alpha-naphthyl methyl ether
naphthalene, 1-methoxy-
Identification
| Name | alpha-naphthyl methyl ether |
| CAS Number | 2216-69-5 |
| EINECS | 218-696-1 |
| FDA UNII | DG2EOL57LF |
| Molecular Formula | C11 H10 O |
| Molecular Weight | 158.19990000 |
| MDL Number | MFCD00003924 |
| Nikkaji Number | J7.365B |
| Beilstein | 0774884 |
| XlogP3 | 3.60 (est) |
Regulatory
| DG SANTE Food Flavourings | 04.075 1-methoxynaphthalene |
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Specific Gravity | 1.09300 to 1.09900 @ 25.00 °C. |
| Pounds per Gallon - (est). | 9.095 to 9.145 |
| Refractive Index | 1.62200 to 1.62800 @ 20.00 °C. |
| Melting Point | 6.00 °C. @ 760.00 mm Hg |
| Boiling Point | 135.00 to 137.00 °C. @ 12.00 mm Hg, 270.00 °C. @ 760.00 mm Hg |
| Vapor Pressure | 0.013000 mmHg @ 25.00 °C. (est) |
| Flash Point | > 230.00 °F. TCC ( > 110.00 °C. ) |
| logP (o/w) | 3.450 |
| Soluble in | alcohol |
| Insoluble in | water |
No sensory data available
Safety Information
| Preferred SDS | View |
| European information | Most important hazard(s): |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | flavoring agents |
| Recommendation for alpha-naphthyl methyl ether usage levels up to | not for fragrance use. |
| Maximised Survey-derived Daily Intakes (MSDI-EU) | 0.061 (μg/capita/day) |
| Modified Theoretical Added Maximum Daily Intake (mTAMDI) | 3200 (μg/person/day) |
| Threshold of Concern | 90 (μg/person/day) |
| Structure Class | III |
| Dairy products, excluding products of category 02.0 (01.0) | 3.00000 |
| Fats and oils, and fat emulsions (type water-in-oil) (02.0) | 2.00000 |
| Edible ices, including sherbet and sorbet (03.0) | 3.00000 |
| Processed fruit (04.1) | 2.00000 |
| Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2) | - |
| Confectionery (05.0) | 10.00000 |
| Chewing gum (05.3) | - |
| Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0) | 5.00000 |
| Bakery wares (07.0) | 10.00000 |
| Meat and meat products, including poultry and game (08.0) | 2.00000 |
| Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0) | 2.00000 |
| Eggs and egg products (10.0) | - |
| Sweeteners, including honey (11.0) | - |
| Salts, spices, soups, sauces, salads, protein products, etc. (12.0) | 5.00000 |
| Foodstuffs intended for particular nutritional uses (13.0) | 10.00000 |
| Non-alcoholic ("soft") beverages, excl. dairy products (14.1) | 3.00000 |
| Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2) | 10.00000 |
| Ready-to-eat savouries (15.0) | 15.00000 |
| Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0) | 5.00000 |
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Potential Uses
Natural Occurrence
Synonyms
1-
methoxy naphthalene
1-
methoxy-naphthalene
1-
methoxynaphthalen
1-
methoxynaphthalene
alpha-
methoxynaphthalene
1-
methoxynapthalene
methyl 1-naphthyl ether
methyl naphthalen-1-yl ether
naphthalene, 1-methoxy-
PubMed:
Synthesis of 2-acetyl-1,4-dimethoxynaphthalene, a potential intermediate for disubstituted naphtho[2,3,c]pyran-5,10-dione.
PubMed:
A convergent total synthesis of the telomerase inhibitor (±)-γ-rubromycin.
PubMed:
Effects of methoxy and formyl substituents on the energetics and reactivity of α-naphthalenes: a calorimetric and computational study.
PubMed:
Peroxygenase activity of cytochrome c peroxidase and three apolar distal heme pocket mutants: hydroxylation of 1-methoxynaphthalene.
PubMed:
The rates of charge separation and energy destructive charge recombination processes within an organic dyad in presence of metal-semiconductor core shell nanocomposites.
PubMed:
Experimental (FT-IR and FT-Raman), electronic structure and DFT studies on 1-methoxynaphthalene.
PubMed:
Production of novel antioxidative prenyl naphthalen-ols by combinational bioconversion with dioxygenase PhnA1A2A3A4 and prenyltransferase NphB or SCO7190.
PubMed:
Toxicity and inhibition of feeding and tunneling response of naphthalene and 10 derivatives on the formosan subterranean termite (Isoptera: Rhinotermitidae).
PubMed:
Aromatic C-H bond hydroxylation by P450 peroxygenases: a facile colorimetric assay for monooxygenation activities of enzymes based on Russig's blue formation.
PubMed:
Development of a nanocomposite system by combining an organic dyad 1-(4-chloro-phenyl)-3-(4-methoxy-naphthalen-1-yl)-Propenone with semiconductor TiO2 nanoparticles.
PubMed:
Alkali-metal-mediated manganation(II) of naphthalenes: constructing metalla-anthracene and metalla-phenanthrene structures.
PubMed:
Comparative studies on the DNA-binding properties of linear and angular dibenzoquinolizinium ions.
PubMed:
Biotransformation of 1-naphthol by a strictly aquatic fungus.
PubMed:
An efficient carbonyl-alkene metathesis of bicyclic oxetanes: photoinduced electron transfer reduction of the Paternò-Büchi adducts from 2,3-dihydrofuran and aromatic aldehydes.
PubMed:
Reductive PET cycloreversion of oxetanes: singlet multiplicity, regioselectivity, and detection of olefin radical anion.
PubMed:
[Determination of alpha-methoxynaphthalene by reversed-phase high performance liquid chromatographic method].
PubMed:
NMR and calculational studies on the regioselective lithiation of 1-methoxynaphthalene.
PubMed:
Biotransformation of phenanthrene and 1-methoxynaphthalene with Streptomyces lividans cells expressing a marine bacterial phenanthrene dioxygenase gene cluster.
PubMed:
Photolysis of ((3-(Trimethylsilyl)propoxy)phenyl)phenyliodonium salts in the presence of 1-naphthol and 1-methoxynaphthalene
PubMed:
Substrate specificity, regiospecificity and stereospecificity of halogenation reactions catalyzed by non-heme-type bromoperoxidase of Corallina pilulifera.
PubMed:
Disposition of a new alkylating agent [14C]mitoclomine (N,N-bis(2'-chloroethyl)4-amino-2-methyl-1-methoxy-naphthalene).