilized lipase catalyzed synthesis of vitamin A plamitate]. PubMed: Fatty acid ethyl esters in meconium are associated with poorer neurodevelopmental outcomes to two years of age. PubMed: Determination of fatty acid ethyl esters (FAEE) and ethyl glucuronide (EtG) in hair: a promising way for retrospective detection of alcohol abuse during pregnancy? PubMed: Prevalence of fetal ethanol exposure in a regional population-based sample by meconium analysis of fatty acid ethyl esters. PubMed: Ethanol contamination leads to Fatty acid ethyl esters in hair samples. PubMed: [Extraction and identification of volatile constituents in the flowers of Aglaia odorata Lour]. PubMed: Lipase-catalyzed regioselective synthesis of steryl (6'-O-acyl)glucosides. PubMed: Controlling for serum albumin level improves the correlation between serum fatty acid ethyl esters and blood ethanol level. PubMed: Microdiesel: Escherichia coli engineered for fuel production. PubMed: Cyclic fatty acid monomer formation in domestic frying of frozen foods in sunflower oil and high oleic acid sunflower oil without oil replenishment. PubMed: Pattern formation and morphology evolution in Langmuir monolayers. PubMed: Rapid, accurate, and sensitive fatty acid ethyl ester determination by gas chromatography-mass spectrometry. PubMed: [Evaluation of the effects of glycosylation on in vivo survival of cold-storage human platelets by using rabbit model]. PubMed: Fatty acid ethyl esters, nonoxidative ethanol metabolites, synthesis, uptake, and hydrolysis by human platelets. PubMed: Fatty acid ethyl esters: markers of alcohol abuse and alcoholism. PubMed: Photodecomposition of retinyl palmitate in ethanol by UVA light-formation of photodecomposition products, reactive oxygen species, and lipid peroxides. PubMed: Unusual pheromone chemistry in the navel orangeworm: novel sex attractants and a behavioral antagonist. PubMed: Induction of apoptosis by fatty acid ethyl esters in HepG2 cells. PubMed: Comparison of ethyl glucuronide and fatty acid ethyl ester concentrations in hair of alcoholics, social drinkers and teetotallers. PubMed: Squalene in hair--a natural reference substance for the improved interpretation of fatty acid ethyl ester concentrations with respect to alcohol misuse. PubMed: Wipe-test and patch-test for alcohol misuse based on the concentration ratio of fatty acid ethyl esters and squalene CFAEE/CSQ in skin surface lipids. PubMed: Analysis of insecticidal Azadirachta indica A. Juss. fractions. PubMed: A covalently linked recombinant albumin dimer is more rapidly cleared in vivo than are wild-type and mutant C34A albumin. PubMed: Concentration of fatty acid ethyl esters in hair of alcoholics: comparison to other biological state markers and self reported-ethanol intake. PubMed: Stearic acid stimulates FA ethyl ester synthesis in HepG2 cells exposed to ethanol. PubMed: Electrophysiological responses of female and male Hypsipyla grandella (Zeller) to Swietenia macrophylla essential oils. PubMed: Fatty Acid ethyl esters in scalp, pubic, axillary, beard and body hair as markers for alcohol misuse. PubMed: Effect of hair care and hair cosmetics on the concentrations of fatty acid ethyl esters in hair as markers of chronically elevated alcohol consumption. PubMed: Neonatal hair analysis as a biomarker for in utero alcohol exposure. PubMed: A rabbit model for monitoring in vivo viability of human platelet concentrates using flow cytometry. PubMed: Negative effective surface viscosities in insoluble fatty acid monolayers: effect of phase transitions on dilational viscoelasticity. PubMed: Assessment of omega-fatty-acid-supplemented human platelets for potential improvement in long-term storage. PubMed: Fatty acid ethyl esters in hair as markers of alcohol consumption. Segmental hair analysis of alcoholics, social drinkers, and teetotalers. PubMed: Identification of chemical components of corn kernel pericarp wax associated with resistance to Aspergillus flavus infection and aflatoxin production. PubMed: Analysis of fatty acid ethyl esters in hair as possible markers of chronically elevated alcohol consumption by headspace solid-phase microextraction (HS-SPME) and gas chromatography-mass spectrometry (GC-MS). PubMed: Interactions and reactions of monolayers and Langmuir-Blodgett multilayers with compounds in the bulk phase. PubMed: Differences in the fatty acid composition of fatty acid ethyl esters in organs and their secretions. PubMed: A kinetic study of the synthesis of ascorbate fatty acid esters catalysed by immobilized lipase in organic media. PubMed: New phenylethanoids from Buddleja cordata subsp. cordata. PubMed: Independent synthesis of aminophospholipid-linked maillard products. PubMed: Are there possibilities for the detection of chronically elevated alcohol consumption by hair analysis? A report about the state of investigation. PubMed: Reduction of blood loss by infusion of human platelets in a rabbit kidney injury model. PubMed: Role of macrophages in experimental malaria: V--Effect of ethyl palmitate on macrophages in Plasmodium berghei infected mice. PubMed: Formation of fatty acid ethyl esters in rat liver microsomes. Evidence for a key role for acyl-CoA: ethanol O-acyltransferase. PubMed: Survival of fresh human platelets in a rabbit model as traced by flow cytometry. PubMed: [Preventive effects of eicosapentaenoic acid (EPA) on cholesterol gallstone formation in hamsters]. PubMed: The drinker's pancreas: molecular mechanisms emerge. PubMed: Pancreatic injury in rats induced by fatty acid ethyl ester, a nonoxidative metabolite of alcohol. PubMed: The distribution of fatty acid ethyl esters among lipoproteins and albumin in human serum. PubMed: Ethyl palmitate and ethyl oleate are the predominant fatty acid ethyl esters in the blood after ethanol ingestion and their synthesis is differentially influenced by the extracellular concentrations of their corresponding fatty acids. PubMed: Oviposition response ofLobesia botrana females to long-chain free fatty acids and esters from its eggs. PubMed: Low-density lipoprotein reconstituted with fatty acid ethyl esters as a physiological vehicle for ethyl ester delivery to intact cells. PubMed: Interaction of alpha-tocopherol with copper and its effect on lipid peroxidation. PubMed: Utilization of high-performance liquid chromatography as an enrichment step for the determination of cyclic fatty acid monomers in heated fats and biological samples. PubMed: Assessment of the hemostatic effectiveness of human platelets treated with aminomethyltrimethyl psoralen and UV A light using a rabbit ear bleeding time technique. PubMed: Semiochemical basis of infestation of honey bee brood byVarroa jacobsoni. PubMed: Mandibular gland secretions of the male beewolvesPhilanthus crabroniformis, P. barbatus, andP. pulcher (Hymenoptera: Sphecidae). PubMed: The metabolism of ethyl esters of fatty acids in adipose tissue of rats chronically exposed to ethanol. PubMed: Ethanol-induced fatty acid ethyl ester formation in vivo and in vitro in rat lung. PubMed: [GC-MS analysis of essential oil from flowers of Lonicera japonica Thunb]. PubMed: Stimulation of phagocytic activity of leukocytes and macrophages by traxanox sodium in mice and rats. PubMed: Proteins, nucleic acids and lipids of rat liver and spleen after experimental "chemical splenectomy" induced by intravenous injection of an ethyl palmitate emulsion. PubMed: Effect of a perfluorocarbon emulsion (Fluosol-DA) on reticuloendothelial system clearance function. PubMed: Experimental elimination of the splenic function by ethyl and methyl palmitate and significance of these substances from an immunological point of view. PubMed: Erythrocyte survival and haematocrit values in rats after i.v. application of ethyl palmitate and methyl palmitate emulsions. PubMed: Experimental elimination of the splenic function by an intravenous injection of ethyl palmitate emulsion in Wistar rats. PubMed: The dual role of macrophages in the sporozoite-induced malaria infection. A hypothesis. PubMed: The effect of intravenous injection of ethyl palmitate emulsion on sequestration of thermally damaged erythrocytes in rats with experimentally induced hypersplenism, and in normal rats. PubMed: Survival of human 51Cr erythrocytes in guinea-pigs. PubMed: Comparison of stationary phases in reversed-phase TLC for correlation between structure and biological response of probiotics. PubMed: Incorporation of [14C]-L-leucine in splenic and hepatic tissue of rats "chemically splenectomized" by ethyl palmitate. PubMed: 'Chemical' splenectomy and the number of haematopoietic stem cells. PubMed: Effects of ascorbic acid on glucose-6-phosphate dehydrogenase-deficient erythrocytes: studies in an animal model. PubMed: The inhibitory effect of methyl palmitate on heteroagglutinin formation in rats. PubMed: Oxygen-dependent circulation of sickle erythrocytes. PubMed: Effects of an i. v. injection of ethyl palmitate emulsion on nucleic acids and fat content of the liver. PubMed: Correction of the permeability defect in hereditary stomatocytosis by dimethyl adipimidate. PubMed: Gas-liquid chromatographic determination of beta-asarone in wines and flavors. PubMed: Autoantibody formation against spleen in rats 'chemically splenectomized' by ethyl palmitate. PubMed: The formation of heteroagglutinins in rats "chemically" splenectomized by ethyl palmitate, in comparison to animals surgically splenectomized. PubMed: Histological effects of lipids on the liver and spleen of mice. PubMed: Effects of simple lipids on macrophages in vitro. PubMed: Ethyl palmitate-induced "experimental splenectomy" in wistar rats. PubMed: Mechanism of ethyl palmitate and cobra venom factor enhancement of heterologous erythrocyte survival. PubMed: Studies on liver blood flow and phagocytic activity of reticuloendothelial system in dogs treated with ethyl palmitate. PubMed: The effect of ethyl palmitate on the liver blood flow and phagocytic activity of RES in dogs. PubMed: Studies on the effect of ethyl palmitate on the inhibition of erythrophagocytosis in dogs. PubMed: Ethyl palmitate-induced bartonellosis as an index of functional splenic ablation. PubMed: Radiological visualization of ethyl palmitate induced splenic atrophy. PubMed: Study of the mechanism of ethyl palmitate-induced splenic destruction. PubMed: The effects of a cobra venom factor and ethyl palmitate on the prolongation of survival of heterologous erythrocytes. PubMed: Ethyl palmitate-induced splenic destruction. PubMed: [Protective effect of ethyl palmitate in roentgen-irradiated mice].