Identification

Namemethyl isobutyrate
IUPACmethyl 2-methylpropanoate
CAS Number547-63-7
EINECS208-929-5
FDA UNIIEM286QL922
Molecular FormulaC5 H10 O2
Molecular Weight102.13310000
MDL NumberMFCD00008914
Nikkaji NumberJ24.699I
Beilstein1740720
CoE Number287

Regulatory

JECFA Food Flavoring185 methyl isobutyrate
DG SANTE Food Flavourings09.412 methyl isobutyrate
FEMA Number2694
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)547-63-7 ; METHYL ISOBUTYRATE
FDA RegulationFDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION

Physical Properties

Appearance colorless clear liquid (est)
Assay 99.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 0.88900 to 0.89300 @ 20.00 °C.
Pounds per Gallon - (est). 7.406 to 7.439
Refractive Index 1.38200 to 1.38500 @ 20.00 °C.
Melting Point -85.00 to -84.00 °C. @ 760.00 mm Hg
Boiling Point 91.00 to 93.00 °C. @ 760.00 mm Hg, 38.00 to 39.00 °C. @ 100.00 mm Hg
Acid Value 1.00 max. KOH/g
Vapor Pressure 50.410000 mmHg @ 25.00 °C. (est)
Vapor Density 3.5 ( Air = 1 )
Flash Point 38.00 °F. TCC ( 3.33 °C. )
logP (o/w) 1.139 (est)
Soluble in alcohol
Insoluble in water

Organoleptic Properties

Odor Description
at 10.00 % in dipropylene glycol.
Etherial, diffusive, fruity, sweet and tutti-frutti
Fruity, Floral
Taste Description at 35.00 ppm.

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Oral/Parenteral Toxicityoral-rat LD50 16000 mg/kg
Dermal ToxicityNot determined
Inhalation Toxicityinhalation-mouse LC50 25500 mg/m3/2H

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavor and fragrance agents
RIFM Fragrance Material Safety AssessmentSearch
Recommendation for methyl isobutyrate usage levels up to1.0000 % in the fragrance concentrate.
Maximised Survey-derived Daily Intakes (MSDI-EU)20.00 (μg/capita/day)
baked goods48.00000
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum-
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy-
fruit ices-
gelatins / puddings-
granulated sugar-
gravies-
hard candy48.00000
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

Advanced Biotech. Inc.

Inspired by Nature

A diverse range of products, all meeting our stringent commitment to quality.

View All Website 973-339-6242 info@adv-bio.com

Alfrebro LLC/ Archer Daniels Midland Company

Let's get reacquainted

Building great taste with aroma chemicals, extracts, and distillates

View All Website 513-539-7373 sforbis@alfrebro.com

Berje Inc.

Where the world comes to its senses

Where the world comes to its senses - Berjé is a global distributor of Essential Oils and Aromatic Chemicals.

View All Website 973-748-8980 tlauzurica@berjeinc.com

Charkit Chemical Corporation

The Specialty Chemical Specialists

Explore this website to discover the products and services that Charkit provides for your industry and please contact us directly to find out how we can be of service to you.

View All Website 203-299-3220 sales@charkit.com

Fleurchem, Inc.

Have A Flavorful Day

A leading global manufacturer and supplier of ingredients for Flavors, Fragrances, AromaTherapy, Foods, Beverages, Personal Care Products, and other uses.

View All Website 845-341-2100 info@fleurchem.com

H. Interdonati, Inc.

Innovative products

Because your flavors and fragrances are only as good as their source "Since 1952"

View All Website 800 367-6617 flavorplus@hinterdonati.com

Lluch Essence S.L.

A family company dedicated to sales and distribution

Flexibility, availability, price and quality.

View All Website 34 93 379 38 49 web@lluche.com

M&U International LLC

Steady supply & demand

Meeting customers increasing demands at home as well as abroad.

View All Website 908-359-9000 sales@mu-intel.com

Penta International Corporation

Chemistry innovation

At Penta, our products and services help businesses do business better.

View All Website (973) 740-2300 lisaa@pentamfg.com

Sigma-Aldrich

Complete Supply Chain

The perfect blend of products and services that bring your creativity to life.

View All Website 800-244-1173 ff@sial.com

SRS Aromatics Ltd

For over 25 years

Bringing flavour and fragrance into your world.

View All Website +44 (0) 1284 704076 info@srsaromatics.co.uk

Sunaux International

Buy With Confidence

We have industry leading processes and procedures to ensure nothing but the most reliable product.

View All Website 0512-57995626 johnjft@sunaux.com

Synerzine, Inc.

Innovation. Customization. Aroma Ingredients.

Synerzine is a leading supplier of flavor and fragrance ingredients.

View All Website (404) 524-6744 info@synerzine.com

Taytonn ASCC Pte Ltd

Supplying Asia Pacific

We fully understand the demands of the F&F industry and we endeavour to supply quality products, with ready availability and a personalised service.

View All Website + 65 - 6861 8113 info@taytonnascc.com

TCI AMERICA

Moving Your Chemistry Forward

We continuously strive to advance our technology.

View All Website 1-800-423-8616 Sales-US@TCIchemicals.com;

R C Treatt and Co Ltd

Innovative ingredient solutions

World-leading innovative ingredient solutions provider for the flavour, fragrance and FMCG industries.

View All Website +1 863 668 9500 enquiries@treatt.com

Qingdao Free Trade Zone United International Co Ltd

Quality Products

A partner in your supply chain solution.

View All Website +86-532-83893699 info@unitedint.com

Potential Uses

FR apple FR apricot FR banana FR date FR fruit juicy fruit FR grape FR kiwi FR peach FR pear FR pineapple FR strawberry FR wine

Natural Occurrence

apple juice PMC banana fruit blueberry fruit champaca concrete @ trace% Data dill herb grape kiwi fruit kumquat peel oil melon PMC michelia alba flower absolute @ 0.50% Data naranjilla fruit papaya fruit pineapple fruit potato fried potato star fruit fruit strawberry juice

Synonyms

iso butyric acid methyl ester iso butyric acid, methyl ester methyl 2-methyl propanoate methyl 2-methyl propionate methyl 2-methylpropanoate methyl 2-methylpropionate methyl iso butyrate methyl isobutanoate nat. methyl isobutyrate methyl isobutyrate natural 2- methyl propanoic acid methyl ester methyl-iso-butyrate methylisobutyrate 2- methylpropanoic acid methyl ester propanoic acid, 2-hydroxy-, methyl ester, (±)- propanoic acid, 2-methyl-, methyl ester Info: Volatile Flavor Components in Bogyojosaeng and Suhong Cultivars of Strawberry (Fragaria ananassa Duch.) PubMed: Glass-forming properties of 3-methylbutane-1,2,3-tricarboxylic acid and its mixtures with water and pinonic acid. PubMed: Theoretical and kinetic study of the hydrogen atom abstraction reactions of esters with H(O.)2 radicals. PubMed: Fragrance material review on (4-methoxyphenyl)methyl isobutyrate. PubMed: Reaction rate coefficients of OH radicals and Cl atoms with ethyl propanoate, n-propyl propanoate, methyl 2-methylpropanoate, and ethyl n-butanoate. PubMed: Joint experimental and theoretical studies of the mechanism for the gas phase elimination kinetics of methyl 2,2-dimethyl-3-hydroxypropionate. PubMed: Palladium-catalyzed alpha-arylation of esters with chloroarenes. PubMed: Laser flash photolysis and CIDNP studies of steric effects on coupling rate constants of imidazolidine nitroxide with carbon-centered radicals, methyl isobutyrate-2-yl and tert-butyl propionate-2-yl. PubMed: NMR spectroscopy and MALDI-TOF MS characterisation of end-functionalised PVP oligomers prepared with different esters as chain transfer agents. PubMed: Palladium-catalyzed alpha-arylation of esters and amides under more neutral conditions. PubMed: Parallel synthesis: a new approach for developing analytical internal standards. Application to the analysis of patulin by gas chromatography-mass spectrometry. PubMed: Enantioselective catalysis in water: Mukaiyama-aldol condensation promoted by copper complexes of bisoxazolines supported on poly(ethylene glycol). PubMed: End-functionalised 1-vinyl-2-pyrrolidinone oligomers bearing lactate functions at one end. PubMed: DFT study of the effect of sigma-ligands on the structure of ester enolates in THF, as models of the active center in the anionic polymerization of methyl methacrylate. PubMed: Comparison of chemical analysis of residual monomer in a chemical-cured dental acrylic material to an FTIR method. PubMed: Larval osmeterial secretions of the swallowtails (Papilio). PubMed: Studies on lankacidin-group (T-2636) antibiotics. X. Microbial conversion of lankacidin-group antibiotics.