cobamamide
vitamin B12 coenzyme
Identification
| Name | cobamamide |
| IUPAC | (2S,3S,4R)-2-(6-aminopurin-9-yl)-5-methanidyloxolane-3,4-diol;cobalt(3+);[(2R,5S)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]1-[3- |
| CAS Number | 13870-90-1 |
| EINECS | 237-627-6 |
| FDA UNII | F0R1QK73KB |
| Molecular Formula | C72 H100 Co N18 O17 P |
| Molecular Weight | 1579.60835700 |
| MDL Number | MFCD00135609 |
| Beilstein | 4122932 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | antioxidants |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | intravenous-mouse LD50 1000 mg/kg |
| Dermal Toxicity | subcutaneous-mouse LD50 2000 mg/kg |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | nutrient supplements |
| Recommendation for cobamamide usage levels up to | not for fragrance use. |
| Recommendation for cobamamide flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
adenosyl cobalamin
adenosylcobalamin
calomide
cobalamine coenzyme
cobamamidum
cobamide
cobinamide, O-(5'-deoxyadenosine-5') deriv., hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-alpha-D-ribofuranosylbenzimidazol
coenzyme B12
DBC coenzyme
5-
deoxyadenosyl cobalamin
5'-
deoxyadenosyl vitamin B12
deoxyadenosylcobalamin
5-
deoxyadenosylcobalamin
desoxy-5'-adenosine-5'alpha-(dimethyl-5,6-benzimidazolyl)cobamide
dibencozide
5,6-
dimethylbenzimidazolylcobamid coenzym
funacomide
vitamin B12 coenzyme
PubMed:
Dynamic, electrostatic model for the generation and control of high-energy radical intermediates by a coenzyme Bââ-dependent enzyme.
PubMed:
Quantification of cyproheptadine in human plasma by high-performance liquid chromatography coupled to electrospray tandem mass spectrometry in a bioequivalence study.
PubMed:
The complete coenzyme B12 biosynthesis gene cluster of Lactobacillus reuteri CRL1098.
PubMed:
Prevention of homocysteine thiolactone induced atherogenesis in rats.
PubMed:
Determination of vitamin B12 using the enzyme glycerol dehydrase.
PubMed:
Efficacy of nutritional supplements used by athletes.
PubMed:
Commercially marketed supplements for bodybuilding athletes.
PubMed:
[Effects of carnitine and cobamamide on the dynamics of mental work capacity in patients with anorexia nervosa].
PubMed:
Vitamin B12 metabolism in a photosynthesizing green alga, Chlamydomonas reinhardtii.