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N-[N-[3-(3-hydroxy-4-methoxyphenyl)propyl-alpha-L-phenylalanine methyl ester, monohydrate

CAS: 714229-20-6 C24 H32 N2 O8 MW: 476.52664000 sweet
All Ingredients Aromatic Ingredients CAS Numbers Flavor Ingredients Food Additives - Direct

Identification

Nameadvantame
IUPAC(3R)-4-[[(1S)-1-benzyl-2-methoxy-2-oxo-ethyl]amino]-3-[3-(3-hydroxy-4-methoxy-phenyl)propylamino]-4-oxo-butanoic acid hydrate
CAS Number714229-20-6
FDA UNII3ZA6810AWX
Molecular FormulaC24 H32 N2 O8
Molecular Weight476.52664000

Regulatory

FDA/DG SANTE Petitions, Reviews, NoticesFR DOC # 2012-26315
JECFA Food AdditiveAdvantame
GSFA CodexAdvantame (969)
DG SANTE Food Additivesadvantame
FEMA Number4716
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)714229-20-6 ; ADVANTAME
FDA RegulationFDA PART 172—FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Flash Point 32.00 °F. TCC ( 0.00 °C. ) (est)
Soluble in alcohol
Insoluble in water

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorysweeteners, flavor enhancers
Recommendation for advantame usage levels up tonot for fragrance use.
baked goods20.00000
beverages(nonalcoholic)1.35000
beverages(alcoholic)3.00000
breakfast cereal-
cheese-
chewing gum40.00000
condiments / relishes3.00000
confectionery froastings3.75000
egg products-
fats / oils3.00000
fish products-
frozen dairy0.90000
fruit ices-
gelatins / puddings3.75000
granulated sugar-
gravies-
hard candy-
imitation dairy0.75000
instant coffee / tea-
jams / jellies-
meat products-
milk products0.90000
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy3.75000
soups-
sugar substitutes-
sweet sauces-

No supplier data available

Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

aminosweet (3R)-4-[[(1S)-1- benzyl-2-methoxy-2-oxo-ethyl]amino]-3-[3-(3-hydroxy-4-methoxy-phenyl)propylamino]-4-oxo-butanoic acid hydrate N-[N-[3-(3- hydroxy-4-methoxyphenyl)propyl-alpha-L-phenylalanine methyl ester, monohydrate N-[N-[3-(3- hydroxy-4-methoxyphenyl)propyl-alpha-laevo-phenylalanine methyl ester monohydrate (N-[N-[3-(3- hydroxy-4-methoxyphenyl)propyl]-L-a-aspartyl]-L-phenylalanine 1-methyl ester) monohydrate (R)-3-[3-(3- hydroxy-4-methoxyphenyl)propylamino]-4-[(S)-1-methoxy-1-oxo-3-phenylpropan-2-ylamino]-4-oxobutanoic acid hydrate Google Patents: Sweetener compositions and uses thereof US Patents: 8,945,652 - High-potency sweetener for weight management and compositions sweetened therewith EU Patents: ASPARTYL DIPEPTIDE ESTER DERIVATIVES AND SWEETENERS Leffingwell & Associates: Flavor Properties of FEMA GRAS List 25 flavor chemicals EU Patents: NOVEL ASPARTYL DIPEPTIDE ESTER DERIVATIVES AND SWEETENERS