Identification

Namedimethyl adipate
IUPACdimethyl hexanedioate
CAS Number627-93-0
EINECS211-020-6
FDA UNIIBY71RX0R62
Molecular FormulaC8 H14 O4
Molecular Weight174.19638000
MDL NumberMFCD00008469
Nikkaji NumberJ518E
Beilstein1707443
XlogP31.00 (est)

Regulatory

JECFA Food Flavoring1964 dimethyl adipate
FEMA Number4472
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)627-93-0 ; DIMETHYL ADIPATE

Physical Properties

Appearance colorless clear liquid (est)
Assay 98.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 1.05800 to 1.06100 @ 25.00 °C.
Pounds per Gallon - (est). 8.804 to 8.829
Refractive Index 1.42700 to 1.42800 @ 20.00 °C.
Melting Point 9.00 to 11.00 °C. @ 760.00 mm Hg
Boiling Point 109.00 to 110.00 °C. @ 14.00 mm Hg, 115.00 °C. @ 13.00 mm Hg
Acid Value 1.00 max. KOH/g
Vapor Pressure 0.073000 mmHg @ 25.00 °C. (est)
Vapor Density 6.1 ( Air = 1 )
Flash Point 225.00 °F. TCC ( 107.22 °C. )
logP (o/w) 1.030
Soluble in alcohol
Insoluble in water

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesplasticisers

Organoleptic Properties

Odor Strength low
Odor Description at 100.00 %.
Odor sample from Sigma-Aldrich
Taste Description bitter oily nut skin

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Oral/Parenteral Toxicityintraperitoneal-rat LD50 1809 uL/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryfood-contact surface of paper and paperboard
Recommendation for dimethyl adipate usage levels up tonot for fragrance use.
baked goods0.50000
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese5.00000
chewing gum-
condiments / relishes-
confectionery froastings-
egg products-
fats / oils5.00000
fish products-
frozen dairy-
fruit ices-
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products5.00000
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods5.00000
soft candy-
soups-
sugar substitutes-
sweet sauces-

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Potential Uses

emollients plasticisers skin conditioning

Natural Occurrence

not found in nature

Synonyms

adipic acid dimethyl ester adipic acid, dimethyl ester DBE 6 dibasic ester DBE-6 dibasic ester dimethyl 1,6-hexanedioate dimethyl adipate pure dimethyl hexane dioate 1,6- dimethyl hexane dioate dimethyl hexane-1,6-dioate dimethyl hexanedioate 1,6- dimethyl hexanedioate dimethyladipate hexane dioic acid 1,6-dimethyl ester hexane dioic acid dimethyl ester hexanedioic acid 1,6-dimethyl ester hexanedioic acid dimethyl ester hexanedioic acid, dimethyl ester PubMed: Catalytic oxidative cleavage of catechol by a non-heme iron(III) complex as a green route to dimethyl adipate. PubMed: Computational evidence for self-initiation in spontaneous high-temperature polymerization of methyl methacrylate. PubMed: Lipase-catalyzed dimethyl adipate synthesis: response surface modeling and kinetics. PubMed: Characterization of pyrolysis products from a biodiesel phenolic urethane binder. PubMed: [A new flavonoid from heartwood of Caesalpinia sappan]. PubMed: Chemoenzymatic synthesis and chemical recycling of sustainable polyurethanes. PubMed: Preparation and characterization of hydroxyapatite/poly(ethylene adipate) hybrid composites. PubMed: Enhancement of the Curie temperature by isomerization of diarylethene (DAE) for an organic-inorganic hybrid system: Co4(OH)7(DAE)0.5.3H2O. PubMed: Induction of heat shock protein 70 in rat olfactory epithelium by toxic chemicals: in vitro and in vivo studies. PubMed: Secondary metabolites from a Streptomyces strain isolated from Livingston Island, Antarctica. PubMed: Sites and mechanisms for uptake of gases and vapors in the respiratory tract. PubMed: Amphiphilic poly(ether ester amide) multiblock copolymers as biodegradable matrices for the controlled release of proteins. PubMed: Mixture risk assessment: a case study of Monsanto experiences. PubMed: Immunohistochemical localization of carboxylesterase in the nasal mucosa of rats. PubMed: A microscopic and ultrastructural evaluation of dibasic esters (DBE) toxicity in rat nasal explants. PubMed: Cytotoxicity of dibasic esters (DBE) metabolites in rat nasal explants. PubMed: Deposition of dibasic esters in the upper respiratory tract of the male and female Sprague-Dawley rat. PubMed: Carboxylesterase-dependent cytotoxicity of dibasic esters (DBE) in rat nasal explants. PubMed: Metabolism of dibasic esters by rat nasal mucosal carboxylesterase. PubMed: Anticonvulsant activity of deaminated analogues of glutamic acid diethyl ester (GDEE). PubMed: Gas chromatographic-mass spectrometric determination of adipate-based polymeric plasticizers in foods.