dextro-menthol
D-menthol
Identification
| Name | dextro-menthol |
| IUPAC | (1S,2R,5S)-5-methyl-2-propan-2-ylcyclohexan-1-ol |
| CAS Number | 15356-60-2 |
| EINECS | 239-387-8 |
| FDA UNII | C6B1OE8P3W |
| Molecular Formula | C10 H20 O |
| Molecular Weight | 156.26860000 |
| MDL Number | MFCD00062983 |
| Beilstein | 1902292 |
| CoE Number | 63 |
Regulatory
| FEMA Number | 2665 |
| FDA | No longer provide for the use of these seven synthetic flavoring substances |
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 43.00 to 44.00 °C. @ 760.00 mm Hg |
| Boiling Point | 103.00 to 104.00 °C. @ 9.00 mm Hg |
| Vapor Pressure | 0.032000 mmHg @ 25.00 °C. (est) |
| Flash Point | 196.00 °F. TCC ( 91.11 °C. ) |
| logP (o/w) | 3.216 (est) |
| Soluble in | alcohol |
| Insoluble in | paraffin oil |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | perfuming agents |
Organoleptic Properties
| Odor Description | mentholic |
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | flavor and fragrance agents |
| RIFM Fragrance Material Safety Assessment | Search |
| maximum skin levels for fine fragrances | 0.2000 % and are based on the assumption that the fragrance mixture is used at 20% in a consumer product (IFRA Use Level Survey). (IFRA, 2006) |
| use level in formulae for use in cosmetics | 2.2500 % |
| Dermal Systemic Exposure in Cosmetic Products | 0.0573 mg/kg/day (IFRA, 2006) |
| baked goods | - |
| beverages(nonalcoholic) | - |
| beverages(alcoholic) | - |
| breakfast cereal | - |
| cheese | - |
| chewing gum | - |
| condiments / relishes | - |
| confectionery froastings | - |
| egg products | - |
| fats / oils | - |
| fish products | - |
| frozen dairy | - |
| fruit ices | - |
| gelatins / puddings | - |
| granulated sugar | - |
| gravies | - |
| hard candy | - |
| imitation dairy | - |
| instant coffee / tea | - |
| jams / jellies | - |
| meat products | - |
| milk products | - |
| nut products | - |
| other grains | - |
| poultry | - |
| processed fruits | - |
| processed vegetables | - |
| reconstituted vegetables | - |
| seasonings / flavors | - |
| snack foods | - |
| soft candy | - |
| soups | - |
| sugar substitutes | - |
| sweet sauces | - |
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Potential Uses
Natural Occurrence
Synonyms
cyclohexanol, 5-methyl-2-(1-methylethyl)-, (1S,2R,5S)-
(+)-
menthol
(1S,2R,5S)-(+)-
menthol
D-
menthol
menthol, (1S,3S,4R)-(+)-
menthol-d dist.
(1S,2R,5S)-5-
methyl-2-propan-2-ylcyclohexan-1-ol
Info:
menthol
PubMed:
Effects of d-menthol stress on the growth of and microcystin release by the freshwater cyanobacterium Microcystis aeruginosa FACHB-905.
PubMed:
The stereoisomers of menthol in selected tobacco products. A brief report.
PubMed:
Different effects of l- and d-menthol on the microstructure of ceramide 5/cholesterol/palmitic acid bilayers.
PubMed:
Fragrance material review on d-menthol.
PubMed:
Esters of pyromellitic acid. Part II. Esters of chiral alcohols: para pyromellitate diesters as a novel class of resolving agents and use of pyromellitates as duplicands for chiral purification.
PubMed:
Identification of the L-menthol binding site in guinea-pig lung membranes.
PubMed:
The contribution of cytotoxicity to DNA-effects in the single cell gel test (comet assay).
PubMed:
The effects of D and L isomers of menthol upon nasal sensation of airflow.
PubMed:
Menthol modulates oral sensations of warmth and cold.