piperine

piperidine, 1-[5-(3,4-methylenedioxyphenyl)-1-oxo-2, 4-pentadienyl]-

CAS: 7780-20-3 C17 H19 N O3 MW: 285.34303000

All Ingredients Aromatic Ingredients CAS Numbers EINECS Numbers FEMA Numbers Flavor Ingredients Found in Nature Fragrance Ingredients JECFA Numbers Odor Substantivity

Identification

Name	piperine
IUPAC	5-(1,3-benzodioxol-5-yl)-1-piperidin-1-ylpenta-2,4-dien-1-one
CAS Number	7780-20-3
FDA UNII	Search
Molecular Formula	C17 H19 N O3
Molecular Weight	285.34303000
Beilstein	0090741
XlogP3	3.50 (est)

Regulatory

Physical Properties

Appearance	white to yellow crystalline powder (est)
Assay	96.00 to 100.00
Food Chemicals Codex Listed	No
Boiling Point	498.00 to 499.00 °C. @ 760.00 mm Hg (est)
Flash Point	492.00 °F. TCC ( 255.30 °C. ) (est)
logP (o/w)	3.365 (est)
Soluble in	alcohol
Insoluble in	water

No sensory data available

Safety Information

Oral/Parenteral Toxicity	intravenous-mouse LD50 71 mg/kg
Dermal Toxicity	Not determined
Inhalation Toxicity	Not determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements', 'U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#05220']

Safety in Use

Category	flavor and fragrance agents
RIFM Fragrance Material Safety Assessment	Search

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7780-20-3 Piperine 95%

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Potential Uses

None Found

Natural Occurrence

dill seed pepper black pepper pepper black pepper fruit pepper black pepper leaf pepper black pepper leaf oil pepper black pepper root pepper black pepper seed pepper black pepper seed oil pepper black pepper shoot pepper black pepper stem

Synonyms

1-(5-(1,3- benzodioxol-5-yl)-1-oxo-2,4-pentadienyl) piperidine 5-(1,3- benzodioxol-5-yl)-1-piperidin-1-ylpenta-2,4-dien-1-one 1-[5-(3,4- methylenedioxyphenyl)-1-oxo-2, 4-pentadienyl]piperidine 1-(5-(3,4- methylenedioxyphenyl)-1-oxo-2,4-pentadienyl)piperidine piperidine, 1-(5-(1,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl)- piperidine, 1-(5-(3,4-methylenedioxyphenyl)-1-oxo-2,4-pentadienyl)- piperidine, 1-[5- (1,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]- piperidine, 1-[5-(3,4-methylenedioxyphenyl)-1-oxo-2, 4-pentadienyl]- piperoyl piperidine 1- piperoyl piperidine 1- piperoyl-piperidine piperoylpiperidine 1- piperoylpiperidine PubMed: Piperine: researchers discover new flavor in an ancient spice. PubMed: Enhancement of responses to sequential presentation of oral chemical irritants. PubMed: Green tea polyphenol epigallocatechin-3-gallate shows therapeutic antioxidative effects in a murine model of colitis. PubMed: Effects of oral chemical irritation on taste. PubMed: [Studies on the chemical constituents of Piper macropodum C.DC]. PubMed: Spectrophotometric analysis of irradiated spices. PubMed: Carcinogenicity testing of some constituents of black pepper (Piper nigrum). PubMed: Anti-inflammatory activity of piperine.