2-ethyl pyrazine

2-ethylpyrazine

CAS: 13925-00-3 C6 H8 N2 MW: 108.14376000 nutty nutty

Identification

Name2-ethyl pyrazine
IUPAC2-ethylpyrazine
CAS Number13925-00-3
EINECS237-691-5
FDA UNII0QO4LUV16Z
Molecular FormulaC6 H8 N2
Molecular Weight108.14376000
MDL NumberMFCD00006149
Nikkaji NumberJ27.869F
Beilstein0108200
CoE Number2213
XlogP30.70 (est)

Regulatory

JECFA Food Flavoring762 2-ethylpyrazine
DG SANTE Food Flavourings14.022 2-ethylpyrazine
FEMA Number3281
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)13925-00-3 ; 2-ETHYLPYRAZINE

Physical Properties

Appearance colorless to pale yellow clear liquid (est)
Assay 98.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 0.99500 to 0.99800 @ 20.00 °C.
Pounds per Gallon - (est). 8.289 to 8.314
Refractive Index 1.49800 to 1.50000 @ 20.00 °C.
Boiling Point 152.00 to 153.00 °C. @ 760.00 mm Hg, 122.00 to 124.00 °C. @ 90.00 mm Hg
Vapor Pressure 4.007000 mmHg @ 25.00 °C. (est)
Flash Point 109.00 °F. TCC ( 42.78 °C. )
logP (o/w) 0.690
Soluble in alcohol
Insoluble in water

Organoleptic Properties

Odor Description
at 1.00 % in dipropylene glycol.
at 1.00 %.
Musty, nutty, buttery, peanut
Peanut Butter, Woody, Musty
NUTTY, COFFEE, ROAST, MEAT
Taste Description
at 10.00 ppm.
chocolate-peanut

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavor and fragrance agents
RIFM Fragrance Material Safety AssessmentSearch
Recommendation for 2-ethyl pyrazine usage levels up to0.1000 % in the fragrance concentrate.
Maximised Survey-derived Daily Intakes (MSDI-EU)2.20 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA)6.00 (μg/capita/day)
Structure ClassII
baked goods-
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum-
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy-
fruit ices-
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

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Potential Uses

FL bread FR butter FL chocolate cocoa FR coffee FL nut FL peanut butter FR woody

Natural Occurrence

asparagus beef boiled beef PMC bread PMC chicory root oil @ 0.028% Data cocoa coffee PMC fenugreek seed filbert fish PMC malt PMC peanut pork cooked pork PMC potato baked potato shrimp PMC tea leaf

Synonyms

2- ethyl pyrazine, kosher 2- ethyl-1,4-diazine ethyl-2 pyrazine 2- ethyl-pyrazine 2- ethylpyrazine 2- ethylpyrazine 10% in ethyl alcohol 2- ethylpyrazine 10% in ethyl alcohol, kosher moldin pyrazine, 2-ethyl- US Patents: 3,931,166 - Certain 2,5-dimethyl-3-thiopyrazines PubMed: Key aroma compounds in roasted in-shell peanuts. PubMed: Determination of the alkylpyrazine composition of coffee using stable isotope dilution-gas chromatography-mass spectrometry (SIDA-GC-MS). PubMed: Evaluation of process parameters governing the aroma generation in three hazelnut cultivars (Corylus avellana L.) by correlating quantitative key odorant profiling with sensory evaluation. PubMed: Convenient synthesis of stable deuterium-labeled alkylpyrazines for use in stable isotope dilution assays. PubMed: 2-Ethyl-3,5,6-triphenyl-pyrazine. PubMed: GC-MS based metabolomics for rapid simultaneous detection of Escherichia coli O157:H7, Salmonella Typhimurium, Salmonella Muenchen, and Salmonella Hartford in ground beef and chicken. PubMed: Identification of potent odourants in wine and brewed coffee using gas chromatography-olfactometry and comprehensive two-dimensional gas chromatography. PubMed: Similar odorants elicit different behavioral and physiological responses, some supersustained. PubMed: Phorid fly, Pseudacteon tricuspis, response to alkylpyrazine analogs of a fire ant, Solenopsis invicta, alarm pheromone. PubMed: Isolation of a pyrazine alarm pheromone component from the fire ant, Solenopsis invicta. PubMed: Strategy for the identification of key odorants: application to shrimp aroma. PubMed: Safety assessment of 2-ethyl-3,(5 or 6) dimethylpyrazine as a food ingredient. PubMed: Closed-pore crystal capable of adsorbing CO2 onto isolated cavities generated by disorderly mixing of substituents on host skeleton. PubMed: Structural study of silver(I) sulfonate complexes with pyrazine derivatives. PubMed: Degradation of 2,5-dimethylpyrazine by Rhodococcus erythropolis strain DP-45 isolated from a waste gas treatment plant of a fishmeal processing company. PubMed: Investigations on the synthesis, structures, and properties of new copper(I) 2,3-dimethylpyrazine coordination compounds. PubMed: Characterization of aroma compounds of chinese "Wuliangye" and "Jiannanchun" liquors by aroma extract dilution analysis. PubMed: Identification of components responsible for the odor of cigar smoker's breath. PubMed: The chafer pheromone buibuilactone and ant pyrazines are also produced by marine bacteria. PubMed: Pyrazine derivatives in cigarette smoke inhibit hamster oviductal functioning. PubMed: Growth and angiogenesis are inhibited in vivo in developing tissues by pyrazine and its derivatives. PubMed: Chemoenzymatic synthesis of aroma active 5,6-dihydro- and tetrahydropyrazines from aliphatic acyloins produced by baker's yeast. PubMed: Critical comparison of three olfactometric methods for the identification of the most potent odorants in cooked mussels (Mytilus edulis). PubMed: Volatile flavor components of rice cakes. PubMed: Pyrazine formation from serine and threonine. PubMed: Effects of roasting on pyrazine contents and oxidative stability of red pepper seed oil prior to its extraction. PubMed: Synthesis and in vitro trypanocidal activity of some novel iron chelating agents. PubMed: Quantitative analysis of alkylpyrazines in regular- and low-fat commercial peanut butter preparations.