chromium nicotinate
3-pyridinecarboxylic acid, chromium(2+) salt (2:1)
Identification
| Name | chromium nicotinate |
| IUPAC | chromium(2+); pyridine-3-carboxylate |
| CAS Number | 148485-19-9 |
| FDA UNII | Search |
| Molecular Formula | C12 H8 Cr N2 O4 |
| Molecular Weight | 296.20266000 |
| Nikkaji Number | J2.877.404D |
Regulatory
Physical Properties
| Appearance | grey-purple powder (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 292.00 to 293.00 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure | 0.000836 mmHg @ 25.00 °C. (est) |
| Flash Point | 267.00 °F. TCC ( 130.70 °C. ) (est) |
| logP (o/w) | 0.147 (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | nutrient supplements, EFSA concludes: use is of safety concern. |
| Recommendation for chromium nicotinate usage levels up to | not for fragrance use. |
| Recommendation for chromium nicotinate flavor usage levels up to | not for flavor use. |
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Exchange of knowledge
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Potential Uses
Natural Occurrence
Synonyms
chromium dinicotinate
chromium polynicotinate
chromium(2+) dinicotinate
chromium(2+); pyridine-3-carboxylate
3-
pyridinecarboxylic acid, chromium(2+) salt (2:1)
PubMed:
Organoselenium Small Molecules and Chromium(III) Complexes for Intervention in Chronic Low-grade Inflammation and Type 2 Diabetes.
PubMed:
Hypoglycemic activity and acute oral toxicity of chromium methionine complexes in mice.
PubMed:
Chromium nicotinate has no effect on insulin sensitivity, glycemic control, and lipid profile in subjects with type 2 diabetes.
PubMed:
In patients with HIV-infection, chromium supplementation improves insulin resistance and other metabolic abnormalities: a randomized, double-blind, placebo controlled trial.
PubMed:
Mass spectrometric and spectroscopic studies of the nutritional supplement chromium(III) nicotinate.
PubMed:
Nutrigenomic basis of beneficial effects of chromium(III) on obesity and diabetes.
PubMed:
HUM5007, a novel combination of thermogenic compounds, and 3-acetyl-7-oxo-dehydroepiandrosterone: each increases the resting metabolic rate of overweight adults.
PubMed:
Alteration of body composition in rats: effect of organic chromium and L-carnitine.
PubMed:
Effects of chromium nicotinate on performance, carcase characteristics and blood chemistry of growing turkeys.
PubMed:
Comparative induction of oxidative stress in cultured J774A.1 macrophage cells by chromium picolinate and chromium nicotinate.
PubMed:
Chromium and exercise training: effect on obese women.
PubMed:
Effects of different chromium compounds on blood pressure and lipid peroxidation in spontaneously hypertensive rats.
PubMed:
Chromium(III) picolinate produces chromosome damage in Chinese hamster ovary cells.
PubMed:
Effects of chromium and guar on sugar-induced hypertension in rats.
PubMed:
Chromium picolinate increases membrane fluidity and rate of insulin internalization.