dextro-phenyl alanine

D-a-amino-b-phenylpropionic acid

CAS: 673-06-3 C9 H11 N O2 MW: 165.19207000

Identification

Namedextro-phenyl alanine
IUPAC(2R)-2-amino-3-phenylpropanoic acid
CAS Number673-06-3
EINECS211-603-5
FDA UNII032K16VRCU
Molecular FormulaC9 H11 N O2
Molecular Weight165.19207000
MDL NumberMFCD00004270
Nikkaji NumberJ9.200B
Beilstein2804068
XlogP3-1.50 (est)

Regulatory

Physical Properties

Appearance white needles or prisms (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 283.00 °C. @ 760.00 mm Hg (est)
Boiling Point 273.00 to 276.00 °C. @ 760.00 mm Hg
Vapor Pressure 1.760000 mmHg @ 25.00 °C. (est)
Flash Point 284.00 °F. TCC ( 139.80 °C. ) (est)
logP (o/w) 0.235 (est)
Soluble in water, 2.82E+04 mg/L @ 16C (exp)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityoral-human TDLo 500 mg/kg/5W-I
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements', 'LUNGS, THORAX, OR RESPIRATION: DYSPNEA\nBEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)']

Safety in Use

Categorypharmaceuticals / chemical synthisis
Recommendation for dextro-phenyl alanine usage levels up tonot for fragrance use.
Recommendation for dextro-phenyl alanine flavor usage levels up tonot for flavor use.

BOC Sciences

Best of Chemicals Supplier

Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...

View All Website 1-631-485-4226 account@bocsci.com

Glentham Life Sciences Ltd

The Chemical, Biochemical & Research Essentials Supplier

Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK.

View All Website +44 (0) 1225 667798 info@glentham.com

Penta International Corporation

Chemistry innovation

At Penta, our products and services help businesses do business better.

View All Website (973) 740-2300 lisaa@pentamfg.com

TCI AMERICA

Moving Your Chemistry Forward

We continuously strive to advance our technology.

View All Website 1-800-423-8616 Sales-US@TCIchemicals.com;

Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

(2R)-2- amino-3-phenylpropanoic acid (R)-2- amino-3-phenylpropionic acid D-a- amino-b-phenylpropionic acid D- fenylalanine (R)-(+)- phenyl alanine (R)- phenylalanine (R)-(+)- phenylalanine D- phenylalanine D-(+)- phenylalanine D- phenylalaninol sabiden PubMed: Flavonolignans and Other Constituents from Lepidium meyenii with Activities in Anti-inflammation and Human Cancer Cell Lines. PubMed: Effects of conversion of the zinc-binding motif sequence of thermolysin, HEXXH, to that of dipeptidyl peptidase III, HEXXXH, on the activity and stability of thermolysin. PubMed: Characterization of ergothionase from Burkholderia sp. HME13 and its application to enzymatic quantification of ergothioneine. PubMed: Relative fasting bioavailability of two formulations of nateglinide 60 mg in healthy male Chinese volunteers: an open-label, randomized-sequence, single-dose, two-way crossover study. PubMed: The use of a food supplementation with D-phenylalanine, L-glutamine and L-5-hydroxytriptophan in the alleviation of alcohol withdrawal symptoms. PubMed: [Intestinal absorption and secretion mechanism of carboxylate drugs]. PubMed: Allelic variation of the Tas1r3 taste receptor gene selectively affects taste responses to sweeteners: evidence from 129.B6-Tas1r3 congenic mice. PubMed: Improvement in performance of affinity gels containing Gly-D-Phe as a ligand to thermolysin due to increasing the spacer chain length. PubMed: Exenatide: a new option for the treatment of type 2 diabetes. PubMed: Gas chromatographic determination and mechanism of formation of D-amino acids occurring in fermented and roasted cocoa beans, cocoa powder, chocolate and cocoa shell. PubMed: Performance of D-amino acid oxidase in presence of ionic liquids. PubMed: Characterization of Gly-D-Phe, Gly-L-Leu, and D-Phe as affinity ligands to thermolysin. PubMed: A new strategy for the selective determination of D-amino acids: enzymatic and chemical modifications for pre-column derivatization. PubMed: Distribution and characteristics of D-amino acid and D-aspartate oxidases in fish tissues. PubMed: The tripeptide FEG ameliorates systemic inflammatory responses to rat intestinal anaphylaxis. PubMed: Sweetener preference of C57BL/6ByJ and 129P3/J mice. PubMed: Importance of postprandial glucose control. PubMed: [Pharmacological properties of nateglinide, rapid-onset/short-duration insulinotropic agent, in the treatment of type 2 diabetes]. PubMed: Stabilization of D-amino acid oxidase and catalase in permeabilized Rhodotorula gracilis cells and its application for the preparation of alpha-ketoacids*. PubMed: Chemistry, nutrition, and microbiology of D-amino acids. PubMed: Calcium-deprived rats avoid sweet compounds. PubMed: Effect of food on the bioavailability of SDZ DJN 608, an oral hypoglycemic agent, from a tablet and a liquid-filled capsule in the dog. PubMed: Suppression of meal size by intestinal nutrients is eliminated by celiac vagal deafferentation. PubMed: The genetic basis of preference for sweet substances among inbred strains of mice: preference ratio phenotypes and the alleles of the Sac and dpa loci. PubMed: Separation of amino-acid enantiomers using micellar-enhanced ultrafiltration. PubMed: Formation, nutritional value, and safety of D-amino acids. PubMed: Treatment of hyperactive children with D-phenylalanine. PubMed: The availability of D-phenylalanine and DL-phenylalanine. PubMed: The nutritive value and safety of D-phenylalanine and D-tyrosine in mice. PubMed: Racemization of aspartic acid and phenylalanine in the sweetener aspartame at 100 degrees C. PubMed: Feeding, drinking, urine osmolality in DI Brattleboro rats: changes by morphine, naloxone, D-amino acids, prolyl-leucyl-glycinamide (PLG). PubMed: Modulation of deprivation-induced food intake by D-phenylalanine. PubMed: The effect of gastric loads of sugars and amino acids on milk intake of suckling pigs. PubMed: Ontogeny of cholecystokinin satiety in rats. PubMed: Cholecystokinin and satiety in rats and rhesus monkeys. PubMed: Cholecystokinin-decreased food intake in rhesus monkeys.