delta-tocopherol
D-vitamin E
Identification
| Name | delta-tocopherol |
| IUPAC | (2R)-2,8-dimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-ol |
| CAS Number | 119-13-1 |
| FDA UNII | JU84X1II0N |
| Molecular Formula | C27 H46 O2 |
| Molecular Weight | 402.66202000 |
| MDL Number | MFCD20486794 |
| Nikkaji Number | J5.309K |
| Beilstein | 92691 |
Regulatory
| FDA/DG SANTE Petitions, Reviews, Notices | EU SANCO |
| DG SANTE Food Additives | delta-tocopherol |
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 504.00 to 505.00 °C. @ 760.00 mm Hg (est) |
| Flash Point | 392.00 °F. TCC ( 200.10 °C. ) (est) |
| logP (o/w) | 10.493 (est) |
| Soluble in | alcohol |
| Insoluble in | water |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | antioxidants |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | nutrient supplements, antioxidants |
| Recommendation for delta-tocopherol usage levels up to | not for fragrance use. |
| Recommendation for delta-tocopherol flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
2H-1-
benzopyran-6-ol, 3,4-dihydro-2,8-dimethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-, (2R)-
2H-1-
benzopyran-6-ol, 3,4-dihydro-2,8-dimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-, (2R)-
(2R(2R*(4R*,8R*)))-3,4-
dihydro-2,8-dimethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol
[2R[2R*(4R*,8R*)]]-3,4-
dihydro-2,8-dimethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol
(2R)-3,4-
dihydro-2,8-dimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol
(2R)-2,8-
dimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-ol
(2R)-2,8-
dimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-ol
(2R)-2,8-
dimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]chroman-6-ol
(+)-d-
tocopherol
(2R,4'R,8'R)-d-
tocopherol
(R,R,R)-d-
tocopherol
d-D-
tocopherol
D-
vitamin E
PubMed:
Final report on the safety assessment of Tocopherol, Tocopheryl Acetate, Tocopheryl Linoleate, Tocopheryl Linoleate/Oleate, Tocopheryl Nicotinate, Tocopheryl Succinate, Dioleyl Tocopheryl Methylsilanol, Potassium Ascorbyl Tocopheryl Phosphate, and Tocophersolan.
PubMed:
Nutritional value, chemical composition, antioxidant activity and enrichment of cream cheese with chestnut mushroom Agrocybe aegerita (Brig.) Sing.
PubMed:
Beneficial Effects of Ethanolic and Hexanic Rice Bran Extract on Mitochondrial Function in PC12 Cells and the Search for Bioactive Components.
PubMed:
Analysis of vitamin E metabolites including carboxychromanols and sulfated derivatives using liquid chromatography tandem mass spectrometry.
PubMed:
Tocopherols in Sunflower Seedlings under Light and Dark Conditions.
PubMed:
Wine grape pomace flour improves blood pressure, fasting glucose and protein damage in humans: a randomized controlled trial.
PubMed:
Determination of tocopherols and sitosterols in seeds and nuts by QuEChERS-liquid chromatography.
PubMed:
Effects of omega-3 PUFA on the vitamin E and glutathione antioxidant defense system in individuals at ultra-high risk of psychosis.
PubMed:
Short communication: Effect of conjugated linoleic acid on concentrations of fat-soluble vitamins in milk of lactating ewes.
PubMed:
Tocopherols and tocotrienols in serum and liver of dairy cows receiving conjugated linoleic acids or a control fat supplement during early lactation.
PubMed:
Vitamin E: Curse or Benefit in Alzheimer's Disease? A Systematic Investigation of the Impact of α-, γ- and δ-Tocopherol on Aà Generation and Degradation in Neuroblastoma Cells.
PubMed:
Dietary, supplement, and adipose tissue tocopherol levels in relation to prostate cancer aggressiveness among African and European Americans: The North Carolina-Louisiana Prostate Cancer Project (PCaP).
PubMed:
Characteristics of rose hip (Rosa canina L.) cold-pressed oil and its oxidative stability studied by the differential scanning calorimetry method.
PubMed:
γ-Tocotrienol reduces human airway smooth muscle cell proliferation and migration.
PubMed:
A new 9,10-dihydrophenanthrene and cell proliferative 3,4-δ-dehydrotocopherols from Stemona tuberosa.
PubMed:
Singlet oxygen autoxidation of vegetable oils: evidences for lack of synergy between β-carotene and tocopherols.
PubMed:
δ-Tocopherol prevents methylglyoxal-induced apoptosis by reducing ROS generation and inhibiting apoptotic signaling cascades in human umbilical vein endothelial cells.
PubMed:
Post-synthetic modification of MIL-101(Cr) with pyridine for high-performance liquid chromatographic separation of tocopherols.
PubMed:
Serum tocopherol levels and vitamin E intake are associated with lung function in the normative aging study.
PubMed:
Antioxidant activities of tocopherols/tocotrienols and lipophilic antioxidant capacity of wheat, vegetable oils, milk and milk cream by using photochemiluminescence.
PubMed:
Tocochromanols composition in kernels recovered from different apricot varieties: RP-HPLC/FLD and RP-UPLC-ESI/MS(n) study.
PubMed:
Regenerable antioxidants-introduction of chalcogen substituents into tocopherols.
PubMed:
A correlation between tocopherol content and antioxidant activity in seeds and germinating seeds of soybean cultivars.
PubMed:
Comparison of the physico-chemical and phytochemical characteristics of the oil of two Plukenetia species.
PubMed:
Influence of deficit irrigation strategies on fatty acid and tocopherol concentration of almond (Prunus dulcis).
PubMed:
Vitamin E isomer δ-tocopherol enhances the efficiency of neural stem cell differentiation via L-type calcium channel.
PubMed:
Tocochromanols and carotenoids in sorghum (Sorghum bicolor L.): diversity and stability to the heat treatment.
PubMed:
Unique variability of tocopherol composition in various seed oils recovered from by-products of apple industry: rapid and simple determination of all four homologues (α, β, γ and δ) by RP-HPLC/FLD.
PubMed:
Pharmacological potential of tocotrienols: a review.
PubMed:
Potent inhibitory effect of δ-tocopherol on prostate cancer cells cultured in vitro and grown as xenograft tumors in vivo.
PubMed:
Increased antioxidant efficacy of tocopherols by surfactant solubilization in oil-in-water emulsions.
PubMed:
Vitamin E-drug interactions: molecular basis and clinical relevance.
PubMed:
Effects of antioxidants and additional emulsifiers on the stability of emulsified milk fat in the photo/radical oxidation system.
PubMed:
High environmental stress yields greater tocotrienol content while changing vitamin e profiles of wild emmer wheat seeds.
PubMed:
Antiradical activities and phytochemical compounds of firethorn (Pyracantha coccinea) fruit extracts.
PubMed:
Tocopherols in Seafood and Aquaculture Products.
PubMed:
Niemann-Pick Disease Type C: Induced Pluripotent Stem Cell-Derived Neuronal Cells for Modeling Neural Disease and Evaluating Drug Efficacy.
PubMed:
Vitamins, fatty acids, and antioxidant capacity stability during storage of freeze-dried human milk.
PubMed:
Plasma and dietary carotenoids and vitamins A, C and E and risk of colon and rectal cancer in the European Prospective Investigation into Cancer and Nutrition.
PubMed:
Optimization conditions of samples saponification for tocopherol analysis.
PubMed:
Natural forms of vitamin E: metabolism, antioxidant, and anti-inflammatory activities and their role in disease prevention and therapy.
PubMed:
Uptake of the cyanobacterial neurotoxin, anatoxin-a, and alterations in oxidative stress in the submerged aquatic plant Ceratophyllum demersum.
PubMed:
Fatty acid and tocopherol contents of several soybean oils.
PubMed:
Concentrations of tocols and γ-oryzanol compounds in rice bran oil obtained by fractional extraction with supercritical carbon dioxide.
PubMed:
Effect of cyclolinopeptides on the oxidative stability of flaxseed oil.
PubMed:
Catalytic antioxidants: regenerable tellurium analogues of vitamin E.
PubMed:
Modulation of NF-κB and Nrf2 control of inflammatory responses in FHs 74 Int cell line is tocopherol isoform-specific.
PubMed:
Increases in both acute and chronic temperature potentiate tocotrienol concentrations in wild barley at 'Evolution Canyon'.
PubMed:
Gamma-tocopherol attenuates moderate but not severe colitis and suppresses moderate colitis-promoted colon tumorigenesis in mice.
PubMed:
The methanolic extract of Cordyceps militaris (L.) Link fruiting body shows antioxidant, antibacterial, antifungal and antihuman tumor cell lines properties.
PubMed:
Vitamin E secretion by Caco-2 monolayers to APOA1, but not to HDL, is vitamer selective.
PubMed:
Inhibitory effects of tocopherols on expression of the cyclooxygenase-2 gene in RAW264.7 cells stimulated by lipopolysaccharide, tumor necrosis factor-α or Porphyromonas gingivalis fimbriae.
PubMed:
High expression of tocochromanol biosynthesis genes increases the vitamin E level in a new line of giant embryo rice.
PubMed:
Low vitamin and carotenoid levels are related to cerebral white matter lesions.
PubMed:
Impact of roasting on the chemical composition and oxidative stability of perilla oil.
PubMed:
Profiles of lipid components, fatty acid distributions of triacylglycerols and phospholipids in Jack beans (Canavalia gladiata DC.).
PubMed:
δ-Tocopherol reduces lipid accumulation in Niemann-Pick type C1 and Wolman cholesterol storage disorders.
PubMed:
Comprehensive profiling of carotenoids and fat-soluble vitamins in milk from different animal species by LC-DAD-MS/MS hyphenation.
PubMed:
Dietary administration of δ- and γ-tocopherol inhibits tumorigenesis in the animal model of estrogen receptor-positive, but not HER-2 breast cancer.
PubMed:
Compositional study and antioxidant potential of Ipomoea hederacea Jacq. and Lepidium sativum L. seeds.
PubMed:
Plasma and tissue concentrations of α-tocopherol and δ-tocopherol following high dose dietary supplementation in mice.
PubMed:
Effects of electron-beam radiation on nutritional parameters of Portuguese chestnuts (Castanea sativa Mill.).
PubMed:
Notable effects of metal salts on UV-vis absorption spectra of α-, β-, γ-, and δ-tocopheroxyl radicals in acetonitrile solution. The complex formation between tocopheroxyls and metal cations.
PubMed:
Modulated phases of phospholipid bilayers induced by tocopherols.
PubMed:
Rapid method for the determination of vitamins A and E in foods using ultra-high-performance liquid chromatography.
PubMed:
Identification of plasmalogen in the gut of silkworm (Bombyx mori).
PubMed:
Rapid baseline-separation of all eight tocopherols and tocotrienols by reversed-phase liquid-chromatography with a solid-core pentafluorophenyl column and their sensitive quantification in plasma and liver.
PubMed:
Chemical characterization of chestnut cultivars from three consecutive years: chemometrics and contribution for authentication.
PubMed:
Enzymatic interesterification of palm stearin with Cinnamomum camphora seed oil to produce zero-trans medium-chain triacylglycerols-enriched plastic fat.
PubMed:
Plasma vitamin E and coenzyme Q10 are not associated with a lower risk of acute myocardial infarction in Singapore Chinese adults.
PubMed:
Production of human milk fat analogue containing docosahexaenoic and arachidonic acids.
PubMed:
Vitamins at physiological levels cause oxidation to the DNA nucleoside deoxyguanosine and to DNA--alone or in synergism with metals.
PubMed:
Impact of high-pressure processing on vitamin E (α-, γ-, and δ-tocopherol), vitamin D (cholecalciferol and ergocalciferol), and fatty acid profiles in liquid foods.
PubMed:
Antioxidant capacities of phenolic compounds and tocopherols from Tunisian pomegranate (Punica granatum) fruits.
PubMed:
Soybean (Glycine max) oil bodies and their associated phytochemicals.
PubMed:
δ- and γ-tocopherols, but not α-tocopherol, inhibit colon carcinogenesis in azoxymethane-treated F344 rats.
PubMed:
Fatty acid, cholesterol and fat-soluble vitamin composition of wild and captive freshwater crayfish (Astacus leptodactylus).
PubMed:
Fatty acids, tocopherols, selenium and total carotene of pistachios (P. vera L.) from Diyarbakir (Southeastern Turkey) and walnuts (J. regia L.) from Erzincan (Eastern Turkey).
PubMed:
Antiproliferative and proapoptotic effects of tocopherol and tocol on activated hepatic stellate cells.
PubMed:
The fatty acid and tocopherol constituents of the seed oil extracted from 21 grape varieties (Vitis spp.).
PubMed:
Chemopreventive activity of vitamin E in breast cancer: a focus on γ- and δ-tocopherol.
PubMed:
Determination of tocopherol and tocotrienol content of Greek barley varieties under conventional and organic cultivation techniques using validated reverse phase high-performance liquid chromatography method.
PubMed:
Determination of lipoic acid, Trolox methyl ether and tocopherols in human plasma by liquid-chromatography and ion-trap tandem mass spectrometry.
PubMed:
In vitro fermented nuts exhibit chemopreventive effects in HT29 colon cancer cells.
PubMed:
Varying quality of fish oil capsules: fatty acids and tocopherol.
PubMed:
Effects of high temperature stress at different development stages on soybean isoflavone and tocopherol concentrations.
PubMed:
γ-Tocopherol methyltransferase from the green alga Chlamydomonas reinhardtii: functional characterization and expression analysis.
PubMed:
Expression of modified tocopherol content and profile in sunflower tissues.
PubMed:
Legumes are valuable sources of tocopherols.
PubMed:
Vitamin E prevents the age-dependent and palmitate-induced disturbances of sphingolipid turnover in liver cells.
PubMed:
Vitamin E forms inhibit IL-13/STAT6-induced eotaxin-3 secretion by up-regulation of PAR4, an endogenous inhibitor of atypical PKC in human lung epithelial cells.
PubMed:
Supercritical COâextraction of oleoresin from marigold (Tagetes erecta L.) flowers and determination of its antioxidant components with online HPLC-ABTS(·+) assay.
PubMed:
Chemical genoprotection: reducing biological damage to as low as reasonably achievable levels.
PubMed:
Tocopherol concentration in almond oil: genetic variation and environmental effects under warm conditions.
PubMed:
Characterization of medium-chain triacylglycerol (MCT)-enriched seed oil from Cinnamomum camphora (Lauraceae) and its oxidative stability.
PubMed:
δ-tocopherol is more active than α - or γ -tocopherol in inhibiting lung tumorigenesis in vivo.
PubMed:
Inhibitory Effect of a γ-Tocopherol-Rich Mixture of Tocopherols on the Formation and Growth of LNCaP Prostate Tumors in Immunodeficient Mice.
PubMed:
Evaluation of a method based on liquid chromatography-diode array detector-tandem mass spectrometry for a rapid and comprehensive characterization of the fat-soluble vitamin and carotenoid profile of selected plant foods.
PubMed:
Natural forms of vitamin E and 13'-carboxychromanol, a long-chain vitamin E metabolite, inhibit leukotriene generation from stimulated neutrophils by blocking calcium influx and suppressing 5-lipoxygenase activity, respectively.
PubMed:
The effects of fungal stress on the antioxidant contents of black soybeans under germination.
PubMed:
Distribution of α- and δ-tocopherols in seminal plasma and sperm fractions of men with normal and abnormal semen parameters.
PubMed:
Modulation of salt (NaCl)-induced effects on oil composition and fatty acid profile of sunflower (Helianthus annuus L.) by exogenous application of salicylic acid.
PubMed:
Proapoptotic effects of long-chain vitamin E metabolites in HepG2 cells are mediated by oxidative stress.
PubMed:
Characterization of a potential nutraceutical ingredient: pomegranate (Punica granatum L.) seed oil unsaponifiable fraction.
PubMed:
The comparison of black currant juice and vitamin E for the prevention of oxidative stress.
PubMed:
19F MRI of 3D CEM cells to study the effects of tocopherols and tocotrienols.
PubMed:
High plasma levels of vitamin E forms and reduced Alzheimer's disease risk in advanced age.
PubMed:
Soybean tocopherol concentrations are affected by crop management.
PubMed:
Effects of vitamin E on the osteoblast differentiation.
PubMed:
Relationships among dietary nutrients and subjective sleep, objective sleep, and napping in women.
PubMed:
Partition of tocopheryl glucopyranoside into liposome membranes studied by fluorescence methods.
PubMed:
Follicular fluid high density lipoprotein-associated micronutrient levels are associated with embryo fragmentation during IVF.
PubMed:
Xenia effects on oil content and fatty acid and tocopherol concentrations in autogamous almond cultivars.
PubMed:
Investigation of liquid wax components of Egyptian jojoba seeds.
PubMed:
Degradation of tocopherols in rice bran oil submitted to heating at different temperatures.
PubMed:
Effect of genotype, environment, and their interaction on chemical composition and antioxidant properties of low-linolenic soybeans grown in Maryland.
PubMed:
Plasma levels of retinoids, carotenoids and tocopherols in patients with mild obstructive sleep apnoea.
PubMed:
Production of beta-maltooligosaccharides of alpha- and delta-tocopherols by Klebsiella pneumoniae and cyclodextrin glucanotransferase as anti-allergic agents.
PubMed:
Comparison of plasma antioxidant levels and related metabolic parameters between smokers and non-smokers.
PubMed:
Comparison of the inhibitory effects of vitamin E analogues on melanogenesis in mouse B16 melanoma cells.
PubMed:
Inhibition of lung cancer growth in mice by dietary mixed tocopherols.
PubMed:
Assessment of variation in antioxidative defense system in salt-treated pea (Pisum sativum) cultivars and its putative use as salinity tolerance markers.
PubMed:
High tocopherol and triacylglycerol contents in Pinus pinea L. seeds.
PubMed:
The application of 19F magnetic resonance ex vivo imaging of three-dimensional cultured breast cancer cells to study the effect of delta-tocopherol.
PubMed:
Alpha-, gamma- and delta-tocopherols reduce inflammatory angiogenesis in human microvascular endothelial cells.
PubMed:
Protection of half sulfur mustard gas-induced lung injury in guinea pigs by antioxidant liposomes.
PubMed:
Identification and assessment of antioxidant capacity of phytochemicals from kiwi fruits.
PubMed:
Isocratic rapid liquid chromatographic method for simultaneous determination of carotenoids, retinol, and tocopherols in human serum.
PubMed:
Relative changes in tocopherols, isoflavones, total phenolic content, and antioxidative activity in soybean seeds at different reproductive stages.
PubMed:
Liposoluble antioxidants provide an effective radioprotective barrier.
PubMed:
Quality and lipid composition of spermatozoa in rabbits fed DHA and vitamin E rich diets.
PubMed:
Comparison between the free-radical-scavenging activities with vitamin E and ubiquinol in biological systems based on their reaction rates: a research account.
PubMed:
Screening and comparing tocopherols in the rapeseed (Brassica napus L.) and olive (Olea europaea L.) varieties using high-performance liquid chromatography.
PubMed:
Oil and fatty acid diversity in genetically variable clones of Moringa oleifera from India.
PubMed:
Long-chain carboxychromanols, metabolites of vitamin E, are potent inhibitors of cyclooxygenases.
PubMed:
Vitamin A and vitamin E isoforms stability and peroxidation potential of all-in-one admixtures for parenteral nutrition.
PubMed:
Dietary marine-derived tocopherol has a higher biological availability in mice relative to alpha-tocopherol.
PubMed:
Off-line coupling of pressurized liquid extraction and LC/ED for the determination of retinyl acetate and tocopherols in infant formulas.
PubMed:
Distribution of alpha-, gamma (+beta)- and delta-tocopherol in the seminal plasma, spermatozoa and seminal vesicles of rabbit.
PubMed:
Nanoemulsions of an anti-oxidant synergy formulation containing gamma tocopherol have enhanced bioavailability and anti-inflammatory properties.
PubMed:
Heterogeneous effects of distinct tocopherol analogues on NO release, cell volume, and cell death in microglial cells.
PubMed:
Development of saw palmetto (Serenoa repens) fruit and extract standard reference materials.
PubMed:
Inhibition of oxidative metabolism of tocopherols with omega-N-heterocyclic derivatives of vitamin E.
PubMed:
Tocopherols and tocotrienols in sea buckthorn (Hippophae rhamnoides L.) berries during ripening.
PubMed:
Comparison of nutritional traits variability in selected eighty-seven inbreds from Chinese maize (Zea mays L.) germplasm.
PubMed:
Circular dichroism of tocopherols versus tocotrienols.
PubMed:
Comparison of extraction methods for quantifying vitamin E from animal tissues.
PubMed:
Separation of alpha-, beta-, gamma-, delta-tocopherols and alpha-tocopherol acetate on a pentaerythritol diacrylate monostearate-ethylene dimethacrylate monolith by capillary electrochromatography.
PubMed:
Dietary alpha-, beta-, gamma- and delta-tocopherols in lung cancer risk.
PubMed:
Caryodendron orinocense ('nuez de Barinas') oil: tocopherol content and use in cosmetics.
PubMed:
Plasma tocopherols and risk of cognitive impairment in an elderly Italian cohort.
PubMed:
Tocotrienols, the unsaturated forms of vitamin E, can function as antioxidants and lipid protectors in tobacco leaves.
PubMed:
Genetic possibilities for altering sunflower oil quality to obtain novel oils.
PubMed:
In vivo gamma-tocopherol supplementation decreases systemic oxidative stress and cytokine responses of human monocytes in normal and asthmatic subjects.
PubMed:
Enhanced anti-proliferative effects of combinatorial treatment of delta-tocopherol and resveratrol in human HMC-1 cells.
PubMed:
Modulation of proteasome activity by vitamin E in THP-1 monocytes.
PubMed:
Kinetic studies of the free radical-scavenging actions of tocopherol metabolites (alpha-, gamma-, and delta-carboxyethyl-6-hydroxychroman) and Trolox in ethanol and micellar solutions.
PubMed:
A survey of sesamin and composition of tocopherol variability from seeds of eleven diverse sesame (Sesamum indicum L.) genotypes using HPLC-PAD-ECD.
PubMed:
Tocopherol content and isomers' composition in selected plant species.
PubMed:
Roselle (Hibiscus sabdariffa) seed oil is a rich source of gamma-tocopherol.
PubMed:
Effect of vitamin supplementation on breast milk concentrations of retinol, carotenoids and tocopherols in HIV-infected Tanzanian women.
PubMed:
Effect of type of oil and addition of delta-tocopherol on model flavor compound stability during storage.
PubMed:
Effect of total replacement of pork backfat with walnut on the nutritional profile of frankfurters.
PubMed:
Total alpha-tocopherol intakes are associated with serum alpha-tocopherol concentrations in African American adults.
PubMed:
Resveratrol (trans-3,4',5-trihydroxystilbene) decreases lipid peroxidation level and protects antioxidant capacity in sera and erythrocytes of old female Wistar rats induced by the kidney carcinogen potassium bromate.
PubMed:
Increased bioavailability of a transdermal application of a nano-sized emulsion preparation.
PubMed:
Antibacterial constituents from Stemona sessilifolia.
PubMed:
Comprehensive analysis of vitamin E constituents in human plasma by liquid chromatography-mass spectrometry.
PubMed:
Effects of tocopherols and 2,2'-carboxyethyl hydroxychromans on phorbol-ester-stimulated neutrophils.
PubMed:
Vitamin E chemistry. Nitration of non-alpha-tocopherols: products and mechanistic considerations.
PubMed:
Glycosylation of tocopherols by cultured cells of Eucalyptus perriniana.
PubMed:
Gamma-tocopherol as a marker of Brazilian coffee (Coffea arabica L.) adulteration by corn.
PubMed:
Mechanism of deactivation of triplet-excited riboflavin by ascorbate, carotenoids, and tocopherols in homogeneous and heterogeneous aqueous food model systems.
PubMed:
Improved antioxidant activity of Vitamin E through solubilization in ethanol: A model study with ground beef.
PubMed:
Comparison of reversed-phase liquid chromatography-mass spectrometry with electrospray and atmospheric pressure chemical ionization for analysis of dietary tocopherols.
PubMed:
Tocotrienols in health and disease: the other half of the natural vitamin E family.
PubMed:
Identification and determination of fat-soluble vitamins and metabolites in human serum by liquid chromatography/triple quadrupole mass spectrometry with multiple reaction monitoring.
PubMed:
Oil and tocopherol content and composition of pumpkin seed oil in 12 cultivars.
PubMed:
Antioxidant content and free radical scavenging ability of fresh red pummelo [Citrus grandis (L.) Osbeck] juice and freeze-dried products.
PubMed:
Tocopherol and tocotrienol levels of foods consumed in Hawaii.
PubMed:
Structure-activity relationship of the free-radical-scavenging reaction by vitamin E (alpha-, beta-, gamma-, delta-Tocopherols) and ubiquinol-10: pH dependence of the reaction rates.
PubMed:
Bioavailability of a novel, water-soluble vitamin E formulation in malabsorbing patients.
PubMed:
Free radical interaction between vitamin E (alpha-, beta-, gamma- and delta-tocopherol), ascorbate and flavonoids.
PubMed:
A pharmacological action of vitamin E unrelated to its antioxidant capacity.
PubMed:
Associations between serum carotenoids and tocopherols and type-specific HPV persistence: the Ludwig-McGill cohort study.
PubMed:
Dietary supplementation with 11trans- and 12trans-18:1 and oxidative stress in humans.
PubMed:
Does gamma-tocopherol play a role in the primary prevention of heart disease and cancer? A review.
PubMed:
Microemulsion electrokinetic chromatography for the separation of retinol, cholecalciferol, delta-tocopherol and alpha-tocopherol.
PubMed:
Significant differences in the electrochemical behavior of the alpha-, beta-, gamma-, and delta-tocopherols (vitamin E).
PubMed:
Simultaneous analysis of Vitamins A and E in infant milk-based formulae by normal-phase high-performance liquid chromatography-diode array detection using a short narrow-bore column.
PubMed:
Esterase-activated chromane-sydnonimine prodrug hybrids.
PubMed:
Increased levels of F2-isoprostanes following aneurysmal subarachnoid hemorrhage in humans.
PubMed:
Combined lycopene and vitamin E treatment suppresses the growth of PC-346C human prostate cancer cells in nude mice.
PubMed:
Liquid chromatograpic-mass spectrometric analysis of phenolics and free radical scavenging activity of rosemary extract from different raw material.
PubMed:
Prooxidant and antioxidant activity of vitamin E analogues and troglitazone.
PubMed:
Increased expression of transglutaminase-1 and PPARgamma after vitamin E treatment in human keratinocytes.
PubMed:
Recent advances in vitamin E metabolism and deficiency.
PubMed:
Tocotrienols: Vitamin E beyond tocopherols.
PubMed:
Cyclodextrin-modified microemulsion electrokinetic chromatography for separation of alpha-, gamma-, delta-tocopherol and alpha-tocopherol acetate.
PubMed:
Induction of cytokines by radioprotective tocopherol analogs.
PubMed:
Coenzyme Q concentration and total antioxidant capacity of human milk at different stages of lactation in mothers of preterm and full-term infants.
PubMed:
Sources of variation in nutrient intakes among men in Shanghai, China.
PubMed:
Selective accumulation of alpha-tocopherol in Drosophila is associated with cytochrome P450 tocopherol-omega-hydroxylase activity but not alpha-tocopherol transfer protein.
PubMed:
Effect of temperature, cholesterol content, and antioxidant structure on the mobility of vitamin E constituents in biomembrane models studied by laterally diffusion-controlled fluorescence quenching.
PubMed:
Fat-soluble and water-soluble vitamin contents of breast milk from Japanese women.
PubMed:
Glucosinolates and fatty acid, sterol, and tocopherol composition of seed oils from Capparis spinosa Var. spinosa and Capparis ovata Desf. Var. canescens (Coss.) Heywood.
PubMed:
Slow internal release of bioactive compounds under the effect of skin enzymes.
PubMed:
[Effects of packaging on the stability of vitamin E in peach kernels stored at high temperature].
PubMed:
Vitamin E composition of walnuts (Juglans regia L.): a 3-year comparative study of different cultivars.
PubMed:
The relationship between the physicochemical properties of antioxidants and their ability to inhibit lipid oxidation in bulk oil and oil-in-water emulsions.
PubMed:
Model system for testing the efficacy of antioxidants in muscle foods.
PubMed:
Tocotrienol: the natural vitamin E to defend the nervous system?
PubMed:
Solution to spectroscopy challenge 8.
PubMed:
Effect of processing on the antioxidant vitamins and antioxidant capacity of Vigna sinensis Var. Carilla.
PubMed:
Assessment of lipid peroxidation and serum vitamin E concentration in dogs with immune-mediated hemolytic anemia.
PubMed:
gamma-Tocopherol or combinations of vitamin E forms induce cell death in human prostate cancer cells by interrupting sphingolipid synthesis.
PubMed:
The cytotoxicity of vitamin E is both vitamer- and cell-specific and involves a selectable trait.
PubMed:
Recombinant SEC14-like proteins (TAP) possess GTPase activity.
PubMed:
Skin absorption and metabolism of a new vitamin E prodrug, delta-tocopherol-glucoside: in vitro evaluation in human skin models.
PubMed:
Antioxidant dehydrotocopherols as a new chemical character of Stemona species.
PubMed:
Distribution of exogenous delta-tocopherol between the membrane lipids and triacylglycerols of a cod muscle-triacylglycerol model system.
PubMed:
Variation in nutrient intakes among women in Shanghai, China.
PubMed:
Development of a validated liquid chromatography method for the simultaneous determination of eight fat-soluble vitamins in biological fluids after solid-phase extraction.
PubMed:
Non-antioxidant activities of vitamin E.
PubMed:
A case-control study of serum tocopherol levels and the alpha- to gamma-tocopherol ratio in radiographic knee osteoarthritis: the Johnston County Osteoarthritis Project.
PubMed:
Tocopherol composition of deodorization distillates and their antioxidative activity.
PubMed:
Dietary antioxidant intake and risk of type 2 diabetes.
PubMed:
Antioxidants, carotenoids, and risk of rectal cancer.
PubMed:
Effects of alpha-, gamma-, and delta-tocopherols on the autoxidation of purified rapeseed oil triacylglycerols in a system containing low oxygen.
PubMed:
Antioxidizing potency of phenol compounds in olive oil mill wastewater.
PubMed:
Simultaneous determination of tocotrienols, tocopherols, retinol, and major carotenoids in human plasma.
PubMed:
Engineering vitamin E content: from Arabidopsis mutant to soy oil.
PubMed:
Electrophile tocopheryl quinones in apoptosis and mutagenesis: thermochemolysis of thiol adducts with proteins and in cells.
PubMed:
Antioxidant effect of gamma-tocopherol supplied by propofol preparations (Diprivan) during ischemia-reperfusion in experimental lung transplantation.
PubMed:
[Effect of apoptosis induced by different vitamin E homologous analogues in human hepatoma cells(HepG2)].
PubMed:
Dietary (+)-catechin and BHT markedly increase alpha-tocopherol concentrations in rats by a tocopherol-omega-hydroxylase-independent mechanism.
PubMed:
Supplementation of diets with alpha-tocopherol reduces serum concentrations of gamma- and delta-tocopherol in humans.
PubMed:
Serum vitamins and the subsequent risk of bladder cancer.
PubMed:
Foreign body-type multinucleated giant cell formation is potently induced by alpha-tocopherol and prevented by the diacylglycerol kinase inhibitor R59022.
PubMed:
[Effect of apoptosis induced by different vitamin E homologous analogues in human hepatoma cells (HepG2)].
PubMed:
Non-nutritive bioactive food constituents of plants: tocopherols (vitamin E).
PubMed:
Antiphoto-oxidative activity of sesamol in methylene blue- and chlorophyll-sensitized photo-oxidation of oil.
PubMed:
[Effect of different vitamin E homologous analogues on human hepatoma cell HepG2 proliferation in vitro].
PubMed:
ESR study of a biological assay on whole blood: antioxidant efficiency of various vitamins.
PubMed:
Vitamin E isoforms alpha-tocotrienol and gamma-tocopherol prevent cerebral infarction in mice.
PubMed:
Determination of tocopherols, tocopherolquinones and tocopherolhydroquinones by gas chromatography-mass spectrometry and preseparation with lipophilic gel chromatography.
PubMed:
Partitioning of exogenous delta-tocopherol between the triacylglycerol and membrane lipid fractions of chicken muscle.
PubMed:
Development and validation of a fast and sensitive chromatographic assay for all-trans-retinol and tocopherols in human serum and plasma using liquid-liquid extraction.
PubMed:
Warm temperatures or drought during seed maturation increase free alpha-tocopherol in seeds of soybean (Glycine max [L.] Merr.).
PubMed:
Mixed tocopherols have a stronger inhibitory effect on lipid peroxidation than alpha-tocopherol alone.
PubMed:
Supercritical fluid extraction of lycopene from tomato processing byproducts.
PubMed:
Development and validation of oxygen radical absorbance capacity assay for lipophilic antioxidants using randomly methylated beta-cyclodextrin as the solubility enhancer.
PubMed:
Lipid composition of some yeast strains from Livingston Island, Antarctica.
PubMed:
Does lack of tocopherols and tocotrienols put women at increased risk of breast cancer?
PubMed:
Vitamin E inhibition of normal mammary epithelial cell growth is associated with a reduction in protein kinase C(alpha) activation.
PubMed:
Relationship between fatty acid profile and vitamin E content in maize hybrids (Zea mays L.).
PubMed:
Different isoforms of tocopherols enhance nitric oxide synthase phosphorylation and inhibit human platelet aggregation and lipid peroxidation: implications in therapy with vitamin E.
PubMed:
Gas chromatographic characterization of vegetable oil deodorization distillate.
PubMed:
Tocopherols are metabolized in HepG2 cells by side chain omega-oxidation and consecutive beta-oxidation.
PubMed:
Evidence for alterations in circulating low-molecular-weight antioxidants and increased lipid peroxidation in smokers on hemodialysis.
PubMed:
Stability of thiamine and vitamins E and A during storage of enteral feeding formula.
PubMed:
Changes in antioxidative mechanisms in elderly patients with non-insulin-dependent diabetes mellitus. Investigation of the redox dynamics of alpha-tocopherol in erythrocyte membranes.
PubMed:
Different tocopherols and the relationship between two methods for determination of primary oxidation products in fish oil.
PubMed:
Comparison of the column performance of narrow-bore and standard-bore columns for the chromatographic determination of alpha-, beta-, gamma-, and delta-tocopherol.
PubMed:
Alteration of fatty acid composition, tocopherol content and peroxide value in margarine during storage at various temperatures.
PubMed:
Gamma-linolenic acid and tocopherol contents in the seed oil of 47 accessions from several Ribes species.
PubMed:
Lipophilic antioxidants and iron status in ESRD patients on hemodialysis.
PubMed:
Absorption by rats of tocopherols present in edible vegetable oils.
PubMed:
Cytochrome P4503A-dependent metabolism of tocopherols and inhibition by sesamin.
PubMed:
Relation between insulin resistance and plasma concentrations of lipid hydroperoxides, carotenoids, and tocopherols.
PubMed:
Antiproliferative and apoptotic effects of tocopherols and tocotrienols on preneoplastic and neoplastic mouse mammary epithelial cells.
PubMed:
Automated analysis of vitamin E isomers in vegetable oils by continuous membrane extraction and liquid chromatography-electrochemical detection.
PubMed:
Fatty acids and tocochromanols in seeds of Orobanche.
PubMed:
Vitamin E: non-antioxidant roles.
PubMed:
Antiproliferative and apoptotic effects of tocopherols and tocotrienols on normal mouse mammary epithelial cells.
PubMed:
Concentrations of tocopherols and carotenoids in maternal and cord blood plasma.
PubMed:
Vitamin E inhibition of O2*- production in the promonocyte cell line THP-1 is essentially due to RRR-delta-tocopherol.
PubMed:
Vitamin E: function and metabolism.
PubMed:
Induction of apoptosis in human breast cancer cells by tocopherols and tocotrienols.
PubMed:
Simultaneous determination of alpha-tocopheryl acetate and tocopherols in aquatic organisms and fish feed.
PubMed:
Prevention of DNA photodamage by vitamin E compounds and sunscreens: roles of ultraviolet absorbance and cellular uptake.
PubMed:
Value assignment of retinol, retinyl palmitate, tocopherol, and carotenoid concentrations in Standard Reference Material 2383 (Baby Food Composite).
PubMed:
Maternal and neonatal plasma antioxidant levels in normal pregnancy, and the relationship with fatty acid unsaturation.
PubMed:
Silver-plated vitamins: a method of detecting tocopherols and carotenoids in LC/ESI-MS coupling.
PubMed:
alpha- and delta-tocopherol induce expression of hepatic alpha-tocopherol-transfer-protein mRNA.
PubMed:
alpha-Tocopherol protects PC12 cells from hyperoxia-induced apoptosis.
PubMed:
Dissimilar protection of tocopherol isomers against membrane hydrolysis by phospholipase A2.
PubMed:
In vivo antioxidant activity of Okara Koji, a fermented okara, by Aspergillus oryzae.
PubMed:
Shape selectivity of C30 phases for RP-HPLC separation of tocopherol isomers and correlation with MAS NMR data from suspended stationary phases.
PubMed:
Relative stability of carotenoid radical cations and homologue tocopheroxyl radicals. A real time kinetic study of antioxidant hierarchy.
PubMed:
Inhibition of UVB induced DNA photodamage in mouse epidermis by topically applied alpha-tocopherol.
PubMed:
Serum micronutrients and prostate cancer in Japanese Americans in Hawaii.
PubMed:
Affinity for alpha-tocopherol transfer protein as a determinant of the biological activities of vitamin E analogs.
PubMed:
Certification of nutrients in Standard Reference Material 1846: infant formula.
PubMed:
High D-glucose does not affect binding of alpha-tocopherol to human erythrocytes.
PubMed:
A rapid method for the determination of vitamin E forms in tissues and diet by high-performance liquid chromatography using a normal-phase diol column.
PubMed:
Lipid peroxidation-associated oxidative stress during percutaneous transluminal coronary angioplasty in humans.
PubMed:
Determination of vitamin E in aquatic organisms by high-performance liquid chromatography with fluorescence detection.
PubMed:
Application of Photoacoustic Calorimetry to the Measurement of the O-H Bond Strength in Vitamin E (alpha- and delta-Tocopherol) and Related Phenolic Antioxidants(1).
PubMed:
Certification of fat-soluble vitamins, carotenoids, and cholesterol in human serum: Standard Reference Material 968b.
PubMed:
Variability of vitamin E content in pumpkin seeds (Cucurbita pepo L.).
PubMed:
Rapid quantification of alpha-tocopherol in plasma and low- and high-density lipoproteins.
PubMed:
Tocopherols in camel's plasma and tissues.
PubMed:
Plasma concentrations of carotenoids and tocopherols in male long-term tobacco chewers, smokers and nonusers.
PubMed:
Supplementation of broiler diets with all-rac-alpha- or a mixture of natural source RRR-alpha-,gamma-,delta-tocopheryl acetate. 2. Effect on the oxidative stability of raw and precooked broiler meat products.
PubMed:
Supplementation of broiler diets with all-rac-alpha- or a mixture of natural source RRR-alpha-,gamma-,delta-tocopheryl acetate. 1. effect on vitamin E status of broilers in vivo and at slaughter.
PubMed:
Population distributions and intralaboratory reproducibility for fat-soluble vitamin-related compounds in human serum.
PubMed:
Haemorrhagic toxicity of a large dose of alpha-, beta-, gamma- and delta-tocopherols, ubiquinone, beta-carotene, retinol acetate and L-ascorbic acid in the rat.
PubMed:
High-performance liquid chromatographic method for the simultaneous determination of tocopherols, carotenes, and retinol and its geometric isomers in Italian cheeses.
PubMed:
Bioefficiency of different tocopherols in chicken as assessed by haemolysis test and microsomal pentane production.
PubMed:
A liquid chromatographic method for the simultaneous determination of alpha-tocopherol and tocopherolquinone in human red blood cells and other biological samples where tocopherol is easily oxidized during sample treatment.
PubMed:
Liquid chromatographic method for the determination of carotenoids, retinoids and tocopherols in human serum and in food.
PubMed:
Purification and partial characterisation of an alpha-tocopherol-binding protein from rabbit heart cytosol.
PubMed:
[The biological activity of vitamin E].
PubMed:
The biological activity of natural source tocopherols in chickens fed fresh or oxidized fat rich in linoleic acid.
PubMed:
Isolation and properties of gamma-tocopherol methyltransferase in Euglena gracilis.
PubMed:
Determination of tocotrienol and tocopherol isomers at physiological concentration by HPLC in Caucasian and Japanese women.
PubMed:
One-dimensional and two-dimensional 1H- and 13C-nuclear magnetic resonance (NMR) analysis of vitamin E raw materials or analytical reference standards.
PubMed:
Functions of vitamin E in reproduction and in prostacyclin and immunoglobulin synthesis in rats.
PubMed:
Location of two antioxidants in oriented model membranes. Small-angle x-ray diffraction study.
PubMed:
Determination of tocopherols by reverse-phase liquid chromatography and electrochemical detection at a surface-oxide modified platinum microelectrode, without added electrolyte.
PubMed:
The oxidation products from two kinds of tocopherols co-existing in autoxidation system of methyl linoleate.
PubMed:
Physical and chemical scavenging of singlet molecular oxygen by tocopherols.
PubMed:
Vitamin E status in pediatric patients receiving antiepileptic drugs.
PubMed:
Quantitative determination of vitamin E and oxidized and reduced coenzyme Q by high-performance liquid chromatography with in-line ultraviolet and electrochemical detection.
PubMed:
Serum alpha-tocopherol levels after high-dose enteral vitamin E administration in patients with acute respiratory failure.
PubMed:
Simultaneous determination of tocopherols, ubiquinols, and ubiquinones in blood, plasma, tissue homogenates, and subcellular fractions.
PubMed:
Studies on the tocopherol status in blood serum of premature babies and infants.
PubMed:
Determination of vitamin E in microsamples of serum by liquid chromatography with electrochemical detection.
PubMed:
Tocopherols and tocotrienols in Finnish foods: human milk and infant formulas.
PubMed:
Vitamin E requirement of mink with special reference to tocopherol composition in plasma, liver, and adipose tissue.
PubMed:
Electron spin resonance and electron nuclear double resonance studies of cation radicals derived from tocopherol model compounds.
PubMed:
The fate of antioxidant radicals during lipid autooxidation. I. The tocopheroxyl radicals.
PubMed:
High-performance liquid chromatographic determination of tocopherols and tocotrienols and its application to diets and plasma of Finnish men. I. Analytical method.
PubMed:
[Determination of the tocopherol content of the nonsaponifiable fraction of lupine oil (L. mutabilis)].
PubMed:
Novel urinary metabolite of d-delta-tocopherol in rats.
PubMed:
Vitamin E as an antioxidant in vitro and in vivo.
PubMed:
Antioxidant activities of tocopherols on Fe2+-ascorbate-induced lipid peroxidation in lecithin liposomes.
PubMed:
Photosynthetic apparatus of chilling-sensitive plants. IX. The involvement of alpha-tocopherol in the electron transport chain and the anti-oxidizing system in chloroplasts of tomato leaves.
PubMed:
Oxidation by superoxide of tocopherols dispersed in aqueous media with deoxycholate.
PubMed:
Blood serum tocopherol levels in calves born from cows winter fed hay or grass silage.
PubMed:
Biological activity of vitamin E compounds and natural materials by the resorption-gestation test, and chemical determination of the vitamin E activity in foods and feeds.
PubMed:
Tocopherols in canned entrées and vended sandwiches.
PubMed:
Relative autoxidative and photolytic stabilities of tocols and tocotrienols.
PubMed:
Distribution of tocopherols in human plasma and red blood cells.
PubMed:
Identification of alpha-, beta-, gamma-, and delta-tocopherols and their contents in human milk.
PubMed:
[Effect of gamma-irradiation of vitamin E factors in solution. I. Tributyrin solution of alpha-tocopheryl acetate as well as alpha, beta-, gamma-, and delta-tocopherol].
PubMed:
Electron spin resonance of chromanoxy free radicals from alpha, zeta, beta, gamma, delta-tocopherol and tocol.
PubMed:
Biosynthesis of phytoquinones. Biosynthetic origins of the nuclei and satellite methyl groups of plastoquinone, tocopherols and tocopherolquinones in maize shoots, bean shoots and ivy leaves.
PubMed:
Synthesis and some toxicity and oxidation studies of a fatty acid hydroquinone and analogs of tocol and delta-tocopherol.
PubMed:
The isolation and properties of delta-tocotrienol from Hevea latex.
PubMed:
[ON THE METABOLISM OF ALPHA-, BETA + GAMMA- AND DELTA-TOCOPHEROL IN RATS].
PubMed:
[On the content of alpha-, beta plus gamma- and delta-tocopherol in the gastrointestinal tract, blood and urine of rats].
PubMed:
delta-Tocopherol; isolation from soybean oil and properties.
PubMed:
The presence of delta-tocopherol in hog fats.