cobamamide

vitamin B12 coenzyme

CAS: 13870-90-1 C72 H100 Co N18 O17 P MW: 1579.60835700

Identification

Namecobamamide
IUPAC(2S,3S,4R)-2-(6-aminopurin-9-yl)-5-methanidyloxolane-3,4-diol;cobalt(3+);[(2R,5S)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]1-[3-
CAS Number13870-90-1
EINECS237-627-6
FDA UNIIF0R1QK73KB
Molecular FormulaC72 H100 Co N18 O17 P
Molecular Weight1579.60835700
MDL NumberMFCD00135609
Beilstein4122932

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesantioxidants

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityintravenous-mouse LD50 1000 mg/kg
Dermal Toxicitysubcutaneous-mouse LD50 2000 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynutrient supplements
Recommendation for cobamamide usage levels up tonot for fragrance use.
Recommendation for cobamamide flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

found in nature

Synonyms

adenosyl cobalamin adenosylcobalamin calomide cobalamine coenzyme cobamamidum cobamide cobinamide, O-(5'-deoxyadenosine-5') deriv., hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-alpha-D-ribofuranosylbenzimidazol coenzyme B12 DBC coenzyme 5- deoxyadenosyl cobalamin 5'- deoxyadenosyl vitamin B12 deoxyadenosylcobalamin 5- deoxyadenosylcobalamin desoxy-5'-adenosine-5'alpha-(dimethyl-5,6-benzimidazolyl)cobamide dibencozide 5,6- dimethylbenzimidazolylcobamid coenzym funacomide vitamin B12 coenzyme PubMed: Dynamic, electrostatic model for the generation and control of high-energy radical intermediates by a coenzyme B₁₂-dependent enzyme. PubMed: Quantification of cyproheptadine in human plasma by high-performance liquid chromatography coupled to electrospray tandem mass spectrometry in a bioequivalence study. PubMed: The complete coenzyme B12 biosynthesis gene cluster of Lactobacillus reuteri CRL1098. PubMed: Prevention of homocysteine thiolactone induced atherogenesis in rats. PubMed: Determination of vitamin B12 using the enzyme glycerol dehydrase. PubMed: Efficacy of nutritional supplements used by athletes. PubMed: Commercially marketed supplements for bodybuilding athletes. PubMed: [Effects of carnitine and cobamamide on the dynamics of mental work capacity in patients with anorexia nervosa]. PubMed: Vitamin B12 metabolism in a photosynthesizing green alga, Chlamydomonas reinhardtii.