3-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-yl)-1-(3-hydroxybenzyl)imidazolidine-2,4-dione

Export Excel

3-[1-[(3,5-dimethylisoxazol-4-yl)methyl]pyrazol-4-yl]-1-[(3-hydroxyphenyl)methyl]imidazolidine-2,4-dione

CAS: 1119831-25-2 C19 H19 N5 O4 MW: 381.39223000

Identification

Name3-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-yl)-1-(3-hydroxybenzyl)imidazolidine-2,4-dione
IUPAC3-[1-[(3,5-dimethylisoxazol-4-yl)methyl]pyrazol-4-yl]-1-[(3-hydroxyphenyl)methyl]imidazolidine-2,4-dione
CAS Number1119831-25-2
FDA UNII1P43YY1KO2
Molecular FormulaC19 H19 N5 O4
Molecular Weight381.39223000

Regulatory

JECFA Food Flavoring2161 3-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-yl)-1-(3-hydroxybenzyl)imidazolidine-2,4-dione
DG SANTE Food Flavourings16.127 3-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-yl)-1-(3-hydroxybenzyl)imidazolidine-2,4-dione
FEMA Number4725
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)1119831-25-2 ; 3-(1-((3,5-DIMETHYLISOXAZOL-4-YL)METHYL)-1H-PYRAZOL-4-YL)-1-(3- HYDROXYBENZYL)IMIDAZOLIDINE-2,4-DIONE

Physical Properties

Appearance white to cream solid (est)
Assay 99.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 135.00 to 136.00 °C. @ 760.00 mm Hg
Boiling Point 636.00 to 637.00 °C. @ 760.00 mm Hg (est)
Flash Point 642.00 °F. TCC ( 338.70 °C. ) (est)
Soluble in alcohol
Insoluble in water

Organoleptic Properties

Odor Description bland

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavor enhancers, bitter taste blockers
Recommendation for 3-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-yl)-1-(3-hydroxybenzyl)imidazolidine-2,4-dione usage levels up tonot for fragrance use.
Threshold of Concern90 (μg/person/day)
Structure ClassIII
baked goods-
beverages(nonalcoholic)2.00000
beverages(alcoholic)-
breakfast cereal20.00000
cheese-
chewing gum300.00000
condiments / relishes20.00000
confectionery froastings20.00000
egg products-
fats / oils-
fish products-
frozen dairy20.00000
fruit ices20.00000
gelatins / puddings20.00000
granulated sugar-
gravies-
hard candy75.00000
imitation dairy2.00000
instant coffee / tea2.00000
jams / jellies-
meat products-
milk products2.00000
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables20.00000
seasonings / flavors25.00000
snack foods20.00000
soft candy75.00000
soups2.00000
sugar substitutes2.00000
sweet sauces-
Dairy products, excluding products of category 02.0 (01.0)1.00000
Fats and oils, and fat emulsions (type water-in-oil) (02.0)-
Edible ices, including sherbet and sorbet (03.0)2.00000
Processed fruit (04.1)-
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2)-
Confectionery (05.0)8.00000
Chewing gum (05.3)-
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0)8.00000
Bakery wares (07.0)-
Meat and meat products, including poultry and game (08.0)-
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0)-
Eggs and egg products (10.0)-
Sweeteners, including honey (11.0)-
Salts, spices, soups, sauces, salads, protein products, etc. (12.0)25.00000
Foodstuffs intended for particular nutritional uses (13.0)1.00000
Non-alcoholic ("soft") beverages, excl. dairy products (14.1)2.00000
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2)-
Ready-to-eat savouries (15.0)8.00000
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0)-

Chemical sources Association Inc

Exchange of knowledge

Need This Item for Flavor? You can contact the Chemical Sources Association.

View All Website

Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

3-[1-[(3,5- dimethyl-4-isoxazolyl)methyl]-1H-pyrazol-4-yl]-1-[(3-hydroxyphenyl)methyl]-2,4-imidazolidinedione 3-{1-[(3,5- dimethylisoxazol-4-yl)methyl]-1H-pyrazol-4-yl}-1-(3-hydroxybenzyl)imidazolidine-2,4-dione 3-[1-[(3,5- dimethylisoxazol-4-yl)methyl]pyrazol-4-yl]-1-[(3-hydroxyphenyl)methyl]imidazolidine-2,4-dione Google Patents: Identification of human T2R receptors that respond to bitter compounds that elicit the bitter taste in compositions, and the use thereof in assays to identify compounds that inhibit (block) bitter taste in compositions and use thereof Leffingwell & Associates: Flavor Properties of FEMA GRAS List 25 flavor chemicals