Identification

Namenerolidol
IUPAC3,7,11-trimethyldodeca-1,6,10-trien-3-ol
CAS Number7212-44-4
EINECS230-597-5
FDA UNIIQR6IP857S6
Molecular FormulaC15 H26 O
Molecular Weight222.37142000
MDL NumberMFCD00008911
Beilstein1724135
CoE Number67

Regulatory

JECFA Food Flavoring1646 nerolidol
DG SANTE Food Flavourings02.018 nerolidol
FEMA Number2772
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)7212-44-4 ; NEROLIDOL
FDA RegulationFDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION

Physical Properties

Appearance colorless to pale yellow clear oily liquid (est)
Assay 96.00 to 100.00 sum of isomers
Food Chemicals Codex Listed Yes
Specific Gravity 0.87000 to 0.87600 @ 25.00 °C.
Pounds per Gallon - (est). 7.239 to 7.289
Refractive Index 1.47800 to 1.48300 @ 20.00 °C.
Optical Rotation -2.00 to +2.00
Boiling Point 114.00 °C. @ 1.00 mm Hg, 89.00 to 100.00 °C. @ 0.30 mm Hg
Vapor Pressure 0.001000 mmHg @ 25.00 °C. (est)
Vapor Density >1 ( Air = 1 )
Flash Point 205.00 °F. TCC ( 96.11 °C. )
logP (o/w) 4.682 (est)
Shelf Life 24.00 month(s) or longer if stored properly.
Storage store in cool, dry place in tightly sealed containers, protected from heat and light.
Soluble in alcohol
Insoluble in glycerin

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesperfuming agents

Organoleptic Properties

Odor Strength low
Substantivity 100 hour(s) at 100.00 %
Odor Description
at 100.00 %.
Floral, green and citrus like, with woody waxy nuances
woody, floral, green
Floral, woody, green
mild herbal-floral
mild herbal-floral soft-light-floral-woody muguet Woody Floral Green
Floral-neroli, green-citrus, woody, waxy. Fixative
Odor sample from Berje Inc.
Taste Description
at 25.00 ppm.
green
mild, woody, floral, green
Floral, fruity, woody and green notes

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Human Experience4 % solution: no irritation or sensitization.
Oral/Parenteral Toxicityoral-rat LD50 > 5000 mg/kg
Dermal Toxicityskin-rabbit LD50 > 5000 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavor and fragrance agents
RIFM Fragrance Material Safety AssessmentSearch
maximum skin levels for fine fragrances2.0200 % and are based on the assumption that the fragrance mixture is used at 20% in a consumer product (IFRA Use Level Survey). (IFRA, 2007)
Recommendation for nerolidol usage levels up to15.0000 % in the fragrance concentrate.
use level in formulae for use in cosmetics1.1500 %
Dermal Systemic Exposure in Cosmetic Products0.0293 mg/kg/day (IFRA, 2007)
Maximised Survey-derived Daily Intakes (MSDI-EU)43.00 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA)23.00 (μg/capita/day)
Modified Theoretical Added Maximum Daily Intake (mTAMDI)7000 (μg/person/day)
Threshold of Concern1800 (μg/person/day)
Structure ClassI
baked goods2.00000
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum-
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy-
fruit ices-
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-
Dairy products, excluding products of category 02.0 (01.0)2.00000
Fats and oils, and fat emulsions (type water-in-oil) (02.0)-
Edible ices, including sherbet and sorbet (03.0)2.00000
Processed fruit (04.1)-
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2)-
Confectionery (05.0)200.00000
Chewing gum (05.3)-
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0)2.00000
Bakery wares (07.0)2.00000
Meat and meat products, including poultry and game (08.0)-
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0)-
Eggs and egg products (10.0)-
Sweeteners, including honey (11.0)-
Salts, spices, soups, sauces, salads, protein products, etc. (12.0)1.00000
Foodstuffs intended for particular nutritional uses (13.0)-
Non-alcoholic ("soft") beverages, excl. dairy products (14.1)2.00000
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2)30.00000
Ready-to-eat savouries (15.0)2.00000
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0)-

Associate Allied Chemicals

Quality, Service and Values

Our aim is to become a reliable one-stop shop for our customers.

View All Website +91 22 2419 8800 aacipl@aacipl.com

Axxence Aromatic GmbH

We bring nature to your flavour

Dedicated to provide the best possible quality and supply service of natural aroma ingredients.

View All Website +49.2822.68561.0 service@axxence.com

Bedoukian Research, Inc.

Perfecting the Art of Chemistry

Working closely with our customers to meet their requirements.

View All Website 1-203-830-4000 customerservice@bedoukian.com

Berje Inc.

Where the world comes to its senses

Where the world comes to its senses - Berjé is a global distributor of Essential Oils and Aromatic Chemicals.

View All Website 973-748-8980 tlauzurica@berjeinc.com

BOC Sciences

Best of Chemicals Supplier

Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...

View All Website 1-631-485-4226 account@bocsci.com

Bontoux SAS

Major international supplier

Major international Producer of aromatic ingredients for the production of fragrances, flavors, cosmetics, pharmaceuticals and Aromatherapy.

View All Website + 1.908.755.4800 contact@bontoux.com

Excellentia International

Ingredients by Nature

Exceptional quality and excellence in meeting our customers requirements.

View All Website 732.749.9840 info@excellentiaint.com

Firmenich Inc.

We Create

We create perfumes and flavors for the World's most desirable brands.

View All Website +1 609 452 1000 Frederick.Keifer@firmenich.com

Fleurchem, Inc.

Have A Flavorful Day

A leading global manufacturer and supplier of ingredients for Flavors, Fragrances, AromaTherapy, Foods, Beverages, Personal Care Products, and other uses.

View All Website 845-341-2100 info@fleurchem.com

Foreverest Resources Ltd.

Leading pine based chemicals supplier

Supplying turpentine based and natural/extracted flavor & fragrance ingredients.

View All Website +86 (0)592 5105533 info@foreverest.cn

Hermitage Oils / Neroli S.R.L.

Perfumery and Aromatherapy materials since 1979

Hermitage Oils, the true home of essential oils!

View All Website info@hermitageoils.com

Indukern, S.A. F&F Ingredients Division

Commitment to quality

Idukern F&F Ingredients is your partner for the fragrance and flavor ingredients.

View All Website +34 93 506 91 00 info@indukern.es

Lluch Essence S.L.

A family company dedicated to sales and distribution

Flexibility, availability, price and quality.

View All Website 34 93 379 38 49 web@lluche.com

M&U International LLC

Steady supply & demand

Meeting customers increasing demands at home as well as abroad.

View All Website 908-359-9000 sales@mu-intel.com

Moellhausen S.P.A.

THE CHEMISTRY OF EMOTIONS

Innovation and commitment in the name of excellence.

View All Website +39 039.685.6262

Pell Wall Perfumes

Hand-made fragrances

Pell Wall maintains a broad palette of ingredients & in order to keep stocks fresh & the options wide we also sell from our own stock.

View All Website +44 (0) 20 3745 0887 https://pellwall.com/contact-us/

Penta International Corporation

Chemistry innovation

At Penta, our products and services help businesses do business better.

View All Website (973) 740-2300 lisaa@pentamfg.com

PerfumersWorld Ltd.

feeeel... the smell!

The one-stop resource for the creative perfumer.

View All Website +66(0)2-99-800-80 pwenquiries@perfumersworld.com

Prodasynth

PRODUCTEUR PAR ESSENCE

Chemical specialist in manufacturing, distributing and sourcing of tailor-made ingredients for the Flavour & Fragrance industry.

View All Website (33) 4 93 09 00 11 info@prodasynth.com

Robertet, Inc.

HOME OF NATURE, SEED TO SCENT

HOME OF NATURE – natural ingredients from the source.

View All Website +1.201.337.7100 info@robertetUSA.com

Sigma-Aldrich

Complete Supply Chain

The perfect blend of products and services that bring your creativity to life.

View All Website 800-244-1173 ff@sial.com

TCI AMERICA

Moving Your Chemistry Forward

We continuously strive to advance our technology.

View All Website 1-800-423-8616 Sales-US@TCIchemicals.com;

The John D. Walsh Company, Inc

Suppliers Since 1942

Supplying the fragrance and flavor industry with high quality products.

View All Website 973-962-1400 info@johndwalsh.com

R C Treatt and Co Ltd

Innovative ingredient solutions

World-leading innovative ingredient solutions provider for the flavour, fragrance and FMCG industries.

View All Website +1 863 668 9500 enquiries@treatt.com

Ernesto Ventós S.A.

Leaders in essence

We employ our five senses to do our job well.

View All Website +1 856 226 7501 info@ventos.com

Vigon International

Passion for Simplicity

Manufacturer and supplier of high quality flavor and fragrance ingredients.

View All Website 570-476-6300 sales@vigon.com

Zanos Ltd.

Distributor of Speciality Chemicals and Natural Ingredients

Sourcing and supplying quality aroma chemicals and prestige natural ingredients for the flavour and fragrance industry.

View All Website +44 (0) 1565 755899 sales@zanos.co.uk

Potential Uses

FR acacia FR apple FR balsam FR blueberry FR cabreuva wood FR clary sage oil replacer FR cologne FR currant FR cyclamen fixer FR grape FR grapefruit FR honeysuckle FR jasmin FR leather FR lilac FR lily FR lily of the valley FR melon FR neroli FR orange FR orange blossom FR peach FR pear FR peru balsam FR petitgrain FR raspberry FR rose FR spring rain FR strawberry FR tea green tea FR tolu balsam FR violet FR woody FR ylang ylang

Natural Occurrence

ambrette seed oil @ 0.40% Data anise seed oil star china @ 0.12% Data anise star anise fruit basil oil basil plant basil shoot oil basswood flower beer PMC bergamot oil @ 0.02% Data cabreuva oil @ 1.86-2.05% Data cananga odorata oil java @ 0.15% Data cardamom fruit cardamom oil CO2 extract guatemala @ 1.50% Data cardamom seed oil cardamom seed oil @ trace% Data carrot seed oil spain @ 0.04-0.09% Data cascarilla bark oil @ 0.05% Data chamomile garden chamomile plant chamomile oil morocco @ 0.30% Data cinnamon fruit oil india @ 0.2-0.4% Data clary sage oil greece @ trace% Data coriander fruit coriander seed cornmint oil india @ 0.02% Data galangal root oil @ 0.04% Data ginger oil ginger rhizome ginger rhizome oil ginger root oil china @ 0.92% Data gingergrass oil @ 0.09% Data grapefruit oil california @ 0.03% Data guava fruit oil reunion @ 18.00% Data jasmin absolute china @ 0.70% Data jasmin absolute concrete india @ 1.84-2.46% Data jasmin absolute concrete italy @ 0.16% Data jasmin oil italy @ 0.05% Data lemon oil california @ 0.004% Data lemon verbena oil morocco @ 1.2% Data lemon verbena oil turkey @ 0.73% Data mandarin marjoram oil sweet egypt @ 0.15% Data melon bitter melon seed oil michelia champaca flower absolute @ 1.18% Data neroli PMC nutmeg flower oil @ 0.96% Data nutmeg leaf oil @ 0.00-1.86% Data orange flower orange fruit orange peel oil bitter china @ 0.02% Data orangeflower absolute morocco @ 4.9-8.9% Data orangeflower water absolute @ 0.0-1.5% Data osmanthus absolute @ 0.21% Data parsley leaf oil @ 0.02% Data parsley leaf oil cuba @ 0.03% Data pepper black pepper fruit pepper black pepper fruit oil pepper oil black india @ 3.00% Data peppermint leaf petitgrain bigarade oil @ 0.10% Data petitgrain mandarin oil @ 0.02% Data plectranthus glandulosus hook f. leaf oil cameroon @ 0.20% Data plum fruit plumcot fruit PMC pomelo sideritis montana l. oil bulgaria @ 0.80% Data sideritis scardica l. oil bulgaria @ 12.10% Data skimmia laureola oil @ 0.4% Data stachys recta l. oil serbia @ 3.60% Data strawberry wild strawberry fruit tarragon shoot tea green tea tea leaf tea shoot thyme oil wild or creeping france @ 7.00% Data thyme plant water mint shoot ylang ylang ylang ylang oil CO2 extract @ 0.02% Data yuzu leaf oil @ 0.23-0.28% Data

Synonyms

dodecatriene 3- hydroxy-3,7,11-trimethyl-1,6,10-dodecatriene melaleucol methyl vinyl homogeranyl carbinol nerolidol nat nerolidol natural nerolidol natural isolate nerolidol naturel nerolidol paraguay, natural isolated constituent nerolidol pure FCC nerolidol synthetic 3,7,11- trimethyl dodeca-1,6,10-trien-3-ol 3,7,11- trimethyl-1,6,10-dodecatrien-3-ol 3,7,11- trimethyldodeca-1,6,10-trien-3-ol PubMed: Tomato terpene synthases TPS5 and TPS39 account for a monoterpene linalool production in tomato fruits. J-Stage: Characterization of Essential Oil from Citrus aurantium L. Flowers: Antimicrobial and Antioxidant Activities PubMed: Chemical composition of essential oils from four Vietnamese species of piper (piperaceae). J-Stage: In Vivo Transdermal Delivery of Diclofenac by Ion-Exchange Iontophoresis with Geraniol PubMed: Repellent Activities of Essential Oils of Some Plants Used Traditionally to Control the Brown Ear Tick, Rhipicephalus appendiculatus. J-Stage: Antifungal Effect of Eugenol and Nerolidol against Microsporum gypseum in a Guinea Pig Model PubMed: Simple and short synthesis of trans-(R)-nerolidol, a pheromone component of fruit spotting bug. J-Stage: Enzymatic Formation of Nerolidol in Cell-Free Extract of Rhodotorula glutinis PubMed: Antischistosomal activity of the terpene nerolidol. PubMed: Volatile organic compounds of six French Dryopteris species: natural odorous and bioactive resources. PubMed: Assessment of the antioxidant and antiproliferative effects of sesquiterpenic compounds in in vitro Caco-2 cell models. PubMed: Terpene constituents of the leaves of five Vietnamese species of Clausena (Rutaceae). PubMed: A novel nerolidol-rich essential oil from Piper claussenianum modulates Candida albicans biofilm. PubMed: Design and evaluation of polysaccharide-based transdermal films for the controlled delivery of nifedipine. PubMed: A new source of elemol rich essential oil and existence of multicellular oil glands in leaves of the Dioscorea species. PubMed: Determination of nerolidol in teas using headspace solid phase microextraction-gas chromatography. PubMed: Hedycaryol synthase in complex with nerolidol reveals terpene cyclase mechanism. PubMed: Essential oils composition of croton species from the Amazon. PubMed: Inhibition of acetylcholinesterases of the pinewood nematode, Bursaphelenchus xylophilus, by phytochemicals from plant essential oils. PubMed: In vitro acaricidal efficacy of plant extracts from Brazilian flora and isolated substances against Rhipicephalus microplus (Acari: Ixodidae). PubMed: Effect of terpenes on the skin permeation of lomerizine dihydrochloride. PubMed: Hepatoprotection of sesquiterpenoids: a quantitative structure-activity relationship (QSAR) approach. PubMed: Chemical composition and in vitro antimicrobial and antioxidant activities of Citrus aurantium l. flowers essential oil (Neroli oil). PubMed: Chemical composition and biological activities of the essential oil of Athanasia brownii Hochr. (Asteraceae) endemic to Madagascar. PubMed: Bacteria isolated from roots and rhizosphere of Vitis vinifera retard water losses, induce abscisic acid accumulation and synthesis of defense-related terpenes in in vitro cultured grapevine. PubMed: Volatile analysis and antimicrobial screening of the parasitic plant Cuscuta reflexa Roxb. from Nepal. PubMed: Characterization of essential oil from Citrus aurantium L. flowers: antimicrobial and antioxidant activities. PubMed: Nematicidal activity of the essential oil of Rhododendron anthopogonoides aerial parts and its constituent compounds against Meloidogyne incognita. PubMed: Antimicrobial activity of essential oils and five terpenoid compounds against Campylobacter jejuni in pure and mixed culture experiments. PubMed: Metabolic engineering of the C16  homoterpene TMTT in Lotus japonicus through overexpression of (E,E)-geranyllinalool synthase attracts generalist and specialist predators in different manners. PubMed: Enhancement of 4-acetylantroquinonol B production by supplementation of its precursor during submerged fermentation of Antrodia cinnamomea. PubMed: Impacts of chemical enhancers on skin permeation and deposition of terbinafine. PubMed: Antioxidant effects of nerolidol in mice hippocampus after open field test. PubMed: Chrysanthemum expressing a linalool synthase gene 'smells good', but 'tastes bad' to western flower thrips. PubMed: A chemotaxonomic study of endemic species of genus Tanacetum from the Canary Islands. PubMed: Optimization and characterization of chitosan films for transdermal delivery of ondansetron. PubMed: Chemical composition, cytotoxic and antimicrobial activity of essential oils from Cassia bakeriana Craib. against aerobic and anaerobic oral pathogens. PubMed: A phthalate family oxygenase reductase supports terpene alcohol oxidation by CYP238A1 from Pseudomonas putida KT2440. PubMed: Chemical composition, antifungal and insecticidal activities of Hedychium essential oils. PubMed: Phytochemical diversity of Murraya koenigii (L.) Spreng. from Western Himalaya. PubMed: In vitro sensitivity of poultry Brachyspira intermedia isolates to essential oil components and in vivo reduction of Brachyspira intermedia in rearing pullets with cinnamaldehyde feed supplementation. PubMed: Cytotoxic mechanism of Piper gaudichaudianum Kunth essential oil and its major compound nerolidol. PubMed: Synergistic effect of iontophoresis and chemical enhancers on transdermal permeation of tolterodine tartrate for the treatment of overactive bladder. PubMed: Steps in the biosynthesis of fuscumol in the longhorn beetles Tetropium fuscum (F.) and Tetropium cinnamopterum Kirby. PubMed: Antibacterial/antifungal activity and synergistic interactions between polyprenols and other lipids isolated from Ginkgo biloba L. leaves. PubMed: Insecticidal and biting deterrent activity of rose-scented geranium (Pelargonium spp.) essential oils and individual compounds against Stephanitis pyrioides and Aedes aegypti. PubMed: The case of Hypericum rochelii Griseb. & Schenk and Hypericum umbellatum A. Kern. essential oils: chemical composition and antimicrobial activity. PubMed: Terpenes: Effect of lipophilicity in enhancing transdermal delivery of alfuzosin hydrochloride. PubMed: Specific involvement of two amino acid residues in cis-nerolidol binding to odorant-binding protein 5 AlinOBP5 in the alfalfa plant bug, Adelphocoris lineolatus (Goeze). PubMed: Volatile oil constituents of different parts of Artemisia chamaemelifolia and the composition and antibacterial activity of the aerial parts of A. turcomanica from Iran. PubMed: Composition of the essential oils from Peucedanum cervaria and P. alsaticum growing wild in the urban area of Vienna (Austria). PubMed: Three-step pathway engineering results in more incidence rate and higher emission of nerolidol and improved attraction of Diadegma semiclausum. PubMed: QTL mapping of the production of wine aroma compounds by yeast. PubMed: Metabolism by grasshoppers of volatile chemical constituents from Mangifera indica and Solanum paniculatum leaves. PubMed: Nematicidal activity of terpenoids. PubMed: Analysis of the essential oil of large cardamom (Amomum subulatum Roxb.) growing in different agro-climatic zones of Himachal Pradesh, India. PubMed: Chemical characterization of volatile compounds of Lantana camara L. and L. radula Sw. and their antifungal activity. PubMed: Volatiles from apple trees infested with light brown apple moth larvae attract the parasitoid Dolichogenidia tasmanica. PubMed: Toxicity of terpenes on fibroblast cells compared to their hemolytic potential and increase in erythrocyte membrane fluidity. PubMed: Genetic engineering of plant volatile terpenoids: effects on a herbivore, a predator and a parasitoid. PubMed: Sensitivity of pathogenic and commensal bacteria from the human colon to essential oils. PubMed: Activity of tea tree oil and nerolidol alone or in combination against Pediculus capitis (head lice) and its eggs. PubMed: Biosynthesis of wine aroma: transcript profiles of hydroxymethylbutenyl diphosphate reductase, geranyl diphosphate synthase, and linalool/nerolidol synthase parallel monoterpenol glycoside accumulation in Gewürztraminer grapes. PubMed: Aerosol delivery of trail pheromone disrupts the foraging of the red imported fire ant, Solenopsis invicta. PubMed: Chemical composition of essential oils from a multiple shoot culture of Telekia speciosa and different plant organs. PubMed: Chemical composition and antioxidant and anticandidal activities of essential oils from different wild Moroccan Thymus species. PubMed: Transdermal behaviors comparisons among Evodia rutaecarpa extracts with different purity of evodiamine and rutaecarpine and the effect of topical formulation in vivo. PubMed: Activity of compounds isolated from Baccharis dracunculifolia D.C. (Asteraceae) against Paracoccidioides brasiliensis. PubMed: Genetic variation and evolution of secondary compounds in native and introduced populations of the invasive plant Melaleuca quinquenervia. PubMed: [Analyze on chemical compositions of Dalbergia odorifera essential oils extracted by CO2-supercritical-fluid-extraction and steam distillation extraction]. PubMed: Chemical diversity of essential oils from Asteriscus graveolens (Forssk.) less.: identification of cis-8-Acetoxychrysanthenyl acetate as a new natural component. PubMed: Chemical composition, antimicrobial, antiradical and anticholinesterase activity of the essential oil of Pulicaria stephanocarpa from Soqotra. PubMed: Acaricidal activity and repellency of essential oil from Piper aduncum and its components against Tetranychus urticae. PubMed: Understanding Darjeeling tea flavour on a molecular basis. PubMed: Metabolism of terpenes in the response of grape (Vitis vinifera L.) leaf tissues to UV-B radiation. PubMed: Identification, functional characterization, and regulation of the enzyme responsible for floral (E)-nerolidol biosynthesis in kiwifruit (Actinidia chinensis). PubMed: Toxicity of Rhododendron anthopogonoides essential oil and its constituent compounds towards Sitophilus zeamais. PubMed: Nerolidol effects on mitochondrial and cellular energetics. PubMed: Herbivore-induced volatiles from tea (Camellia sinensis) plants and their involvement in intraplant communication and changes in endogenous nonvolatile metabolites. PubMed: Chemical constituents of the rhizomes of Hedychium coronarium and their inhibitory effect on the pro-inflammatory cytokines production LPS-stimulated in bone marrow-derived dendritic cells. PubMed: Effect of exogenous administration of Candida albicans autoregulatory alcohols in a murine model of hematogenously disseminated candidiasis. PubMed: Chemical composition, antinociceptive and anti-inflammatory effects in rodents of the essential oil of Peperomia serpens (Sw.) Loud. PubMed: Analysis of essential oils from Scutellaria orientalis ssp. alpina and S. utriculata by GC and GC-MS. PubMed: Chemical composition and insecticidal activity of essential oils of two aromatic plants from Ivory Coast against Bemisia tabaci G. (Hemiptera: Aleyrodidae). PubMed: Identification and characterization of the linalool/nerolidol synthase from Streptomyces clavuligerus. PubMed: Comparative studies of volatile oil composition of Rhododendron anthopogon by hydrodistillation, supercritical carbon dioxide extraction and head space analysis. PubMed: Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. PubMed: A morphogenetic regulatory role for ethyl alcohol in Candida albicans. PubMed: Chemical composition, cytotoxicity effect and antimicrobial activity of Ceratonia siliqua essential oil with preservative effects against Listeria inoculated in minced beef meat. PubMed: Conversion of airborne nerolidol to DMNT emission requires additional signals in Achyranthes bidentata. PubMed: Four terpene synthases produce major compounds of the gypsy moth feeding-induced volatile blend of Populus trichocarpa. PubMed: Larvicidal activity of Myrtaceae essential oils and their components against Aedes aegypti, acute toxicity on Daphnia magna, and aqueous residue. PubMed: Evaluation of the mutagenicity of sesquiterpenic compounds and their influence on the susceptibility towards antibiotics of two clinically relevant bacterial strains. PubMed: Comparison of volatile constituents, and antioxidant and antibacterial activities of the essential oils of Thymus caucasicus, T. kotschyanus and T. vulgaris. PubMed: The biochemistry of homoterpenes--common constituents of floral and herbivore-induced plant volatile bouquets. PubMed: Volatile oil composition of Pogostemon heyneanus and comparison of its composition with patchouli oil. PubMed: Sex-pairing pheromones and reproductive isolation in three sympatric Cornitermes species (Isoptera, Termitidae, Syntermitinae). PubMed: Seasonal variation in the chemical composition and antimicrobial activity of volatile oils of three species of Leptospermum (Myrtaceae) grown in Brazil. PubMed: Chemical composition of essential oils from leaves, stems, flower heads and roots of Conyza bonariensis L. from Tunisia. PubMed: Chemistry and biological activity of essential oils from Piper claussenianum (Piperaceae). PubMed: Essential oil composition of three Australian endemic species of Darwinia (Myrtaceae). PubMed: Volatile emissions from Alnus glutionosa induced by herbivory are quantitatively related to the extent of damage. PubMed: Aristolactams and Alkamides of Aristolochia gigantea. PubMed: Biodiversity of volatile organic compounds from five French ferns. PubMed: The effect of terpenes on percutaneous absorption of tiaprofenic acid gel. PubMed: In vivo genotoxicity assessment of nerolidol. PubMed: Herbivore-induced and floral homoterpene volatiles are biosynthesized by a single P450 enzyme (CYP82G1) in Arabidopsis. PubMed: In vitro and in vivo activity of three sesquiterpenes against L(3) larvae of Anisakis type I. PubMed: Pharmacological interactions of essential oil constituents on the viability of micro-organisms. PubMed: Composition of volatile organic compounds in flowers of Astragalus sahendi. PubMed: Volatile constituents of two rare subspecies of Thymus praecox. PubMed: Hydrophobic constituents and their potential anticancer activities from Devil's Club (Oplopanax horridus Miq.). PubMed: Quantitative analysis of six polyynes and one polyene in Oplopanax horridus and Oplopanax elatus by pressurized liquid extraction and on-line SPE-HPLC. PubMed: Volatile compounds with characteristic odour in moso-bamboo stems (Phyllostachys pubescens Mazel ex Houz. De ehaie). PubMed: The molecular basis of host plant selection in Melaleuca quinquenervia by a successful biological control agent. PubMed: Volatile compounds and the changes in their concentration levels during storage in beers containing varying malt concentrations. PubMed: Composition and immunotoxicity activity of essential oils from Lindera obtusiloba Blume against Aedes aegypti L. PubMed: Candida species extracellular alcohols: production and effect in sessile cells. PubMed: Antiprotozoal, schistosomicidal, and antimicrobial activities of the essential oil from the leaves of Baccharis dracunculifolia. PubMed: Essential-oil composition, antileishmanial, and toxicity study of Artemisia abyssinica and Satureja punctata ssp. punctata from Ethiopia. PubMed: [Effects of azadirachtin on rice plant volatiles induced by Nilaparvata lugens]. PubMed: Trypanocidal and antileukaemic effects of the essential oils of Hagenia abyssinica, Leonotis ocymifolia, Moringa stenopetala, and their main individual constituents. PubMed: The tea weevil, Myllocerinus aurolineatus, is attracted to volatiles induced by conspecifics. PubMed: Composition and anti-wood-decay fungal activities of the leaf essential oil of Machilus philippinensis from Taiwan. PubMed: Sesquiterpenes from Oplopanax horridus. PubMed: Bisabolyl-derived sesquiterpenes from tobacco 5-epi-aristolochene synthase-catalyzed cyclization of (2Z,6E)-farnesyl diphosphate. PubMed: Essential oil composition of Achillea clusiana from Bulgaria. PubMed: Inhibitory effect of terpene nerolidol on the growth of Babesia parasites. PubMed: Effects of immunotoxic activity of the major essential oil of Angelica purpuraefolia Chung against Aedes aegypti L. PubMed: Addendum to Fragrance material review on Nerolidol (isomer unspecified). PubMed: Treatment of head lice with dimeticone 4% lotion: comparison of two formulations in a randomised controlled trial in rural Turkey. PubMed: Essential oil composition from two species of Piperaceae family grown in Colombia. PubMed: Chemical variation in Piper aduncum and biological properties of its dillapiole-rich essential oil. PubMed: Terpenoid diversity in the leaf essential oils of Himalayan Lauraceae species. PubMed: Volatile constituents of the leaves of Munnozia senecionidis from the Venezuelan Andes. PubMed: Different approaches for improving skin accumulation of topical corticosteroids. PubMed: Composition of essential oils from leaves and flowers of Stachys germanica subsp. salviifolia (Ten.) gams (Labiatae) and related secretory structures. PubMed: Alkaline pH enhances farnesol production by Saccharomyces cerevisiae. PubMed: Chemical composition and cytotoxic, mutagenic and genotoxic activities of the essential oil from Pipergaudichaudianum Kunth leaves. PubMed: Attraction of New Zealand flower thrips, Thrips obscuratus, to cis-jasmone, a volatile identified from Japanese honeysuckle flowers. PubMed: Linalool decreases HepG2 viability by inhibiting mitochondrial complexes I and II, increasing reactive oxygen species and decreasing ATP and GSH levels. PubMed: Essential oil composition of three Peperomia species from the Amazon, Brazil. PubMed: Effect of citral, eugenol, nerolidol and alpha-terpineol on the ultrastructural changes of Trichophyton mentagrophytes. PubMed: In vivo transdermal delivery of diclofenac by ion-exchange iontophoresis with geraniol. PubMed: Floral and insect-induced volatile formation in Arabidopsis lyrata ssp. petraea, a perennial, outcrossing relative of A. thaliana. PubMed: [Simultaneous determination of water-soluble components and nerolidol in xiangdan injection by high performance liquid chromatography with column switching]. PubMed: Quantification approach for assessment of sparkling wine volatiles from different soils, ripening stages, and varieties by stir bar sorptive extraction with liquid desorption. PubMed: Phenology of semiochemical-mediated host foraging by the western boxelder bug, Boisea rubrolineata, an aposematic seed predator. PubMed: Overexpression of the gene encoding HMG-CoA reductase in Saccharomyces cerevisiae for production of prenyl alcohols. PubMed: Enhancement of Escherichia coli and Staphylococcus aureus antibiotic susceptibility using sesquiterpenoids. PubMed: Matrix-type transdermal patches of verapamil hydrochloride: in vitro permeation studies through excised rat skin and pharmacodynamic evaluation in rats. PubMed: Fragrance material review on nerolidol (isomer unspecified). PubMed: Fragrance material review on cis-nerolidol. PubMed: Essential Oil Composition and Antibacterial Studies of Vitex negundo Linn. Extracts. PubMed: Synthesis of cordiaquinones B, C, J, and K on the basis of a bioinspired approach and the revision of the relative stereochemistry of cordiaquinone C. PubMed: Two nearly identical terpene synthases catalyze the formation of nerolidol and linalool in snapdragon flowers. PubMed: Volatile components of Discaria americana Gillies & Hook (Rhamnaceae). PubMed: The influence of different nutrient levels on insect-induced plant volatiles in Bt and conventional oilseed rape plants. PubMed: Chemical composition and antimicrobial activity of Momordica charantia seed essential oil. PubMed: Phytochemical analysis of the essential oil of Thymus serpyllum L. growing wild in Estonia. PubMed: Essential oil composition of the different parts of Eryngium corniculatum Lam. (Apiaceae) from Spain. PubMed: Bioactivity and chemical composition of the leaf essential oils of Zanthoxylum rhoifolium and Zanthoxylum setulosum from Monteverde, Costa Rica. PubMed: Morphogenesis control in Candida albicans and Candida dubliniensis through signaling molecules produced by planktonic and biofilm cells. PubMed: Herbivore-induced terpenoid emission in Medicago truncatula: concerted action of jasmonate, ethylene and calcium signaling. PubMed: Nerolidol, an antiulcer constituent from the essential oil of Baccharis dracunculifolia DC (Asteraceae). PubMed: Anti-inflammation activities of essential oil and its constituents from indigenous cinnamon (Cinnamomum osmophloeum) twigs. PubMed: Jacaranone: a cytotoxic constituent from Senecio ambiguus subsp. ambiguus (biv.) DC. against renal adenocarcinoma ACHN and prostate carcinoma LNCaP cells. PubMed: Tomato linalool synthase is induced in trichomes by jasmonic acid. PubMed: Analysis of wine primary aroma compounds by stir bar sorptive extraction. PubMed: Composition and cytotoxic activity of the leaf essential oil of Comptonia peregrina (L.) Coulter. PubMed: Hypoglycemic effects of a sesquiterpene glycoside isolated from leaves of loquat (Eriobotrya japonica (Thunb.) Lindl.). PubMed: Analysis of leaf volatiles of Zanthoxylum gillettii used in folk medicine of Cameroon. PubMed: Essential oils of three Baccharis species. PubMed: Expression of plant flavor genes in Lactococcus lactis. PubMed: Antifungal effect of eugenol and nerolidol against Microsporum gypseum in a guinea pig model. PubMed: The effect of terpene concentrations on the skin penetration of diclofenac sodium. PubMed: Essential oil from two populations of Echinodorus grandiflorus Micheli. PubMed: Environmental factors influence on chemical polymorphism of the essential oils of Lychnophora ericoides. PubMed: Lethality of essential oil constituents towards the human louse, Pediculus humanus, and its eggs. PubMed: Dynamic pathway allocation in early terpenoid biosynthesis of stress-induced lima bean leaves. PubMed: Antitrypanosomal compounds from the leaf essential oil of Strychnos spinosa. PubMed: Biosynthesis of mono- and sesquiterpenes in strawberry fruits and foliage: 2H labeling studies. PubMed: Analysis of atmospheric sesquiterpenes: sampling losses and mitigation of ozone interferences. PubMed: Optimization of pressurized liquid extraction of Piper gaudichaudianum Kunth leaves. PubMed: Secondary metabolites from Ganoderma lucidum and Spongiporus leucomallellus. PubMed: Five labdane diterpenoids from the seeds of Aframomum zambesiacum. PubMed: Microarray expression profiling and functional characterization of AtTPS genes: duplicated Arabidopsis thaliana sesquiterpene synthase genes At4g13280 and At4g13300 encode root-specific and wound-inducible (Z)-gamma-bisabolene synthases. PubMed: Chemical composition and pharmacological activity of essential oil of Canarium schweinfurthii. PubMed: Chemistry and geographic variation of floral scent in Yucca filamentosa (Agavaceae). PubMed: Genetic engineering of terpenoid metabolism attracts bodyguards to Arabidopsis. PubMed: Plant science. New gene boosts plant's defenses against pests. PubMed: Essential oil from Zanthoxylum hyemale. PubMed: [Determination of nerolidol in volatile oil of Dalbergia odorifera by GC]. PubMed: Bioavailability of nerodilol-based transdermal therapeutic system of nicorandil in human volunteers. PubMed: Identification, molecular cloning and functional characterization of an octaprenyl pyrophosphate synthase in intra-erythrocytic stages of Plasmodium falciparum. PubMed: Biomimetic synthesis of acid-sensitive (-)- and (+)-caparrapi oxides, (-)- and (+)-8-epicaparrapi oxides, and (+)-dysifragin induced by artificial cyclases. PubMed: Antileishmanial activity of the terpene nerolidol. PubMed: Biomimetic synthesis of acid-sensitive (-)-caparrapi oxide and (+)-8-epicaparrapi oxide induced by artificial cyclases. PubMed: Screening for key odorants in Moroccan green olives by gas chromatography-olfactometry/aroma extract dilution analysis. PubMed: Priority of color over scent during flower visitation by adult Vanessa indica butterflies. PubMed: Analysis of strawberry volatiles using comprehensive two-dimensional gas chromatography with headspace solid-phase microextraction. PubMed: Volatile organic compounds as signals in a plant-herbivore system: electrophysiological responses in olfactory sensilla of the moth Cactoblastis cactorum. PubMed: The nonmevalonate pathway supports both monoterpene and sesquiterpene formation in snapdragon flowers. PubMed: Vanadium bromoperoxidase-catalyzed biosynthesis of halogenated marine natural products. PubMed: Gain and loss of fruit flavor compounds produced by wild and cultivated strawberry species. PubMed: Essential oil composition of aerial parts of Angelica glauca growing wild in North-West Himalaya (India). PubMed: Determination of key odorant compounds in freshly distilled cognac using GC-O, GC-MS, and sensory evaluation. PubMed: The antibacterial effects of terpene alcohols on Staphylococcus aureus and their mode of action. PubMed: Jasmonic acid is a key regulator of spider mite-induced volatile terpenoid and methyl salicylate emission in tomato. PubMed: Content and composition of the essential oil of Thymus serpyllum L. growing wild in Estonia. PubMed: Tissue factor inhibitory sesquiterpene glycoside from Eriobotrya japonica. PubMed: Volatile constituents of the flower and fruit oils of Pittosporum tobira (Thunb.) Ait. grown in Iran. PubMed: Terpenes arrest parasite development and inhibit biosynthesis of isoprenoids in Plasmodium falciparum. PubMed: High-performance liquid chromatography and thin-layer chromatography assays for Devil's Club (Oplopanax horridus). PubMed: Differential timing of spider mite-induced direct and indirect defenses in tomato plants. PubMed: Essential oils from the leaves of three New Zealand species of Pseudopanax (Araliaceae). PubMed: Characterization of nerolidol biotransformation based on indirect on-line estimation of biomass concentration and physiological state in batch cultures of Aspergillus niger. PubMed: Terpenoid metabolism in wild-type and transgenic Arabidopsis plants. PubMed: Sensitization of Staphylococcus aureus and Escherichia coli to antibiotics by the sesquiterpenoids nerolidol, farnesol, bisabolol, and apritone. PubMed: Electroantennographic and behavioral responses of the sphinx moth Manduca sexta to host plant headspace volatiles. PubMed: Release and skin permeation studies of Naproxen from hydrophillic gels and effect of terpenes as enhancers on its skin permeation. PubMed: Chemical analysis of the swarming trail pheromone of the social wasp Polybia sericea (Hymenoptera: Vespidae). PubMed: Electroantennogram responses of Douglas-fir seed chalcids to plant volatiles. PubMed: Interspecific variation in terpenoid composition of defensive secretions of European Reticulitermes termites. PubMed: Dietary influences on terpenoids sequestered by the biological control agent Oxyops vitiosa: effect of plant volatiles from different Melaleuca quinquenervia chemotypes and laboratory host species. PubMed: [Study on the chemical constituents of the volatile oil from Lysimachia trientaloides Hemsl]. PubMed: Activity and mechanisms of action of selected biocidal agents on Gram-positive and -negative bacteria. PubMed: The maize gene terpene synthase 1 encodes a sesquiterpene synthase catalyzing the formation of (E)-beta-farnesene, (E)-nerolidol, and (E,E)-farnesol after herbivore damage. PubMed: In vitro efficacy of plant volatiles for inhibiting the growth of fruit and vegetable decay microorganisms. PubMed: African elephant sesquiterpenes. II. Identification and synthesis of new derivatives of 2,3-dihydrofarnesol. PubMed: Antiplasmodial activity of labdanes from Aframomum latifolium and Aframomum sceptrum. PubMed: Volatile compounds emitted by sclerotia of Sclerotinia minor, Sclerotinia sclerotiorum, and Sclerotium rolfsii. PubMed: Three labdane diterpenoids from Aframomum sceptrum (Zingiberaceae). PubMed: Characterization of the isoprenoid chain of coenzyme Q in Plasmodium falciparum. PubMed: Quorum sensing in the dimorphic fungus Candida albicans is mediated by farnesol. PubMed: Sesquiterpene hydrocarbons with trifarane backbone in the liverwort Trocholejeunea sandvicensis. PubMed: A chemotaxonomic investigation of volatile constituents in Stachys subsect. Swainsonianeae (Labiatae). PubMed: Characterization of the odor-active volatiles in citrus Hyuganatsu (Citrus tamurana Hort. ex Tanaka). PubMed: The effects of terpene enhancers on the percutaneous permeation of drugs with different lipophilicities. PubMed: Composition and antimicrobial activity of the essential oil of Scutellaria albida ssp. albida from Greece. PubMed: Bioactive sesquiterpenes from the basidiomycete Resupinatus leightonii. PubMed: Effect of formulation variables on the percutaneous permeation of ketoprofen from gel formulations. PubMed: Demonstration and characterization of (E)-nerolidol synthase from maize: a herbivore-inducible terpene synthase participating in (3E)-4,8-dimethyl-1,3,7-nonatriene biosynthesis. PubMed: The effect of terpene enhancer lipophilicity on the percutaneous permeation of hydrocortisone formulated in HPMC gel systems. PubMed: Antimalarial use of volatile oil from leaves of Virola surinamensis (Rol.) Warb. by Waiãpi Amazon Indians. PubMed: Cytotoxic sesquiterpenoids from Ratibida columnifera. PubMed: Cloning, expression, and characterization of epi-cedrol synthase, a sesquiterpene cyclase from Artemisia annua L. PubMed: Spider mite-induced (3S)-(E)-nerolidol synthase activity in cucumber and lima bean. The first dedicated step in acyclic C11-homoterpene biosynthesis. PubMed: A chromene and prenylated benzoic acid from Piper aduncum. PubMed: Activators of the nuclear hormone receptors PPARalpha and FXR accelerate the development of the fetal epidermal permeability barrier. PubMed: [Study of supercritical-CO2 fluid extraction in extracting essential oils of Amomun tsao-ko]. PubMed: Field attraction ofBiprorulus bibax Breddin (Hemiptera: Pentatomidae) to synthetic aggregation pheromone and (E)-2-hexenal, a pentatomid defense chemical. PubMed: Chemical and biological studies on two Helichrysum species of Greek origin. PubMed: Terpene penetration enhancers in propylene glycol/water co-solvent systems: effectiveness and mechanism of action. PubMed: Chemically mediated ovipositional behaviors of the european corn borer,Ostrinia nubilalis (Lepidoptera: Pyralidae). PubMed: Purification and some of the properties of a novel secondary alcohol dehydrogenase from Alcaligenes eutrophus. PubMed: Wide-angle X-ray diffraction of human stratum corneum: effects of hydration and terpene enhancer treatment. PubMed: Identification of farnesol as the non-sterol derivative of mevalonic acid required for the accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. PubMed: Sesquiterpene components of volatile oils as skin penetration enhancers for the hydrophilic permeant 5-fluorouracil. PubMed: Flight-mediated attraction ofBiprorulus bibax breddin (Hemiptera: Pentatomidae) to natural and synthetic aggregation pheromone. PubMed: Male-specific volatiles from nearctic and Australasian true bugs (Heteroptera: Coreidae and Alydidae). PubMed: A new pathway for the degradation of a sesquiterpene alcohol, nerolidol by Alcaligenes eutrophus. PubMed: Microbial formation of caparrapidiol and derivatives from trans-nerolidol. PubMed: Protein-linked isoprenoid lipids in dexamethasone-treated human lymphoid lines in culture. PubMed: Biologically active gamma-lactones and methylketoalkenes from Lindera benzoin. PubMed: Chemistryvis-à-vis maternalism in lace bugs (Heteroptera: Tingidae): Alarm pheromones and exudate defense inCorythucha andGargaphia species. PubMed: Isolation and identification of allelochemicals that attract the larval parasitoid,Cotesia marginiventris (Cresson), to the microhabitat of one of its hosts. PubMed: Cell-cycle-dependent, differential prenylation of proteins. PubMed: Inhibition of azoxymethane-induced neoplasia of the large bowel by 3-hydroxy-3,7,11-trimethyl-1,6,10-dodecatriene (nerolidol). PubMed: Olfactory sensitivity of two sympatric species of rice leaf folders (Lepidoptera: Pyralidae) to plant volatiles. PubMed: Characterization of isoprenoid involved in the post-translational modification of mammalian cell proteins. PubMed: Microbial transformations of some monoterpenoids and sesquiterpenoids. PubMed: (Z,E)-α-farnesene: Major component of secretion from metathoracic scent gland of cotton seed bug,Oxycarenus hyalinipennis (Costa) (Heteroptera; Lygaeidae). PubMed: The essential oil from Thymus praecox ssp. arcticus growing in Iceland. PubMed: Enzymatic formation of nerolidol in cell-free extract of Rhodotorula glutinis. PubMed: Improved preparation of (E)-β-farnesene and its activity with economically important aphids. PubMed: [Constituents of Aristolochia triangularis]. PubMed: Effects of vitamin A and ascorbic acid on in vitro cholesterol biosynthesis in the rat. PubMed: Volatile constituents of Trichothecium roseum. PubMed: All-trans-farnesol: a naturally occurring antitranspirant? PubMed: Non enzymic formation of nerolidol from farnesyl pyrophosphate in the presence of bivalent cations. PubMed: Identification and quantitative analysis of the volatile substances emitted by maturing cotton in the field. PubMed: Metabolic transformation of mevalonic Acid by an enzyme system from peas. PubMed: [Not Available].