dextro-malic acid

D-hydroxybutanedioic acid

CAS: 636-61-3 C4 H6 O5 MW: 134.08782000

Identification

Namedextro-malic acid
IUPAC(2R)-2-hydroxybutanedioic acid
CAS Number636-61-3
EINECS211-262-2
FDA UNIIP750Y95K96
Molecular FormulaC4 H6 O5
Molecular Weight134.08782000
MDL NumberMFCD00004245
Nikkaji NumberJ14.674I
Beilstein1723540
XlogP3-1.30 (est)

Regulatory

Physical Properties

Appearance white crystalline powder (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 98.00 to 102.00 °C. @ 760.00 mm Hg
Boiling Point 306.00 to 307.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure 0.000007 mmHg @ 25.00 °C. (est)
Flash Point 308.00 °F. TCC ( 153.40 °C. ) (est)
logP (o/w) -1.370 (est)
Soluble in water, 3.64E+05 mg/L @ 20 °C (exp)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityoral-rabbit LDLo 5500 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryfood additive
Recommendation for dextro-malic acid usage levels up tonot for fragrance use.

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Potential Uses

None Found

Natural Occurrence

roselle fruit

Synonyms

D-(+)- apple acid butanedioic acid, 2-hydroxy-, (2R)- (R)-2- hydroxy-succinic acid (R)-2- hydroxybutane dioic acid (2R)-2- hydroxybutanedioic acid (R)- hydroxybutanedioic acid D- hydroxybutanedioic acid (2R)-2- hydroxysuccinic acid (R)-(+)- hydroxysuccinic acid (R)-2- hydroxysuccinic acid (+)-D- malic acid (R)- malic acid (R)-(+)- malic acid D- malic acid D-(+)- malic acid R- malic acid malic acid, D- PubMed: Analysis and quantification of ammonia-oxidizing bacteria community with amoA gene in sewage treatment plants. PubMed: Composition of pomegranate juice. PubMed: Total synthesis of the bicyclic depsipeptide HDAC inhibitors spiruchostatins A and B, 5''-epi-spiruchostatin B, FK228 (FR901228) and preliminary evaluation of their biological activity. PubMed: [Impact of phthalic acid easters on diversity of microbial community in soil]. PubMed: Inhibitory constituents of Euscaphis japonica on lipopolysaccharide-induced nitric oxide production in BV2 microglia. PubMed: Subulatin, an antioxidic caffeic acid derivative isolated from the in vitro cultured liverworts, Jungermannia subulata, Lophocolea heterophylla, and Scapania parvitexta. PubMed: Kinetics, stereospecificity, and expression of the malolactic enzyme. PubMed: Syntheses of (-)-Isocitric Acid Lactone and (-)-Homoisocitric Acid. A New Method of Conversion of Alkynylsilanes into the Alkynyl Thioether and Corresponding Carboxylic Acids. PubMed: Determination of D-malic acid in apple juice by liquid chromatography: collaborative study. PubMed: Detection of adulteration in apple juice by L-malic/total malic acid ratio: collaborative study. PubMed: High Content of Hydroxycinnamic Acids Esterified with (+)-D-Malic Acid in the Upper Parts of Fumaria officinalis1. PubMed: Transport of malic acid in the yeast Schizosaccharomyces pombe: evidence for a proton-dicarboxylate symport. PubMed: Transport of malic acid and other dicarboxylic acids in the yeast Hansenula anomala. PubMed: D-Malic enzyme of Pseudomonas fluorescens. PubMed: Malioxamycin, a new antibiotic with spheroplast-forming activity. II. Structural elucidation and total synthesis. PubMed: The absolute configuration of SU 23397: a novel neuroleptic agent. PubMed: Growth of Rhodopseudomonas capsulata on L- and D-malic acid. PubMed: The enzymic degradation of alkyl-substituted gentisates, maleates and malates. PubMed: Excretion of D-malic acid in the chicken.