cyclomethicone
polydimethylcyclosiloxane
Identification
| Name | cyclomethicone |
| CAS Number | 69430-24-6 |
| FDA UNII | NMQ347994Z |
| Molecular Formula | unspecified |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 1.55 mg/L @ 25 °C (est) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | antistatic agents |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | oral-rat LD50 > 16 ml/kg |
| Dermal Toxicity | skin-rabbit LD50 > 16 ml/kg |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | cosmetic agents |
| Recommendation for cyclomethicone usage levels up to | not for fragrance use. |
| Recommendation for cyclomethicone flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
cyclopolydimethyl siloxane
cyclopolydimethylsiloxane
dimethyl cyclopolysiloxane
dimethylcyclopolysiloxane
dow corning 344
dow corning X 2-1401
gel base SIL
polydimethyl siloxy cyclics
polydimethylcyclosiloxane
sentry cyclomethicone
PubMed:
Dry oil powders and oil foams stabilised by fluorinated clay platelet particles.
PubMed:
Modified silicone elastomer vaginal gels for sustained release of antiretroviral HIV microbicides.
PubMed:
Concentrations of cyclic volatile methylsiloxanes in European cosmetics and personal care products: prerequisite for human and environmental exposure assessment.
PubMed:
Tocopheryl acetate 20% spray for elimination of head louse infestation: a randomised controlled trial comparing with 1% permethrin creme rinse.
PubMed:
Pilot study to evaluate the effect of topical dimethicone on clinical signs and skin barrier function in dogs with naturally occurring atopic dermatitis.
PubMed:
Burns due to dimeticone with cyclometicone 5 excipient anti-lice lotion.
PubMed:
Effectiveness of isopropyl myristate/cyclomethicone D5 solution of removing cuticular hydrocarbons from human head lice (Pediculus humanus capitis).
PubMed:
Safety assessment of cyclomethicone, cyclotetrasiloxane, cyclopentasiloxane, cyclohexasiloxane, and cycloheptasiloxane.
PubMed:
[Head louce... an update].
PubMed:
[In vitro efficacy of three novel delousing formulations against the head louse (Pediculus capitis L.)].
PubMed:
Update on treatments for head lice.
PubMed:
Update on treatments for head lice.
PubMed:
Clinical efficacy evaluation of a novel barrier protection cream.
PubMed:
Clinical safety evaluation of a novel barrier protection cream.
PubMed:
Study of sensory properties of emollients used in cosmetics and their correlation with physicochemical properties.
PubMed:
Novel anhydrous emulsions: formulation as controlled release vehicles.
PubMed:
Effects of silicone emulsifiers on in vitro skin permeation of sunscreens from cosmetic emulsions.
PubMed:
Texture optimization of water-in-oil emulsions.
PubMed:
Stabilization of emulsions using polymeric surfactants based on inulin.
PubMed:
Compound allergy to Vea Oil.
PubMed:
O/W microemulsion as a vehicle for sunscreens.
PubMed:
Migration of antioxidant additives from various polyolefinic plastics into oleaginous vehicles.
PubMed:
Effect of occlusion on the percutaneous penetration of linoleic acid and glycerol.
PubMed:
Toxicology and humoral immunity assessment of octamethylcyclotetrasiloxane (D4) following a 28-day whole body vapor inhalation exposure in Fischer 344 rats.
PubMed:
Effective sunscreen ingredients and cutaneous irritation in patients with rosacea.
PubMed:
Rheology of siloxane-stabilized water in silicone emulsions.
PubMed:
Study of a ternary diagram gel according to a methodology of experimental research.