pulegone oxide
cis-4,8-epoxy-p-menthan-3-one
Identification
| Name | pulegone oxide |
| IUPAC | 1,1,6-trimethyl-2-oxaspiro[2.5]octan-8-one |
| CAS Number | 17677-87-1 |
| FDA UNII | Search |
| Molecular Formula | C10 H16 O2 |
| Molecular Weight | 168.23592000 |
| Nikkaji Number | J1.316.495I |
Regulatory
Physical Properties
| Appearance | colorless to pale yellow clear liquid (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 245.00 to 246.00 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure | 0.029000 mmHg @ 25.00 °C. (est) |
| Flash Point | 208.00 °F. TCC ( 98.00 °C. ) (est) |
| logP (o/w) | 1.278 (est) |
| Soluble in | alcohol |
| Insoluble in | water |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for pulegone oxide usage levels up to | not for fragrance use. |
| Recommendation for pulegone oxide flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
cis-4,8-
epoxy-p-menthan-3-one
cis-4,8-
epoxy-para-menthan-3-one
2,2,6-
trimethyl-1-oxaspiro(2.5)octan-4-one
2,2,6-
trimethyl-1-oxaspiro[2.5]octan-4-one
1,1,6-
trimethyl-2-oxaspiro[2.5]octan-8-one
PubMed:
Essential oils of Micromeria dalmatica Benth., a Balkan endemic species of section Pseudomelissa.
PubMed:
In vitro production of M. Ã piperita not containing pulegone and menthofuran.
PubMed:
The constituents of essential oil: antimicrobial and antioxidant activity of Micromeria congesta Boiss. & Hausskn. ex Boiss. from East Anatolia.
PubMed:
Essential-oil diversity of three Calamintha species from Greece.
PubMed:
Intraspecific variability of the essential oil of Calamintha nepeta subsp. nepeta from Southern Italy (Apulia).
PubMed:
Chemical and morphological diversity in wild populations of Mentha longifolia in Israel.
PubMed:
Mentha longifolia in vitro cultures as safe source of flavouring ingredients.
PubMed:
Chemical composition and biological assays of essential oils of Calamintha nepeta (L.) Savi subsp. nepeta (Lamiaceae).
PubMed:
Composition and chemical variability of Mentha suaveolens ssp. suaveolens and M. suaveolens ssp. insularis from Corsica.
PubMed:
Chemical composition and antimicrobial and antioxidant activities of Mentha (longifolia L. and viridis) essential oils.
PubMed:
Structure and spasmolytic activity relationships of monoterpene analogues found in many aromatic plants.
PubMed:
Antinociceptive activity of structural analogues of rotundifolone: structure-activity relationship.
PubMed:
Chemical composition of the essential oil of Salvia microstegia Boiss. et Balansa growing wild in Lebanon.
PubMed:
On the mechanism of the Skraup-Doebner-Von Miller quinoline synthesis.
PubMed:
Immunomodulating properties of Minthostachys verticillata on human lymphocytes and basophils.
PubMed:
Analysis of volatile components from Ziziphora taurica subsp. taurica by steam distillation, superheated-water extraction, and direct thermal desorption with GCxGC-TOFMS.
PubMed:
Composition of the essential oil of Mentha microphylla from the Gennargentu Mountains (Sardinia, Italy).
PubMed:
Antibacterial and antifungal activity of essential oils of Mentha suaveolens.
PubMed:
The Volatile Constituents of Ziziphora taurica subsp. cleonioides.
PubMed:
Biotransformation of monoterpenes by Mentha cell lines.