2,3,5,6-tetramethyl pyrazine
2,3,5,6-tetramethylpyrazine
Identification
| Name | 2,3,5,6-tetramethyl pyrazine |
| IUPAC | 2,3,5,6-tetramethylpyrazine |
| CAS Number | 1124-11-4 |
| EINECS | 214-391-2 |
| FDA UNII | V80F4IA5XG |
| Molecular Formula | C8 H12 N2 |
| Molecular Weight | 136.19764000 |
| MDL Number | MFCD00006146 |
| Nikkaji Number | J39.647H |
| Beilstein | 0113100 |
| CoE Number | 734 |
| XlogP3 | 1.30 (est) |
Regulatory
| JECFA Food Flavoring | 780 2,3,5,6-tetramethylpyrazine |
| DG SANTE Food Flavourings | 14.018 2,3,5,6-tetramethylpyrazine |
| FEMA Number | 3237 |
| FDA | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF) | 1124-11-4 ; 2,3,5,6-TETRAMETHYLPYRAZINE |
Physical Properties
| Appearance | white crystals (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | Yes |
| Melting Point | 85.00 to 90.00 °C. @ 760.00 mm Hg |
| Boiling Point | 190.00 °C. @ 760.00 mm Hg |
| Vapor Pressure | 0.671000 mmHg @ 25.00 °C. (est) |
| Vapor Density | 4.7 ( Air = 1 ) |
| Flash Point | > 200.00 °F. TCC ( > 93.33 °C. ) |
| logP (o/w) | 1.280 |
| Soluble in | alcohol |
| Stability | alcoholic fine fragrance, good |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | perfuming agents |
Organoleptic Properties
| Odor Description |
at 10.00 % in dipropylene glycol. Nutty, musty and vanilla with dry, brown cocoa nuances smoke, herbaceous, dry Nutty Chocolate Coffee Nutty, chocolate, roasted, tea. Powerful
|
| Odor sample from | CA Aromatics Company Inc. |
| Taste Description |
nutty musty weedy earthy cocoa peanut coffee asparagus at 150.00 ppm. sweet, chocolate, coffee, cocoa, fermented
|
Safety Information
| Preferred SDS | View |
| European information | Most important hazard(s): |
| Oral/Parenteral Toxicity | gavage-rat LD50 1910 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | cosmetic, flavor and fragrance agents |
| RIFM Fragrance Material Safety Assessment | Search |
| Recommendation for 2,3,5,6-tetramethyl pyrazine usage levels up to | 0.6000 % in the fragrance concentrate. |
| Maximised Survey-derived Daily Intakes (MSDI-EU) | 6.70 (μg/capita/day) |
| Maximised Survey-derived Daily Intakes (MSDI-USA) | 19.00 (μg/capita/day) |
| Structure Class | II |
| baked goods | - |
| beverages(nonalcoholic) | - |
| beverages(alcoholic) | - |
| breakfast cereal | - |
| cheese | - |
| chewing gum | - |
| condiments / relishes | - |
| confectionery froastings | - |
| egg products | - |
| fats / oils | - |
| fish products | - |
| frozen dairy | - |
| fruit ices | - |
| gelatins / puddings | - |
| granulated sugar | - |
| gravies | - |
| hard candy | - |
| imitation dairy | - |
| instant coffee / tea | - |
| jams / jellies | - |
| meat products | - |
| milk products | - |
| nut products | - |
| other grains | - |
| poultry | - |
| processed fruits | - |
| processed vegetables | - |
| reconstituted vegetables | - |
| seasonings / flavors | - |
| snack foods | - |
| soft candy | - |
| soups | - |
| sugar substitutes | - |
| sweet sauces | - |
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