guaiacyl phenyl acetate

2-methoxyphenyl phenylacetate

CAS: 4112-89-4 C15 H14 O3 MW: 242.27418000 balsamic phenolic

Identification

Nameguaiacyl phenyl acetate
IUPAC(2-methoxyphenyl) 2-phenylacetate
CAS Number4112-89-4
EINECS223-898-8
FDA UNIILLO759386W
Molecular FormulaC15 H14 O3
Molecular Weight242.27418000
MDL NumberMFCD00025724
Nikkaji NumberJ224.918I
CoE Number238
XlogP33.00 (est)

Regulatory

JECFA Food Flavoring719 guaiacyl phenylacetate
DG SANTE Food Flavourings09.711 guaiacyl phenylacetate
FEMA Number2535
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)4112-89-4 ; GUAIACYL PHENYLACETATE
FDA RegulationFDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION

Physical Properties

Appearance white to yellowish brown crystalline powder (est)
Assay 97.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 39.00 to 42.00 °C. @ 760.00 mm Hg
Boiling Point 150.00 °C. @ 0.40 mm Hg, 310.00 °C. @ 760.00 mm Hg
Acid Value 1.00 max. KOH/g
Vapor Pressure 0.000033 mmHg @ 25.00 °C. (est)
Vapor Density 8.3 ( Air = 1 )
Flash Point > 212.00 °F. TCC ( > 100.00 °C. )
logP (o/w) 3.041 (est)
Shelf Life 24.00 month(s) or longer if stored properly.
Storage store in cool, dry place in tightly sealed containers, protected from heat and light.
Soluble in alcohol
Similar Items note

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesperfuming agents

Organoleptic Properties

Odor Strength medium ,
Substantivity 400 hour(s) at 100.00 %
Odor Description
at 10.00 % in dipropylene glycol.
Sweet, chemical-like, with a phenolic and floral honey nuance
meaty; smoky
Odor sample from Sigma-Aldrich
Taste Description
at 15.00 ppm.
sweet honey

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavor and fragrance agents
RIFM Fragrance Material Safety AssessmentSearch
Recommendation for guaiacyl phenyl acetate usage levels up to3.0000 % in the fragrance concentrate.
Maximised Survey-derived Daily Intakes (MSDI-EU)0.37 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA)2.00 (μg/capita/day)
baked goods-
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum-
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy-
fruit ices-
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

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Potential Uses

FR acacia FR allspice FR alpine bouquet FR amber FR animal FR autumn FR azalea FL bacon FR balsam FL barley FR bayberry FR beeswax absolute replacer FR bouquet FR cabreuva wood FR calamus oil replacer FR carnation FR cassia FR cassia blossom FR castoreum FR chestnut blossom FR christmas FL/FR cistus FR clove FR clove blossom FR clover FL cookie FL/FR copaiba balsam FR coronilla FR country meadow FR cyclamen FR deertongue absolute replacer FR dogwood FR eglantine FR fern FR fig FR flouve FR flouve blossom FR forest FR ginger white ginger FL/FR guaiacwood FR gurjun balsam FR habuba FR hawthorn FR hay new mown hay FR heather FR hinoki oil replacer FR honey FR honeysuckle FR hugonia FR incense FR iris blossom FR jonquil FR labdanum FR linden flower FR millefleurs FR moss FR musk FR opoponax FR oriental FR orris FR osmanthus FR petunia FR phlox FR pinion FL praline FR rose moss rose FR rose tea rose FL smoke FR spice FR sweet grass FR vanilla FR wisteria FL/FR yerba mate

Natural Occurrence

not found in nature

Synonyms

acetic acid, phenyl-, O-methoxyphenyl ester benzene acetic acid 2-methoxyphenyl ester benzeneacetic acid, 2-methoxyphenyl ester guaiacol phenyl acetate guaiacol phenylacetate guaiacyl phenyl acetate guaiacyl phenylacetate o- methoxyphenol phenylacetate 2- methoxyphenyl phenyl acetate 2- methoxyphenyl phenylacetate methoxyphenyl phenylacetate, o- (2- methoxyphenyl) 2-phenylacetate o- methyl catechol acetate ortho- methyl catechol acetate o- methylcatechol acetate methylcatechol acetate, o- o- methylcatechol phenylacetate phenyl acetic acid o-methoxyphenyl ester phenyl acetic acid ortho-methoxyphenyl ester phenylacetic acid o-methoxyphenyl ester PubMed: Nicotine alters limbic function in adolescent rat by a 5-HT1A receptor mechanism. PubMed: The role of melanin-concentrating hormone-1 receptors in the voiding reflex in rats. PubMed: In vivo effects of the putative cognitive enhancer KA-672.HCl in comparison with 8-hydroxy-2-(di-N-propylamino) tetralin and haloperidol on dopamine, 3,4-dihydroxyphenylacetic acid, serotonin and 5-hydroxyindoleacetic acid levels in striatal and cortical brain regions. PubMed: Clinical and gastroscopic evaluation of amtolmetin guacyl versus diclofenac in patients with rheumatoid arthritis. PubMed: Functional alpha2C-adrenoceptors in human neuroblastoma SH-SY5Y cells. PubMed: 5-HT1A receptor agonist effects of BMY-14802 on serotonin release in dorsal raphe and hippocampus. PubMed: Role of 5-HT1A receptors in the ability of mixed 5-HT1A receptor agonist/dopamine D2 receptor antagonists to inhibit methylphenidate-induced behaviors in rats. PubMed: Ipsapirone enhances the dopamine outflow via 5-HT1A receptors in the rat prefrontal cortex. PubMed: Behavioral studies with anxiolytic drugs. VI. Effects on punished responding of drugs interacting with serotonin receptor subtypes. PubMed: BRL 20596, a novel anilide with central dopamine antagonist activity. PubMed: THE PROPERTIES OF SYRINGYL, GUAIACYL AND P-HYDROXYPHENYL ARTIFICIAL LIGNINS.