salicin
saligenin-b-D-glucopyranoside
Identification
| Name | salicin |
| CAS Number | 138-52-3 |
| EINECS | 205-331-6 |
| FDA UNII | 4649620TBZ |
| Molecular Formula | C13 H18 O7 |
| Molecular Weight | 286.28086000 |
| MDL Number | MFCD00006590 |
| Nikkaji Number | J5.634K |
| Beilstein | 089593 |
| XlogP3 | -1.20 (est) |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 197.00 to 200.00 °C. @ 760.00 mm Hg |
| Boiling Point | 549.09 °C. @ 760.00 mm Hg (est) |
| Flash Point | 547.00 °F. TCC ( 285.90 °C. ) (est) |
| logP (o/w) | -1.232 (est) |
| Soluble in | water, 4.00E+04 mg/L @ 25 °C (exp) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | skin conditioning |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | intraperitoneal-mouse LD > 500 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | cosmetic agents |
| Recommendation for salicin usage levels up to | not for fragrance use. |
| Recommendation for salicin flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
benzyl alcohol, o-hydroxy-, o-glucoside
b-D-
glucopyranoside, 2-(hydroxymethyl)phenyl
a-
hydroxy-o-tolyl b-D-glucopyranoside
(2R,3S,4S,5R,6S)-2-
hydroxymethyl-6-(2-hydroxymethyl-phenoxy)-tetrahydro-pyran-3,4,5-triol
(2S,4S,5S,3R,6R)-6-(
hydroxymethyl)-2-[2-(hydroxymethyl)phenoxy]-2H-3,4,5,6-tet rahydropyran-3,4,5-triol
(2S,4S,5S,3R,6R)-6-(
hydroxymethyl)-2-[2-(hydroxymethyl)phenoxy]-2H-3,4,5,6-tetrahydropyran-3,4,5-triol
(2R,3S,4S,5R,6S)-2-(
hydroxymethyl)-6-(2-(hydroxymethyl)phenoxy)tetrahydro-2H-pyran-3,4,5-triol
(2R,3S,4S,5R,6S)-2-(
hydroxymethyl)-6-[2-(hydroxymethyl)phenoxy]oxane-3,4,5-triol
(2R,3S,4S,5R,6S)-2-(
hydroxyméthyl)-6-[2-(hydroxyméthyl)phénoxy]tétrahydro-2H-pyran-3,4,5-triol
o-(
hydroxymethyl)phenyl β-D-glucopyranoside
2-(
hydroxymethyl)phenyl-b-D-glucopyranoside
D-(-)-
salicin
salicoside
salicyl alcohol glucoside
salicylalcohol glucoside
saligenin glucoside
saligenin-b-D-glucopyranoside
PubMed:
The study of interactions between active compounds of coffee and willow (Salix sp.) bark water extract.
PubMed:
Hydroxybenzoic acid isomers and the cardiovascular system.
PubMed:
Tissue-specific transcript profiling for ABC transporters in the sequestering larvae of the phytophagous leaf beetle Chrysomela populi.
PubMed:
Recombinant expression and characterization of the cytoplasmic rice β-glucosidase Os1BGlu4.
PubMed:
Comparisons of contact chemoreception and food acceptance by larvae of polyphagous Helicoverpa armigera and oligophagous Bombyx mori.
PubMed:
Hydrolysis of aromatic β-glucosides by non-pathogenic bacteria confers a chemical weapon against predators.
PubMed:
Pectinatus sottacetonis sp. nov., isolated from a commercial pickle spoilage tank.
PubMed:
High-performance liquid chromatographic analysis of biogenic amines in pharmaceutical products containing Citrus aurantium.
PubMed:
Biochemical properties of a novel glycoside hydrolase family 1 β-glucosidase (PtBglu1) from Paecilomyces thermophila expressed in Pichia pastoris.
PubMed:
Evaluation of the microbial community in industrial rye sourdough upon continuous back-slopping propagation revealed Lactobacillus helveticus as the dominant species.
PubMed:
A rapid and simple screening method of Cronobacter spp. in cell suspension and tofu.
PubMed:
Toxin profile, antibiotic resistance, and phenotypic and molecular characterization of Bacillus cereus in Sunsik.
PubMed:
Genetic analysis of the electrophysiological response to salicin, a bitter substance, in a polyphagous strain of the silkworm Bombyx mori.
PubMed:
Functional diversity of bitter taste receptor TAS2R16 in primates.
PubMed:
Prevalence, phenotypic traits and molecular characterization of emetic toxin-producing Bacillus cereus strains isolated from human stools in Korea.
PubMed:
Lactobacillus brantae sp. nov., isolated from faeces of Canada geese (Branta canadensis).
PubMed:
A new cost-effective, selective and differential medium for the isolation of Cronobacter spp.
PubMed:
Comparison of three thermostable β-glucosidases for application in the hydrolysis of soybean isoflavone glycosides.
PubMed:
Purification and characterization of an intracellular beta-glucosidase from the protoplast fusant of Aspergillus oryzae and Aspergillus niger.
PubMed:
Anti-acetylcholinesterase and antioxidant assets of the major components (salicin, amentoflavone, and chlorogenic acid) and the extracts of Viburnum opulus and Viburnum lantana and their total phenol and flavonoid contents.
PubMed:
The human bitter taste receptor, hTAS2R16, discriminates slight differences in the configuration of disaccharides.
PubMed:
Comparison of enterotoxin production and phenotypic characteristics between emetic and enterotoxic Bacillus cereus.
PubMed:
Characterization of the beta-D-glucopyranoside binding site of the human bitter taste receptor hTAS2R16.
PubMed:
Ogataea pignaliae sp. nov., the teleomorph of Candida pignaliae.
PubMed:
Gustatory responsiveness to six bitter tastants in three species of nonhuman primates.
PubMed:
pH-Dependent inhibition of the human bitter taste receptor hTAS2R16 by a variety of acidic substances.
PubMed:
Structural analogues of homoeriodictyol as flavor modifiers. Part III: short chain gingerdione derivatives.
PubMed:
Characterization of a thermostable extracellular beta-glucosidase with activities of exoglucanase and transglycosylation from Paecilomyces thermophila.
PubMed:
Lactobacillus ghanensis sp. nov., a motile lactic acid bacterium isolated from Ghanaian cocoa fermentations.
PubMed:
Cryptococcus anemochoreius sp. nov., a novel anamorphic basidiomycetous yeast isolated from the atmosphere in central South Africa.
PubMed:
Sequestration of plant-derived phenolglucosides by larvae of the leaf beetle Chrysomela lapponica: thioglucosides as mechanistic probes.
PubMed:
Molecular typing and virulence markers of Yersinia enterocolitica strains from human, animal and food origins isolated between 1968 and 2000 in Brazil.
PubMed:
Conflicting demands on detoxification pathways influence how common brushtail possums choose their diets.
PubMed:
Potential role for gut microbiota in cell wall digestion and glucoside detoxification in Tenebrio molitor larvae.
PubMed:
Stable isotope characterization of the ortho-oxygenated phenylpropanoids: coumarin and melilotol.
PubMed:
Application of hydrophilic interaction liquid chromatography/comparative taste dilution analysis for identification of a bitter inhibitor by a combinatorial approach based on Maillard reaction chemistry.
PubMed:
Evaluation of bitter masking flavanones from Herba Santa (Eriodictyon californicum (H. and A.) Torr., Hydrophyllaceae).
PubMed:
Semi-industrial isolation of salicin and amygdalin from plant extracts using slow rotary counter-current chromatography.
PubMed:
Emetic toxin formation of Bacillus cereus is restricted to a single evolutionary lineage of closely related strains.
PubMed:
Differentiation of extractive and synthetic salicin. The 2H aromatic pattern of natural 2-hydroxybenzyl alcohol.
PubMed:
[Life threatening intestinal bleeding in a Bearded Collie associated with a food supplement for horses].
PubMed:
Catabolite repression and virulence gene expression in Listeria monocytogenes.
PubMed:
Optimization of carbohydrate silylation for gas chromatography.
PubMed:
Staphylococcus equorum subsp. linens, subsp. nov., a starter culture component for surface ripened semi-hard cheeses.
PubMed:
Purification and characterization of vanilla bean (Vanilla planifolia Andrews) beta-D-glucosidase.
PubMed:
Modification of an approved medium for fecal coliform detection in seawater: A-1 medium minus salicin.
PubMed:
Characterization of an extracellular salicyl alcohol oxidase from larval defensive secretions of Chrysomela populi and Phratora vitellinae (Chrysomelina).
PubMed:
The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides.
PubMed:
Weissella kimchii sp. nov., a novel lactic acid bacterium from kimchi.
PubMed:
Evaluation of sorbitol-salicin MacConkey medium containing cefixime and tellurite (CT-SSMAC medium) for isolation of Escherichia coli O157:H7 from raw vegetables.
PubMed:
Selective adaptation to noxious foods by a herbivorous insect.
PubMed:
Purification and characterization of a beta-glucosidase from Citrus sinensis var. Valencia fruit tissue.
PubMed:
Differences in host use efficiency of larvae of a generalist moth, Operophtera brumata on three chemically divergent Salix species.
PubMed:
Does excretion of secondary metabolites always involve a measurable metabolic cost? Fate of plant antifeedant salicin in common brushtail possum, Trichosurus vulpecula.
PubMed:
[Development of chromogenic agar medium for isolation of enterohaemorrhagic Escherichia coli O26].
PubMed:
Heterologous Expression of a Candida molischiana Anthocyanin-beta-glucosidase in a Wine Yeast Strain.
PubMed:
Plant secondary metabolites as mammalian feeding deterrents: separating the effects of the taste of salicin from its post-ingestive consequences in the common brushtail possum (Trichosurus vulpecula).
PubMed:
Lactobacillus nagelii sp. nov., an organism isolated from a partially fermented wine.
PubMed:
Evaluation of media for selective enumeration of Streptococcus thermophilus, Lactobacillus delbrueckii ssp. bulgaricus, Lactobacillus acidophilus, and bifidobacteria.
PubMed:
[Characteristics of Yersinia strains from clinical material and from other sources. I. Selected biochemical properties].
PubMed:
Yeast succession in the Amazon fruit Parahancornia amapa as resource partitioning among Drosophila spp.
PubMed:
The repression of listeriolysin O expression in Listeria monocytogenes by the phenolic beta-D-glucoside, arbutin.
PubMed:
Toxins in chrysomelid beetles Possible evolutionary sequence from de novo synthesis to derivation from food-plant chemicals.
PubMed:
[Serotype characterization of Escherichia coli potentially producing enterotoxins in foods].
PubMed:
Biochemical differentiation between enterotoxigenic heat-sensitive and heat-resistant Clostridium perfringens strains.
PubMed:
Chemosensitivity of lobster,Homarus americanus, to secondary plant compounds: Unused receptor capabilities.
PubMed:
The incidence of Bacillus cereus in foods in Central Thailand.
PubMed:
Biochemical characteristics and identification of Enterobacteriaceae isolated from meats.
PubMed:
Yersinia enterocolitica biotype 1 in South Africa.
PubMed:
Enrichment methods for recovery of Yersinia enterocolitica from foods and raw milk.
PubMed:
Numerical classification of Yersinia enterocolitica and relationship between its subdivision and pathogenicity.
PubMed:
The ability of some Yersinia enterocolitica strains to invade HeLa cells.