sodium orotate

4-pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-, sodium salt, (1:1)

CAS: 154-85-8 C5 H3 N2 Na O4 MW: 178.07947928

All Ingredients Aromatic Ingredients CAS Numbers EINECS Numbers Food Additives - Direct M.W Index

Identification

Name	sodium orotate
IUPAC	sodium 2,4-dioxo-1H-pyrimidine-6-carboxylate
CAS Number	154-85-8
EINECS	205-834-0
FDA UNII	1K54797G2Z
Molecular Formula	C5 H3 N2 Na O4
Molecular Weight	178.07947928
MDL Number	MFCD00050920

Regulatory

Physical Properties

Assay	95.00 to 100.00
Food Chemicals Codex Listed	No
Flash Point	32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w)	-0.928 (est)
Soluble in	water, 3.504e+004 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Preferred SDS	View
Oral/Parenteral Toxicity	Not determined
Dermal Toxicity	Not determined
Inhalation Toxicity	Not determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Category	nutrient supplements, EFSA concludes: use is of safety concern.
Recommendation for sodium orotate usage levels up to	not for fragrance use.
Recommendation for sodium orotate flavor usage levels up to	not for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

orotic acid sodium salt orotic acid, monosodium salt orotic acid, sodium salt 4- pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-, sodium salt (1:1) 4- pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-, sodium salt, (1:1) sodium 1,2,3,6-tetrahydro-2,6-dioxopyrimidine-4-carboxylate sodium 2,4-dioxo-1H-pyrimidine-6-carboxylate sodium 2,6-dihydroxypyrimidine-4-carboxylate sodium 2,6-dioxo-1,2,3,6-tetrahydro-4-pyrimidinecarboxylate sodium 2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylate mono sodium orolate PubMed: Urinary excretion of purines in sheep with experimental orotic aciduria. PubMed: Orotic acid sodium salt in kidney stones and urinary deposits. PubMed: [Electron microscopic and morphometric studies on the in vitro differentiation of mitochondria in neurons of hippocampus explant cultures as affected by orotic acid and sodium orotate]. PubMed: [The effect of orotic acid and sodium orotate on organ cultures of the hippocampus of embryonic rats]. PubMed: [The effect of active substances on nerve fiber regeneration in nerve tissue cultures]. PubMed: Effects of orotic acid and pirazetam on cortical bioelectrical activity in rabbits. PubMed: [The effect of orotic acid and orotic acid derivatives on the in vitro differentiation of hippocampus neurons-morphometric and electron microscopic studies of ribosomes].