carboxymethyl cellulose

carboxymethylcellulose

CAS: 9000-11-7 C8 H16 O8 MW: 240.20912000

Identification

Namecarboxymethyl cellulose
IUPACacetic acid; 2,3,4,5,6-pentahydroxyhexanal
CAS Number9000-11-7
FDA UNII05JZI7B19X
Molecular FormulaC8 H16 O8
Molecular Weight240.20912000
MDL NumberMFCD00149018

Regulatory

FDA/DG SANTE Petitions, Reviews, Notices1973
DG SANTE Food Contact Materialscarboxymethylcellulose
FEMA Number2239
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)9000-11-7 ; CARBOXYMETHYL CELLULOSE
FDA RegulationFDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS

Physical Properties

Appearance white powder (est)
Assay 96.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 527.00 to 528.00 °C. @ 760.00 mm Hg
Flash Point 548.00 °F. TCC ( 286.67 °C. )
logP (o/w) -3.169 (est)
Shelf Life 24.00 month(s) or longer if stored properly.
Storage store in cool, dry place in tightly sealed containers, protected from heat and light.
Soluble in alcohol
Insoluble in water

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesbinding agents

Organoleptic Properties

Odor Strength none
Odor Description at 100.00 %.

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Oral/Parenteral Toxicityoral-rat LD > 5000 mg/kg
Dermal Toxicityskin-rabbit LD50 > 5000 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryfood contact resinous and polymeric coatings
Recommendation for carboxymethyl cellulose usage levels up tonot for fragrance use.
baked goods-
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum-
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy-
fruit ices-
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

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Potential Uses

binding agents bulking agents gel forming agents viscosity controlling agents

Natural Occurrence

not found in nature

Synonyms

acetic acid, hydroxy-, cellulose ether acetic acid; 2,3,4,5,6-pentahydroxyhexanal apergel apeyel bermocell CMC carboximethylcellulosum carboxy methyl cellulose carboxymethyl cellulose (CMC) food-grade gums – Akucell carboxymethyl cellulose ether carboxymethylated cellulose pulp carboxymethylcellulose carboxymethylcellulosum cellulose carboxymethyl ether cellulose carboxymethylate cellulose, carboxymethyl ether cellulose, ether with glycolic acid CM-cellulose CMC colloresine croscarmellose duodcel glycocel TA glycolic acid cellulose ether KMTs opticellulose syrup 2600 opticellulose syrup 500 ticalose PubMed: The primate amygdala: Neuronal representations of the viscosity, fat texture, temperature, grittiness and taste of foods. PubMed: Volatile flavor analysis and sensory evaluation of custard desserts varying in type and concentration of carboxymethyl cellulose. PubMed: beta-D(+) glucose-glucose oxidase-catalase for use as an antioxidant system. PubMed: Flavor avoidance expressed in grooming by pine voles (Microtus pinetorum): importance of context and hormonal factors. PubMed: B-complex vitamins in cultured and acidified yogurt. PubMed: Evaluation of the technological and sensory properties of durum wheat spaghetti enriched with different dietary fibres. PubMed: Antimicrobial and enzymatic antibrowning film used as coating for bamboo shoot quality improvement. PubMed: Long-term effect of ciprofloxacin on testicular tissue: evidence for biochemical and histochemical changes. PubMed: [Effects of resveratrol on morphology and oxidative stress of brain tissues in aging mice]. PubMed: Solubilization of octane in electrostatically-formed surfactant-polymer complexes. PubMed: Recent development of chitosan-based polyelectrolyte complexes with natural polysaccharides for drug delivery. PubMed: A review of the preparation and application of flavour and essential oils microcapsules based on complex coacervation technology. PubMed: Grape seed extract effects in brain after hypobaric hypoxia. PubMed: Potato protein isolates: recovery and characterization of their properties. PubMed: Marrow mesenchymal stromal cells reduce methicillin-resistant Staphylococcus aureus infection in rat models. PubMed: Controlled root targeted delivery of fertilizer using an ionically crosslinked carboxymethyl cellulose hydrogel matrix. PubMed: Novel probiotic dissolvable carboxymethyl cellulose films as oral health biotherapeutics: in vitro preparation and characterization. PubMed: Heterologous expression and biochemical characterization of an endo-β-1,4-glucanase from Thermobifida fusca. PubMed: Effect of sweeteners and hydrocolloids on quality attributes of reduced-calorie carrot juice. PubMed: Application of edible coating and acidic washing for extending the storage life of mushrooms (Agaricus bisporus). PubMed: Study of the rheological properties of a fermentation broth of the fungus Beauveria bassiana in a bioreactor under different hydrodynamic conditions. PubMed: Impact of carboxymethyl cellulose (CMC) and microcrystalline cellulose (MCC) on functional characteristics of emulsified sausages. PubMed: Structure and characteristics of acid and pepsin-solubilized collagens from the skin of cobia (Rachycentron canadum). PubMed: Biodegradation of PVP-CMC hydrogel film: A useful food packaging material. PubMed: Rectal taurocholate increases L cell and insulin secretion, and decreases blood glucose and food intake in obese type 2 diabetic volunteers. PubMed: Food-drug interactions: effect of capsaicin on the pharmacokinetics of galantamine in rats. PubMed: Chitosan, the marine functional food, is a potent adsorbent of humic acid. PubMed: Comparison of in vitro methods of measuring mucoadhesion: ellipsometry, tensile strength and rheological measurements. PubMed: Biosynthesis, purification and characterization of endoglucanase from a xylanase producing strain Aspergillus niger B03. PubMed: Influence of stabilizers on quality of sandesh from buffalo milk. PubMed: Effect of alternating magnetic field treatments on enzymatic parameters of cellulase. PubMed: Enhanced survival of probiotic Lactobacillus acidophilus by encapsulation with nanostructured polyelectrolyte layers through layer-by-layer approach. PubMed: Biodegradation of polyether-polyol-based polyurethane elastomeric films: influence of partial replacement of polyether polyol by biopolymers of renewable origin. PubMed: [Effects of resveratrol on lipid metabolism in C57BL/6J mice]. PubMed: Effectiveness of edible coatings combined with mild heat shocks on microbial spoilage and sensory quality of fresh cut broccoli (Brassica oleracea L.). PubMed: Carboxymethyl cellulose coating and low-dose gamma irradiation improves storage quality and shelf life of pear (Pyrus communis L., Cv. Bartlett/William). PubMed: Fat replacers in low-fat carboxymethyl cellulose dairy beverages: Color, rheology, and consumer perception. PubMed: Effect of carboxymethyl cellulose concentration on physical properties of biodegradable cassava starch-based films. PubMed: Acute and sub-chronic toxicity study of standardized extract of Fumaria indica in rodents. PubMed: Evaluation of certain food additives and contaminants. PubMed: Antidiabetic potential of α-amylase inhibitor from the seeds of Macrotyloma uniflorum in streptozotocin-nicotinamide-induced diabetic mice. PubMed: Physical properties of edible emulsified films based on carboxymethyl cellulose and oleic acid. PubMed: Acute toxicity and mutagenesis of three metabolites mixture of nitrobenzene in mice. PubMed: Purification and characterization of novel glucanases from Trichoderma harzianum ETS 323. PubMed: Isolation of cellulase-producing bacteria and characterization of the cellulase from the isolated bacterium Cellulomonas sp. YJ5. PubMed: In situ modification of bacterial cellulose network structure by adding interfering substances during fermentation. PubMed: Targeted discovery of glycoside hydrolases from a switchgrass-adapted compost community. PubMed: Permeability of edible coatings. PubMed: Physicochemical properties of starch-CMC-nanoclay biodegradable films. PubMed: Immobilization of mercury in sediment using stabilized iron sulfide nanoparticles. PubMed: Cellulase production from Pseudoalteromonas sp. NO3 isolated from the sea squirt Halocynthia rorentzi. PubMed: Oral administration of curcumin emulsified in carboxymethyl cellulose has a potent anti-inflammatory effect in the IL-10 gene-deficient mouse model of IBD. PubMed: Preparation of nata de coco-based carboxymethylcellulose coating and its effect on the post-harvest life of bell pepper (Capsicum annuum l.) fruits. PubMed: Disintegration of highly soluble immediate release tablets: a surrogate for dissolution. PubMed: Endoxanthanase, a novel beta-D-glucanase hydrolyzing backbone linkage of intact xanthan from newly isolated Microbacterium sp. XT11. PubMed: Chemical composition and bioactivity changes in stale rice after fermentation with Cordyceps sinensis. PubMed: Influence of additives on adhesion of Penicillium frequentans conidia to peach fruit surfaces and relationship to the biocontrol of brown rot caused by Monilinia laxa. PubMed: Antihyperglycemic effect of Cephalotaxus sinensis leaves and GLUT-4 translocation facilitating activity of its flavonoid constituents. PubMed: Inhibition by dietary hydroquinone of acetylaminofluorene induction of initiation of rat liver carcinogenesis. PubMed: Purification, characterization, and gene cloning of a chitosanase from Bacillus species strain s65. PubMed: Experimental evaluation of cyadox phototoxicity to Balb/c mouse skin. PubMed: Adsorption and conformation of carboxymethyl cellulose at solid-liquid interfaces using spectroscopic, AFM and allied techniques. PubMed: Entrapment of some compounds into biocompatible nano-sized particles and their releasing properties. PubMed: Volatile flavor analysis and sensory evaluation of custard desserts varying in type and concentration of carboxymethyl cellulose. PubMed: Molecular characterisation and developmental expression of a cellulose-binding protein gene in the soybean cyst nematode Heterodera glycines. PubMed: Interactions between meat proteins and barley (Hordeum spp.) β-glucan within a reduced-fat breakfast sausage system. PubMed: Influence of acidic beverage (Coca-Cola) on pharmacokinetics of ibuprofen in healthy rabbits. PubMed: Primate insular/opercular taste cortex: neuronal representations of the viscosity, fat texture, grittiness, temperature, and taste of foods. PubMed: Preventive effect of sialylglycopeptide-nondigestive polysaccharide conjugates on salmonella infection. PubMed: Orbitofrontal cortex: neuronal representation of oral temperature and capsaicin in addition to taste and texture. PubMed: Representation in the human brain of food texture and oral fat. PubMed: Lipase-catalyzed cellulose acetylation in aqueous and organic media. PubMed: Hydrogel network entrapping cholesterol oxidase and octadecylsilica for optical biosensing in hydrophobic organic or aqueous micelle solvents. PubMed: Effect of sodium citrate, carboxymethyl cellulose and carrageenan levels on quality characteristics of low-salt and low-fat bologna type sausages. PubMed: Evaluation of certain food additives. Fifty-ninth report of the Joint FAO/WHO Expert Committee on Food Additives. PubMed: Effect of biopolymers on structure and ice recrystallization in dynamically frozen ice cream model systems. PubMed: Plaque assay for avian metapneumovirus using a Japanese quail fibrosarcoma cell line (QT-35). PubMed: [Edible coating effects on the sensory quality of green bell pepper fruits (Capsicum annuum L.) during storage]. PubMed: Biochemical characterization and mode of action of a thermostable endoglucanase purified from Thermoascus aurantiacus. PubMed: Comparative degradation of oomycete, ascomycete, and basidiomycete cell walls by mycoparasitic and biocontrol fungi. PubMed: Investigating potential anxiolytic, antidepressant and memory enhancing activity of deprenyl. PubMed: Immunopotentiation of a developed Salmonella enterica serotype enteritidis vaccine by thymulin and zinc in meat chicken breeders. PubMed: In vitro study of possible role of dietary fiber in lowering postprandial serum glucose. PubMed: Synergistic hydrolysis of carboxymethyl cellulose and acid-swollen cellulose by two endoglucanases (CelZ and CelY) from Erwinia chrysanthemi. PubMed: Evaluation of certain food additives. Fifty-first report of the Joint FAO/WHO Expert Committee on Food Additives. PubMed: Isolation of immunoglobulin from egg yolk by anionic polysaccharides. PubMed: Properties of chitosanase from Bacillus cereus S1. PubMed: Intestinal absorption of luteolin and luteolin 7-O-beta-glucoside in rats and humans. PubMed: Biochemical studies on proteins from cheese whey and blood plasma by-products. PubMed: Low-fat papadams from black gram-tapioca blends. PubMed: Study on the developmental toxicity of orally administered isobutylidenediurea in rats. PubMed: The Effect of Xyloglucans on the Degradation of Cell-Wall-Embedded Cellulose by the Combined Action of Cellobiohydrolase and Endoglucanases from Trichoderma viride. PubMed: Heterologous expression of endo-beta-1,4-D-glucanase from Clostridium cellulovorans in Clostridium acetobutylicum ATCC 824 following transformation of the engB gene. PubMed: Enrichment of macaroni with cellulose-derivative protein complex from whey and corn steep liquor. PubMed: Effect of tumor burden and route of administration on the immunotherapeutic properties of polyinosinic-polycytidylic acid stabilized with poly-L-lysine in carboxymethyl cellulose [Poly(I,C)-LC]. PubMed: Cloning of an endo-1,4-beta-D-glucanase gene from Clostridium josui and its expression in Escherichia coli. PubMed: Inhibition of lipolytic activity in milk by polysaccharides. PubMed: Properties of Cytophaga johnsonae strains causing spoilage of fresh produce at food markets. PubMed: On talc translocation from the vagina to the oviducts and beyond. PubMed: Plasmodium gallinaceum: erythrocyte factor essential for zygote infection of Aedes aegypti. PubMed: Structural homology of storage proteins coded by the Hor-1 locus of barley (Hordeum vulgare L.). PubMed: B-complex vitamins in cultured and acidified yogurt. PubMed: Cellulolytic bacteria associated with sloughing spoilage of California ripe olives. PubMed: Multiple molecular forms of ficin-evidence against autolysis as explanation.