lawsone
1,4-naphthalenedione, 2-hydroxy-
Identification
| Name | lawsone |
| CAS Number | 83-72-7 |
| EINECS | 201-496-3 |
| FDA UNII | TLH4A6LV1W |
| Molecular Formula | C10 H6 O3 |
| Molecular Weight | 174.15542000 |
| MDL Number | MFCD00001678 |
| Nikkaji Number | J4.642F |
| Beilstein | 1565260 |
Regulatory
Physical Properties
| Appearance | yellow powder (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 194.00 °C. @ 760.00 mm Hg |
| Boiling Point | 352.40 °C. @ 760.00 mm Hg (est) |
| Flash Point | 358.00 °F. TCC ( 181.10 °C. ) (est) |
| logP (o/w) | 1.380 |
| Soluble in | water, 3895 mg/L @ 25 °C (est) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | hair dyeing agents |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | intraperitoneal-mouse LD50 100 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | hair dyeing agents |
| Recommendation for lawsone usage levels up to | not for fragrance use. |
| Recommendation for lawsone flavor usage levels up to | not for flavor use. |
BOC Sciences
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Potential Uses
Natural Occurrence
Synonyms
c.i. 75480
C.I. natural orange 6
2-
hydroxy-1,4-naphthalenedione
2-
hydroxy-1,4-naphthoquinone
2-
hydroxy-1,4-naphthoquinone
2-
hydroxynaphthalene-1,2-dione
2-
hydroxynaphthoquinone
lawson
mehendi
1,4-
naphthalenedione, 2-hydroxy-
1,4-
naphthoquinone, 2-hydroxy-
natural orange 6 (c.i. 75480)
PubMed:
Antifungal activity of the Algerian Lawsonia inermis (henna).
PubMed:
Rapid determination of para-phenylenediamine by gas chromatography-mass spectrometry with selected ion monitoring in henna-containing cosmetic products.
PubMed:
Structure-activity relationships of anthraquinones on the suppression of DNA-binding activity of the aryl hydrocarbon receptor induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
PubMed:
Absorption of lawsone through human skin.
PubMed:
Determination of some organochlorine compounds in herbal colouring agent henna (Lawsonia inermis) and in tea (Thea sinensis).
PubMed:
Selective growth-inhibiting effects of compounds identified in Tabebuia impetiginosa inner bark on human intestinal bacteria.
PubMed:
[Cosmetic colorants. Toxicology and regulation].
PubMed:
Toxicity and human health risk of hair dyes.
PubMed:
Differential toxicity of juglone (5-hydroxy-1,4-naphthoquinone) and related naphthoquinones to saturniid moths.
PubMed:
An investigation of dye reduction by food-borne bacteria.